Dani León-Periñán 🇵🇸's Avatar

Dani León-Periñán 🇵🇸

@danilexn

Cells talk; I build tools to listen to them Computational biologist • Occasional composer and pianist • he/him Opinions are my own.

540
Followers
658
Following
94
Posts
24.11.2024
Joined
Posts Following

Latest posts by Dani León-Periñán 🇵🇸 @danilexn

Preview
Última hora del ataque de EE UU e Israel contra Irán, en directo | Trump anuncia que cortará todo el comercio con España por ser un aliado “terrible” Sánchez hará declaraciones al respecto mañana en La Moncloa | Bruselas dice que defenderá la “plena” protección de los intereses de la UE | Aterriza en Barajas el vuelo con los más de 175 españoles r...

Spain doesn’t need to make business with a country led by a pedophile.

We’ve been around more than 3000 years, and we will be around for another 3000. We will be super happy when the US empire falls, soon.

elpais.com/internaciona...

03.03.2026 21:29 👍 0 🔁 0 💬 0 📌 0

this is embarrassing

02.03.2026 13:43 👍 0 🔁 0 💬 0 📌 0

This is such an exciting project, join us!

27.02.2026 14:48 👍 0 🔁 0 💬 0 📌 0

🚀 We're looking for people to join Malva! 🧬 @danilexn.bsky.social

Malva is the first search engine for single-cell genomics: we process massive amounts of sequencing data to enable ultrafast analysis of millions of cells.

(1/4)

27.02.2026 09:17 👍 4 🔁 4 💬 1 📌 1
Post image

SpatialZ generates virtual single-cell transcriptomics slices between experimentally measured sections, enabling accurate and efficient building of 3D cell atlases of different tissues.

www.nature.com/articles/s41...

14.01.2026 16:26 👍 10 🔁 5 💬 0 📌 1
Preview
‘A bombshell’: doubt cast on discovery of microplastics throughout human body Exclusive: Some scientists say many detections are most likely error, with one high-profile study called a ‘joke’

‘A bombshell’: doubt cast on discoveries of #microplastics throughout human body, from brain to blood, arteries to testes

Exclusive: Some scientists say many detections are most likely error, with one high-profile study called a ‘joke’

Story by me
www.theguardian.com/environment/...

13.01.2026 14:32 👍 211 🔁 70 💬 14 📌 71

MAGA: The USA economy is 40% larger than all of Europe.
Close your borders.
EU: Buddy, inflated economy does not count. GDP does not count when people cant even pay their healthcare.

07.01.2026 15:38 👍 138 🔁 17 💬 7 📌 0

nope, US rn is worse than Nazi Germany.

you have a fascist government AND nuclear weapons.

03.01.2026 21:43 👍 0 🔁 0 💬 0 📌 0

Members of Congress: stop posting online and APPEAR, PHYSICALLY on the steps of the Capitol to decry this unconstitutional violation of domestic & international law. SHOW THE PEOPLE the level of danger we are facing as a country.
@housedemocrats.bsky.social
@senatedemocrats.bsky.social

03.01.2026 17:17 👍 25802 🔁 7900 💬 719 📌 923

🤔

03.01.2026 14:20 👍 17 🔁 3 💬 0 📌 0

not safe for non-america countries to have a president these days. trump would've done this to greenland already if anybody in the administration could figure out who the main guys are in a parliamentary government

03.01.2026 13:04 👍 263 🔁 29 💬 1 📌 0

Greenland’s next.

03.01.2026 14:12 👍 176 🔁 45 💬 0 📌 0

Venezuela hoy da la imagen del mundo que traen las fuerzas reaccionarias: agresiones militares ilegales, la razón de la fuerza bruta, el capricho imperial como norma.

Un mundo de siervos en el que nadie esté a salvo.

03.01.2026 10:59 👍 876 🔁 355 💬 22 📌 14

Who would’ve thought that the pedophile that encouraged an assault to the Capitol could kidnap the president of another sovereign nation?

Wow mind blowing stuff.

03.01.2026 13:55 👍 1 🔁 0 💬 0 📌 0

And Israel

03.01.2026 13:52 👍 0 🔁 0 💬 0 📌 0

The problem is thinking that US is the world’s number one superpower.

The world’s number one superpowers are Europe and China. They’ve been for thousands of years and they’ll still be for another thousand.

US is just a third-world country with Gucci outfits.

03.01.2026 13:48 👍 1 🔁 0 💬 0 📌 0

Lourd est le parpaing des Trump, Poutine, Netanyahou et consorts sur la tartelette aux fraises du droit international.

03.01.2026 08:37 👍 417 🔁 96 💬 8 📌 5

Repeat after me: GENE 👏 EXPRESSION 👏 PROFILING 👏 DOES 👏 NOT 👏 A 👏 VIRTUAL 👏 CELL 👏 MAKE 👏

26.12.2025 12:11 👍 79 🔁 16 💬 4 📌 0

Today is a big day.

After many years of work, I’m excited to finally share a paper describing a novel approach to identifying potential breakthroughs in biomedical research, up to twelve years before the breakthrough itself occurs. 1/15

18.12.2025 20:38 👍 11 🔁 8 💬 1 📌 3
Post image

🧮 Just out in Bioinformatics Advances: “FroM Superstring to Indexing: A space-efficient index for unconstrained k-mer sets using the Masked Burrows-Wheeler Transform (MBWT)” 

Full article available: https://doi.org/10.1093/bioadv/vbaf290 

Authors include: @pavelvesely.bsky.social, @brinda.eu

05.12.2025 10:01 👍 11 🔁 3 💬 1 📌 1
El sorteo del Mundial de Fútbol 2026, en directo | Uruguay, Arabia Saudí y Cabo Verde se enfrentarán a España en la fase de grupos del Mundial La selección de Luis de la Fuente cae en el grupo H, que disputará sus partidos en Miami, Atlanta, Houston y Guadalajara | El partido inaugural será entre México y Sudáfrica el próximo 11 de junio | L...

History will remember Claudia Sheinbaum as the idiot who demanded a government to say sorry for stuff that happened 500 years ago, while taking selfies with a nazi-pedophile.

elpais.com/deportes/mun...

05.12.2025 20:10 👍 0 🔁 0 💬 0 📌 0
Preview
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology Stem cell differentiation is controlled by manipulating RNA condensates.

Selective RNA sequestration in biomolecular condensates directs cell fate transitions - @distefanolab.bsky.social @brumbaugh-lab.bsky.social go.nature.com/3X215du

28.10.2025 18:50 👍 45 🔁 14 💬 2 📌 1
Preview
Senat will 12,5 Millionen Euro investieren: NFL kommt 2025 für ein Spiel nach Berlin Die nordamerikanische Football-Liga NFL wird 2025 ein Spiel in Berlin austragen. Bis 2029 könnten zwei weitere Folgen. Die Kosten dafür sind hoch. Das Land muss trotz Haushaltskrise Millionen investie...

Berlin’s senate invests >12 mio EUR for 3 NFL games in Berlin, at a time where they cut millions at the universities that are already underfunded, with collapsing buildings. They definitely seems to have priorities that are not mine.
www.tagesspiegel.de/berlin/senat...

06.11.2025 19:49 👍 15 🔁 5 💬 2 📌 0

Needless to say that the bioinformatics analyses presented in the manuscript show all the common pitfalls/cliches.

Worst of all: no judgement of methods. Just plain belief that outputs of code interpreters are ground truth, and any contradictions are “conceptual” rather than “methodological”.

06.11.2025 14:07 👍 3 🔁 0 💬 0 📌 0

… and developing those tools and standards requires time, effort, spent by bright people and not by sloppy AI agents.

You cannot claim to have an “AI Scientist for Autonomous Discovery”, when your scRNA analysis relies on tools that are created and maintained by humans.

That’s not autonomous.

06.11.2025 13:25 👍 2 🔁 0 💬 1 📌 0

I see the value of agent-based AI. We work on developing stuff in that direction.

But claims like “Here we present Kosmos, an AI scientist that automates data-driven discovery” are just FALSE and malicious.

Discovery in bioinformatics requires an ecosystem of tools and good practices…

06.11.2025 13:25 👍 1 🔁 0 💬 1 📌 0

From the manuscript: “collectively executing an average of 42,000 lines of code and reading 1,500 papers per run”

Looking at those 42,000 lines of code, most are bioinformatics 101, stolen from tutorials/books. Many are just repeated across notebooks.

06.11.2025 13:17 👍 2 🔁 0 💬 1 📌 0

Also, the whole concept of “data-driven discovery” is super funny.

In order to get good data, there has to be very good, careful experimental design. And experimental work. And most time, lots of new methods development.

06.11.2025 13:15 👍 1 🔁 0 💬 1 📌 0

This is pure bullshit. You don’t need to run 200 LLM agents for >8 hours to do DE, GSEA and generate a couple of heatmaps.

And if you do, just spend 2 weeks learning bioinformatics and you won’t need to give money to a company selling snake oil.

arxiv.org/pdf/2511.02824

06.11.2025 13:09 👍 5 🔁 1 💬 2 📌 0
Post image

🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!

30.10.2025 17:50 👍 27 🔁 38 💬 0 📌 0