Drew Hryckowian

Scientist I – C. difficile and Gut Microbiome - Madison, Wisconsin, United States Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:Academic StaffEmployment Type...

Join us in beautiful Madison WI! In addition to the postdoc call I previously announced, I am seeking applicants for a Scientist position. IMO this position is best suited for someone who successfully completed their postdoctoral training, see here for more details: jobs.wisc.edu/jobs/scienti...

Join us this week for the MDTP student seminar, featuring Joie Ling from Hryckowian Lab!

#MDTP #UWMadison

Postdoc, Postgrad, and Research Intern Vacancies Browse Postoc and Research Intern vacancies at UW–Madison.

Postdoc position available in my lab! Project will focus on how the microbiome-derived metabolite butyrate shapes C. difficile fitness and pathogenesis & will build on our previous/ongoing work in this space. Apply here:
hr.wisc.edu/postdoc-and-...

A murine model of adult gastrointestinal colonization by Group B Streptococcus | Infection and Immunity Group B Streptococcus (Streptococcus agalactiae, GBS) is a disease-causing gram-positive bacterial species. Found asymptomatically in the adult gastrointestinal (GI) tract and the female reproductive ...

New Infection and Immunity paper led by @uwmadisonmdtp.bsky.social student Joie Ling on GI colonization by Group B Streptococcus! It describes an adult mouse model of GBS GI colonization & uncovers strain-specific fitness and the role of capsule in persistence. journals.asm.org/doi/10.1128/...

Next Monday, December 8th, Anna Gregory from the Hryckowian Lab will be giving her dissertation defense seminar!

Thank you Erin!

Thank you Vaughn. Tell the 'Burgh I said Hi 😎

Thank you Heidi!

Thank you Mark!

Thank you! I’m honored to receive the Vilas Early-Career Investigator Award and I deeply appreciate the recognition from my colleagues in MMI and from Dean Ahuja. Looking forward to the awesome science this will catalyze 😎

A murine model of adult gastrointestinal colonization by Group B Streptococcus Group B Streptococcus (Streptococcus agalactiae, GBS) is a leading cause of invasive infections in neonates and adults. The adult gastrointestinal (GI) tract represents an understudied site of asympto...

Excited to see Joie Ling's new preprint out! Adult mouse model shows robust GI colonization by Group B Strep without antibiotics. Capsule emerges as a persistence factor in the adult GI.
www.biorxiv.org/content/10.1...

The emerging view on the roles of butyrate in Clostridioides difficile pathogenesis | Infection and Immunity The Centers for Disease Control and Prevention classifies Clostridioides difficile as an urgent threat to the nation’s health, as it causes 450,000 infections, 15,000 deaths, and 1 billion dollars in excess healthcare costs per year in the United States (1, 2). Most C. difficile infections (CDIs) occur in healthcare settings, where CDI is the most common cause of infectious diarrhea (3). Known and suspected risk factors for CDI include antibiotics, proton pump inhibitors, impaired immune function, advanced age, and diet, all of which are associated with dysbiotic gastrointestinal (GI) microbiomes (4–6). Though most CDIs are associated with antibiotic treatment, 22% of individuals with community-acquired CDI have no recent history of antibiotic use. Factors affecting persistent and recurrent CDIs remain poorly defined (7, 8). Despite the morbidity and mortality caused by C. difficile, up to 15% of healthy adults are asymptomatic carriers of toxigenic C. difficile (9), highlighting the gaps in our understanding of C. difficile.

Thrilled to share @alex-dobrila.bsky.social’s new review in Infection & Immunity on how butyrate shapes C. difficile pathogenesis. A must-read for those interested in microbiome–pathogen interactions. 👉 journals.asm.org/doi/10.1128/...

Check out Anna Gregory's great work, recently published in Journal of Bacteriology. Thanks for the shout out, @smitslab.bsky.social 👍