Axel Laurell

Very grateful to receive support from the @acceleratescience.bsky.social programme to investigate the association between sex hormones and dementia risk.

For anyone with experience in neuroimaging, we have a unique opportunity to join the old-age psychiatry group in Cambridge. You'll be working with a great team across the UK and Ireland on the PREVENT-Dementia cohort study.

www.cam.ac.uk/jobs/researc...

Hear Dr Axel Laurell @axellaurell.bsky.social share the latest news from the PREVENT General Assembly.
With so much potential in the programme- we can't wait to see what happens next!

🌟 New paper! 🌟

Hypothalamic imaging in Alzheimer's disease and Lewy-body dementia: A systematic review and meta-analysis.

Hypothalamic volume is reduced by 10% in Alzheimer's disease, but the impact on symptoms is uncertain.

www.sciencedirect.com/science/arti...

Today a quick stop in Wales for the #RCPsychIC

@rcpsych.bsky.social

It was really great to be at #EuroPAD this week to present my research on the hypothalamus in dementia. Also managed to spend some time exploring the beautiful Barcelona. Now back to much colder ground for Swedish midsummer. @barcelonabeta.bsky.social

Hypothalamic volume, sleep, and APOE genotype in cognitively healthy adults INTRODUCTION Sleep dysfunction in those at higher risk of dementia may be associated with early structural changes to the hypothalamus. METHODS We used multivariate regression to analyze self-repo.....

🚨 New paper! 🚨

Increasing age and APOE4 is associated with hypothalamic changes and worse sleep in two large cohorts studies.

I've learnt so much working with this project and it's amazing to see it in published form!

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Great to be at the @rcpsych.bsky.social old age conference showcasing some really important projects on fracture risk, communication strategies and future planning of services!

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Great to be at the international Lewy body dementia conference in Amsterdam presenting my recent systematic reviews.

Papers:
www.sciencedirect.com/science/arti...

www.sciencedirect.com/science/arti...

Long-Term Dementia Risk in Parkinson Disease | Neurology Background and ObjectivesIt is widely cited that dementia occurs in up to 80% of patients with Parkinson disease (PD), but studies reporting such high rates were published over two decades ago, had re...

doi.org/10.1212/WNL....

🚨 New paper! 🚨

A systematic review of diffusion tensor imaging in Lewy-body Dementia.

I'm really proud that this complex paper is now available.

The figure shows the brain regions with changes in AD (red) and DLB (green), as shown by DTI.

www.sciencedirect.com/science/arti...

Breakthrough drugs herald ‘new era’ in battle against dementia, experts predict Medical advances make pills to treat Alzheimer’s disease viable, though challenges remain in sharing gains globally

www.theguardian.com/global-devel...

Yup.