⚡ Greener alcohol oxidations!
Graphical review by @conchem.bsky.social & Prof. @klchemistry.bsky.social on non-transition-metal electrochemical #oxidation of alcohols. Featuring TEMPO and other mediator systems in #electrosynthesis.
🔗 Read more: bit.ly/4rRzoSr
#OrganicChemistry #ChemSky
💡 Visible light unlocking #heterocycles!
Eosin Y–catalyzed reductive cyclization of N/O-aryl bisenones affords functionalized pyrrolidines & THFs, exclusive trans #isomers & enantioenriched products!
🔗 Read the full paper: bit.ly/4tXrvwj
#ChemSky #Photochemistry #OrganicChemistry
🚨 Last call to the Thieme #Cheminar!
“Strain-Release Chemistry” with speakers Dr. Durga Hari (🇮🇳), Prof. Jérôme Waser (🇨🇭) @lcsolab.bsky.social & Prof. Peter Wipf (🇺🇸). Chaired by Akkattu T. Biju (Assoc. Editor of @synthesis1969.bsky.social)
📅 Feb 24, 2026 | ⏰ 11:00 AM(CET)
🔗 Register: bit.ly/4kGHtqm
📢 Join our next Thieme #Cheminar!
🧪 Strain-Release Chemistry
📅 Feb 24, 2026 | ⏰ 11:00 AM (CET)
Discover how strained #molecules open new pathways for innovative transformations.
Chaired by Akkattu T. Biju (Associate Editor of @synthesis1969.bsky.social)
🔗 Register here: bit.ly/4kGHtqm
🧪 New quinazoline-based #lidocaine analogue
Scalable 7-step synthesis (10-g scale) delivers a promising next-generation local anesthetic with enhanced activity and improved pharmacokinetic profile!
🔗 Read the full paper: bit.ly/4rXt4Zw
#ChemSky #MedicinalChemistry #DrugDiscovery
An efficient and mild dibromination of aromatics using Fe(NO₃)₃·9H₂O/FeBr₃ at room temperature. This protocol delivers good to excellent yields, avoids hazardous Br₂, and is scalable to gram scale. 🧪
🔗 Read here: bit.ly/4riD0gk
#ChemSky #OrganicSynthesis #Halogenation #GreenChemistry
🌱 Polar organometallic reagents can thrive in #sustainable solvents!
This graphical review highlights how organolithium, #Grignard, and related #reagents operate in water and deep eutectic solvents, redefining classical reactivity through #GreenChemistry.
🔗 Read now: bit.ly/4qVloXj
#ChemSky
🧩 Sterically controlled, template-assisted macrocyclization enables hemisquaraine #rotaxanes with enhanced #fluorescence and stability.
By combining #SupramolecularChemistry, photophysics, and DFT, this study reveals how steric effects control rotaxane formation.
🔗 Read here: bit.ly/3ZE8UaF
Asymmetric synthesis of 2-arylethylamines, key motifs in bioactive compounds and #MedicinalChemistry.
This graphical review highlights 2025 advances in metal-free and metal-catalyzed methods, including #Organocatalysis, #Photocatalysis and #Biocatalysis. 🧪
🔗 Read here: bit.ly/3LORTHq
#ChemSky
Thank you for publishing with us!
⚡ Turning alcohols into aldehydes with electricity. New open-access graphical review on electrochemical oxidations in @synopenjournal.bsky.social by @Conchem.bsky.social because chemists love schemes more than words 🤣
www.thieme-connect.com/products/ejo...
#Electrosynthesis #Aldehydes #ChemSky
Discover how [2.2]paracyclophanes (PCPs) are functionalized using transition #metals and applied as planar #chiral ligands and catalysts. This graphical review offers a overview of C–H activation strategies and their impact on #stereoselective synthesis. 🔬📘
🔗 Read here: bit.ly/4qwWRb7
#ChemSky
An iodine-doped TiO₂ #photocatalyst shows efficient degradation of toxic dyes under UV and visible light, with enhanced activity and good reusability. A promising approach for sustainable #WaterTreatment. 🌱💧
🔗 Read the full article: bit.ly/4r2zgit
#OpenAccess #ChemSky #SustainableChemistry
We’re live!
Introducing Therapeutics NOW – Thieme’s new Gold Open Access journal driving breakthroughs in translational therapeutic research.
✅ Interdisciplinary by design
✅ Broad scope & impactful article formats
✅ Ultra-fast peer review via Select Crowd Review
🔗 www.thieme.com/en-us/thieme...
⚡🔬 Can #ElectricFields direct #ChemicalReactivity?
This graphical review by Prof. Thomas Wirth & team (🇬🇧) shows how oriented external electric fields can control reaction pathways, enhance selectivity, and reduce energy input in #OrganicSynthesis.
A must-read!
🔗 bit.ly/453gvCT
#ChemSky #OpenAccess
✨ 2025 highlights ✨
🥇 #1 Most Downloaded Paper of 2025
“Sodium Nitrite (NaNO₂): An Impressive and Efficient Nitrating/Nitrosating #Reagent in #OrganicSynthesis”
Graphical review by Lamark, Barbosa & Jordão
🔗 Read now: bit.ly/4b9Di3x
#ChemSky #Chemistry #OpenAccess
✨ 2025 highlights ✨
📊 Top 5 most downloaded papers of 2025
✅ #2
A convenient #synthesis of CHF₂O-containing #pyrrolidines and related compounds — Perspective building blocks for #DrugDiscovery
by K. Levchenko et al.
🔗 Read here: bit.ly/498FiGQ
#ChemSky #OrganicChemistry
✨ 2025 highlights ✨
📊 Top 5 most downloaded papers of 2025
✅ #3
“Synthesis, In Vitro and In Silico Molecular #Docking Studies of Novel Phthalimide–Pyrimidine Hybrid Analogues to #Thalidomide as Potent #Antitubercular Agents”
by S. Youssif & team
🔗 Read now: bit.ly/49cOqKG
#ChemSky
✨ 2025 highlights ✨
📊 We’re closing the year with the Top 5 most downloaded papers of 2025.
✅ #4
“Recent #Catalytic Applications of #Porphyrin and Phthalocyanine-Based Nanocomposites in #Organic Transformations”
by P. Kumari & co-workers
🔗 Read now: bit.ly/48URmwu
#ChemSky
✨️ 2025 highlights ✨️
📊 Our final posts of the year highlight the Top 5 most downloaded papers of 2025.
✅ #5
“Development of a Novel Horner–Wadsworth–Emmons Reagent for the Facile Preparation of Mixed Phosphonoacetates"
by Shigeki Sano & team.
🔗 Read it here: bit.ly/3YcSdT2
#ChemSky #Chemistry
✨ 2025 highlights ✨
A year of global connections and great #science for the Syn journals community: 10 events across 8 countries! 🇨🇭 🇰🇷 🇪🇸 🇬🇧 🇨🇳 🇯🇵 🇵🇹 🇮🇹
Thank you to everyone who made these meetings unforgettable! Special thanks to @rohitbhatia10.bsky.social 🇮🇳 for representing us at so many conferences!
🎄 2025 highlights! 🎄
The SynOpen Best Paper Award 2024 to Ben Stokes & co-workers (Santa Clara University, 🇺🇸) for their publication "Pd-Catalyzed Transfer Hydrogenation of Alkenes Using Tetrahydroxydiboron as the Sole Hydrogen Donor"
👀 Revisit the paper: bit.ly/3MSJsuR
#Throwback #ChemSky
🎄 As 2025 comes to a close, we at @thieme-gruppe.bsky.social look back at our #Cheminar series!
From Chemical Synthesis & #Catalysts to Medicinal #Chemistry, plus special sessions and Best Paper Awardees.
Thanks to all chairs, speakers, and attendees.
👀 More Cheminars in 2026. Stay tuned!
📢 Last call for our Thieme #Cheminar!
Dive into the world of Small #Molecules in Medicinal Chemistry.
Session with Profs. Arlene G. Corrêa (🇧🇷) & Kelvin Billingsley (🇺🇸), chaired by Debabrata Maiti (🇮🇳).
📅 Dec 10, 2025 ⏰ 5 PM (CET)
🔗 Register now: bit.ly/4aDJWie
#ChemSky
📢 Cheminar Alert!
Our next Thieme #Cheminar is coming up: “Small Molecules in #MedicinalChemistry”
📅 Dec 10, 5:00 PM (CET)
Featuring Prof. Arlene Corrêa and Prof. Kelvin Billingsley, with Prof. Debabrata Maiti (EiC of @synlettjournal.bsky.social) chairing.
🔗 Register now: bit.ly/4aDJWie
#ChemSky
🧬 New #anticancer candidates from functionalized oxazoles!
M. V. Kachaeva & team report 5-S-substituted 1,3-oxazolylphosphonates and 1,3-oxazole-4-carbonitriles, with several compounds showing high potency against multiple #cancer cell lines!
📄 Read here: bit.ly/4pmeAl4
#ChemSky #MedChem #Synthesis
🔬 Prof. Ying Xia and colleagues highlight recent advances in the #synthesis of axially #chiral cycloalkanes, covering key strategies such as asymmetric allylic substitution, #alkene insertion, #carbene cross-coupling, [2+2] #cycloadditions, and #deracemization.
🔗 Read now: bit.ly/4pCRhTy
#ChemSky
Potential new type of #herbicides! 🌱
In this paper, J. Frackenpohl & team report the design, #synthesis, and #biological evaluation of substituted azetidinyl carboxamides, developed through scaffold hopping and #bioisosteric strategies.
🔗 Read the full article: bit.ly/4iplJyn
#ChemSky #SAR
Prof. Michael P. Doyle & L. De Angelis (UTSA) highlight how 1,2,3-triazine 1-oxides provide a powerful platform for constructing diverse #heterocycles. From nucleophilic substitution & #deoxygenation to Diels–Alder #reactions and more!
🔗 Read the graphical review: bit.ly/48qm7Jg
#ChemSky #Synthesis
✨ New Graphical Review!
A. V. Dobrydnev presents overview of synthetic strategies for building endocyclic sulfoximines. They possess unique #physicochemical and structural features, including #chirality and thermal stability.
🔗 Read more: bit.ly/482WRr7
#ChemSky #OrganicChemistry #Heterocycles
