Super spotty. As a workaround, I’ve used ensembl.org?redirect=no and that seems to work, otherwise maybe try the beta version?
20.02.2026 01:03
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Super spotty. As a workaround, I’ve used ensembl.org?redirect=no and that seems to work, otherwise maybe try the beta version?
Switching fields or wanting to become an expert in #zebrafish research?
The @mblscience.bsky.social 2026 Zebrafish Development & Genetics course offers a fantastic opportunity to learn from leaders in the field!
Application deadline: March 2
Please spread the word!
www.mbl.edu/education/ad...
GetHIRED! REGISTRATION IS NOW OPEN - Application due Thursday, March 5 Ideal for Postdoctoral Researchers Academic Job Market Insight -Take stock of what you want -Know your options -Prepare outstanding job packet materials -Organize your research & chalk talks -Perfect your interview & avoid the pitfalls Course Features -Six asynchronous online modules -Virtual meetings with an experienced facilitator -Peer feedback, support, & expert advice Course Dates: April 14 – June 23, 2026 Course Fee: SDB Members: $499; Non-Members: $599 Deadline: March 5, 2025 Society for Developmental Biology logo QR Code for GetHIRED! website
#Postdocs! Going on academic job market? Apply for SDB GetHIRED! Take stock of what you want, know your options, prepare an outstanding job packet, organize your research & chalk talks, perfect your interview. Deadline: March 5 sdbonline.org/gethired
Moreover, ICE must be destroyed
Happy to share our paper now out in @cp-cellreports.bsky.social - and check out our thread about the findings at bsky.app/profile/vale...
Candid photo of Zara Weinberg. She has short red hair, bangs and glasses. She is laughing.
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
Thanks so much, Kevin! Antonio Giraldez and I are co-corresponding authors on this paper. But yes, this is my first shared senior-author primary research paper after starting my lab ❤️
Thanks to thoughtful & incisive reviewers, this #peer-reviewed study is a vastly improved version of our #preprint. Congrats to co-first authors Scott Youlten & Liyun Miao in this work led w/Antonio Giraldez/lab members and me. We look forward to exploring new questions this study now enables! (6/6)
Loss of the transient totipotent embryonic state still directed embryonic cells into distinct states in vivo, suggesting resiliency of some gene expression states. We’re excited to further dissect the cellular decisions possible when the first embryonic reprogramming step is bypassed. (5/6)
We found that NPS are required for proper cell identity for most – but not all – lineages, likely through nuclear & cytoplasmic reprogramming. Intriguingly, some mutant cells highly resembled primordial germ cells, while other mutant cells acquired defined motorneuron-like states. (4/6)
When these mutant cells were transplanted into a wild type environment, we found that while most cells died, some cells still developed! By isolating & performing #singlecell RNA profiling, we found that multiple gene expression programs shaped distinct new cell states. (3/6)
Embryos rely on Nanog, Pou5f3 (Oct4), & Sox19b (Sox2) (NPS) deposited in the egg for reprogramming in the maternal-to-zygotic transition, allowing embryonic cells to start differentiating & acquire new cell states. When these factors are missing, embryos fail to gastrulate. But… (2/6)
Graphical abstract describing the main findings. Top, Nanog, Pou5f3, and Sox19b (NPS) work together for cellular reprogramming following fertilization of the egg and sperm in the embryo's maternal-to-zygotic transition. Clearance of the maternal program, plus activation of the zygotic and late zygotic genes expression programs later in development, together will enable gene expression programs towards cellular differentiation. In maternal-zygotic NPS (mzNPS) mutant embryos, there is a failure of reprogramming and subsequently no gastrulation. However, when mzNPS embryonic cells are transplanted into wild type embryos, some cells survive and form mixed cell states, likely due to failed nuclear and cytoplasmic reprogramming. We find that some gene expression states, including primordial germ cell-like and motoneuron-like cell states, are able to develop in vivo, bypassing the loss of NPS-mediated embryonic reprogramming.
What cell states are possible when they are missing key factors - Nanog, Pou5f3 (Oct4), & Sox19b (Sox2) - that are required for the first embryonic reprogramming steps? Follow along with our latest publication, finally out at doi.org/10.1016/j.ce... #devbio #reprogramming #zebrafish #embryo (1/6)
The President’s Postdoctoral Fellowship Program, PPFP, has been a jewel in the crown for faculty development and recruitment at the University of California for years and the results have been an expanded faculty with almost 100% tenure rates — unprecedented success.
Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
Please help distribute this announcement for the Ph.D. in Biology Program @stowersinstitute.bsky.social
I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events.
Deafening Quiet from the Scientific Establishment
jeremymberg.github.io/jeremyberg.g...
1/14
As of this week, every public university in California is under investigation from the Trump administration for alleged antisemitism www.latimes.com/california/s...
“I will end my career writing dissent, that is my future. And you understand that you’re writing for a future society. That dissents are not about today. Dissents are writing for a future society that will take that dissent, that will be ready for that dissent, & enact it”
@nhannahjones.bsky.social
I wrote this for my US friends and colleagues, but also for all of us. Lessons from the past. open.substack.com/pub/verakemp...
Trump wants UCLA to pay $1.2 billion to settle allegations it violated civil rights law. I took a look at the more than 7,300-word proposed UCLA settlement. Here's the detailed breakdown of Trump's plan to remake one of the nation's top public campuses: www.latimes.com/california/s...
Congrats!!
Last week, Boston received a letter from AG Bondi threatening to prosecute officials and withhold funds unless we cooperate with carrying out mass deportations.
The US Attorney General asked for a response by today, so here it is: stop attacking our cities to hide your administration’s failures.
I've now been allowed and asked to share more details about what's going down at the University of Oregon, which involves imminent announcement of firings, among others, of tenure-track and tenured faculty. Given the units impacted (see below), please share this with your professional networks in related disciplines and start getting ready to put pressure (or begin putting pressure already) on the University of Oregon upper admin to abandon this alleged plan before they finalize it. It appears that, with no prior consultations, the departments of Religion and Classics (two separate units), and the programs in Russian, East European, and Eurasian Studies, German & Scandinavian, Judaic Studies, Arabic Studies, and Holocaust Studies (the latter five all parts of a previously-consolidated mega unit called the Schnitzer School of Global Studies and Languages) are facing imminent announcement of elimination (expected the week of Sept 7), with layoffs of pre-tenure, tenured, and career faculty in these units. The reason given is "financial exigency" -- upper administrations of several universities across the country (and in blue states like Oregon also) appear to be giddy to use the context of Trump attacks on higher ed to dismantle the humanities. Faculty at OU won a faculty union not long ago; this may be, in part, a retaliation for that, I've been told. The union is working with AAUP, etc.; my understanding is that the maximum spotlight is needed at this point.
A massive attack on several humanities units (Arabic Studies, Judaic Studies, Holocaust Studies, Classics, Religion, German & Scandinavian, Russian/East European/Eurasian Studies) *and* tenure now unfolding at the University of Oregon (a blue state!). Closure of units and faculty layoffs threatened.
Congratulations!!!
*Please read and share!* My NIH funds at UCLA were suspended last week.
It's hard to find the words to describe the impact of these grant suspensions. I have felt speechless and heartbroken that people in my lab, my friends, colleagues, researchers, trainees, and undergrads 1/9
BBC International Editor Jeremy Bowen has confirmed that the entire Al Jazeera team in Gaza City has been killed.
There is no nice, gentle way to say, “okay so a nation is, in effect, a currency, a military, and resource allocation. If you break all of those, you do not…have a country.”
The billion dollars is the least of it. It’s universities’ autonomy, independence, and integrity that Trump is really after. www.cnn.com/2025/08/08/p...