I want to write a fun little post on what we've learned in neuroscience in the last 20 years. What are the most interesting results you can think of? Biggest trends?
08.03.2026 01:17
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I want to write a fun little post on what we've learned in neuroscience in the last 20 years. What are the most interesting results you can think of? Biggest trends?
DNN models of the brain are getting bigger. Are we replacing one complicated system in vivo with another in silico?
In new work, we seek the *smallest* DNN models of visual cortex, balancing prediction with parsimony.
It turns out these compact models are surprisingly small!
rdcu.be/e5H8G
Some soup for you!
CAMs or soup?
Lots of things to think about in these posts from @patrickmineault.bsky.social -- nice to see more blog entries :)
Here's the second one: www.neuroai.science/p/cell-types... . I made a New Year's resolution to blog more, and so far I'm sticking to it!
What are cell types good for, computationally? Encoding innate behavior! In this 2-parter, I break down the relationship between cell types—which I had, in years prior, dismissed as mere implementation detail—and computation. I changed my mind!
www.neuroai.science/p/cell-types...
Book cover. A silhouette of a person's head filled with colorful geometric shapes—perhaps symbolizing cognitive resources or deployment thereof. The style is attractive and modern, if generic. text: The Rational Use of Cognitive Resources Falk Lieder, Frederick Callaway, Thomas L. Griffithts
I'm excited to announce that I had my first (co-authored) book published today! "The Rational Use of Cognitive Resources" with Falk Lieder and Tom Griffiths (@cocoscilab.bsky.social ). You can read it for free! (see thread)
The revised version of our paper on the impact of top-down feedback is now out @elife.bsky.social:
doi.org/10.7554/eLif...
tl;dr: we show that using human-brain-like feedback/anatomy in a deep RNN leads to human-like visual biases!
This work was led by @tmshbr.bsky.social
#NeuroAI 🧠📈 🧪
🚨 new work from the lab on how eye movements 👀 versus orofacial movements influence 🐭 visual cortex activity 🧠 #neuroscience #behavior #neuroAI
Discovered @patrickmineault.bsky.social's excellent Good Research Code Handbook today, which was always awesome, but is even more necessary as more scientists consider integrating coding agents into their workflows.
goodresearch.dev
www.neuroai.science/p/claude-cod...
Why yes this is very helpful for me as an undergrad. I like the way the methods that Patrick laid, how to aid research using AI and its pros vs cons
From @patrickmineault.bsky.social, on how scientists can use Claude Code to help with all the heavy data analysis coding that is a big part of our lives.
use a make system, set up folder structures, write tests, use git, use package managers. Notes on notebooks and visualizations too. 🧪
🚨📜+🧵🚨 Very excited about this work showing that people with no hand function following a spinal cord injury can control the activity of motor units from those muscles to perform 1D, 2D and 3D tasks, play video games, or navigate a virtual wheelchair
By a wonderful team co-mentored w Dario Farina
Just published my review of neuroscience in 2025, on The Spike.
The 10th of these, would you believe?
This year we have foundation models, breakthroughs in using light to understand the brain, a gene therapy, and more
Enjoy!
medium.com/the-spike/20...
✈️ Montreal AI and Neuroscience is over, off to Costa Rica. Great catching up all things NeuroAI with hometown friends. Thanks for the shirt and the bagels, folks!
🔴 Live: Panel discussion #1: @ MAIN2025
The future of Neuroscience - The role of AI ?
with Andreas Tolias, Siva Reddy, Joao Sacramento, Ching Fang + Eva Portelance
Moderated by Patrick Mineault @patrickmineault.bsky.social
@andreastolias.bsky.social
What I would have done for a dataset like this to exist in grad school! One day, we'll figure out the dorsal stream. openreview.net/forum?id=Ila...
Headed to NeurIPS, looking forward to catching up with you about NeuroAI, foundation models of the brain, AI safety and AI for science
This equivocation of oscillations and continual learning is a bit of stretch... I'm surprised they didn't get dinged by the reviewers for neuro-babble. openreview.net/forum?id=nbM...
We're almost at the end of the year, and that means an end-of-year review! Send me your favorite NeuroAI papers of the year (preprints or published, late last year is fine too).
New #NeuroAI #compneurosky preprint! To better understand how target-directed learning works in the brain, we sought to engineer an artificial neural network capable of solving complex image classification tasks that comprises only experimentally-supported biological building blocks. (1/15)
iPad + Apple Pencil + Concepts
I had way too much fun making these diagrams. Sure, it's not as legible as if I had typed out the text; but I feel like these have a bit more personality
🚨 New preprint alert!
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We propose a theory of how learning curriculum affects generalization through neural population dimensionality. Learning curriculum is a determining factor of neural dimensionality - where you start from determines where you end up.
🧠📈
A 🧵:
tinyurl.com/yr8tawj3
Congrats!
Thrilled to share that our work is now published in Science! ✨
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
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Having fun facilitating this amazing group of young Profs at the #Neuro4Pros workshop with @kordinglab.bsky.social and @meganakpeters.bsky.social, @yaelniv.bsky.social, and Hannah Bayer.
Watch out world: this is the next generation of leaders!
compneurosci.com/Neuro4Pros/i...
So many arguments boil down to "my semantic boundaries are slightly different than yours"
