News in Proteomics Research blog post | Lessons learned migrating proteomics to HPC (high performance computing) environments! proteomicsnews.blogs...
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#proteomics #prot-other
Mass Spectrometry-Based Proteomics for Next-Generation Precision Oncology #MassSpectromRev analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10....
Ok this is just insane. Such an amazing application of DVP. Having collaborated on some mitosis related projects I had dreamed of doing exactly this kind of experiment. AI/ML segmentation + laser capture has so many unique applications. This is the tip of the iceberg.
I wrote a very long blog post about AI writing. I hope you'll read it.
meresophistry.substack.com/p/the-mental...
I rebooted my brain by not reading a proteomics paper this afternoon. It is not a proteomics paper, is it?
I learned about proteomics in Yu-Ju Chen’s lab during my grad school in 2018. Most of what I learned came from review papers, articles with in-depth introductions and also maxquant videos.
Thinking about “what if’s”… if I had to move on, I think a good next job would be one where I get to tackle the really big questions, like why does that first batch of pancakes not brown the same as the ensuing batches? People need to know!
Interested in using proteomics in your ECM research? Come hear from 2 excellent researchers on how you can apply this to your work!
March 18th, the link the register is below ☺️
I keep hearing from people who have either listened to or watched this podcast.
They often tell me that my perspective was new to them as they did not realize the fundamental differences between proteomics and transcriptomics.
youtu.be/sGW4cFee1IY?...
Comprehensive coverage of spatial proteomics in The Scientist, highlighting how deep visual proteomics is advancing our understanding of disease. Great to share our perspective alongside another pioneer in the field!
www.the-scientist.com/spatial-prot...
Insights from the #Proteome are becoming increasingly powerful and predictive. Expect low cost #Proteomics to be leveraged in our multimodal future of optimized health, early disease detection, and more targeted, precision medicine.
My latest segment on TechNation Health
🚀 Orbitraps on the move! The #MassSpec community rarely talks about moving Orbitraps, but a new study shows they can collect high-res data while in motion. Have you used an #Orbitrap outside the lab? Let’s start the conversation—share your experience! 🔬⚡ Read more: www.karsa.fi/resources/mo...
#MassSpecHelp #TeamMassSpec
Illumina will enter the Spatial-Omics market in 2026 with Connected Multiomics (ICM) open.substack.com/pub/albertvi...
🚨Amidst all the uncertainty at NIH Welcome Leap just launched an important new $50M program in Women’s Health👩🏻🔬🧠
CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/
Note: full indirects!
Please share widely to support women’s health 🙏🏼
📣📣 first update on our BSPR2025 meeting takingnplace 7-9th july. We reveal our amazing plenary speakers.
@slavov-n.bsky.social will talk about single cell proteomics
@vadim-demichev.bsky.social talking about DIA-NN
@epetsalaki.bsky.social on computational biology focus
Our Deep Visual Proteomics workflow maps protein networks in bladder, prostate, seminal vesicle & lymph node Signet Ring Cell Carcinoma, revealing DNA damage response alterations & immune signatures that could guide therapy choice. Out now in NPJ Precision Oncology! rdcu.be/d8KyK
Hi Skeeps, if you are in the London area and would like me to speak at your university or company, I will be in London on Thursday April 10 and Friday April 11.
Looking for talks that can offer some travel/lodging reimbursement.
Are you funded by #NIH, #NSF or #CDC? Please post any letters or communications you’ve received from these agencies or HHS about restrictions on grant funding, publications etc. I want to catalog all of them for the record. #medsky #episky
DIA-NN 2.0 is released! We consider it the biggest step forward in the history of DIA-NN. On modern LC-MS almost all identifications are now peptidoform-confident, with major improvements e.g. for phospho. Some other cool things too: github.com/vdemichev/Di...
To the amazing government scientists and employees out there who protect our country and people - please hang in there - and thank you. You are appreciated and missed. We can’t wait to see and hear from you!! 🇺🇸
The Mann lab is here now, be sure to follow them.
Also the Bluesky proteomics migration is almost complete!
Do you want to explore the PTMs you identified in your last MS experiment in a fun, interactive way? Try it out on our PTMVision web server at ptmvision-tuevis.cs.uni-tuebingen.de and check out the new publication in JPR at doi.org/10.1021/acs....!
Ion mobility profile for selected ion accumulation, and visualised as part of the total instrument schematic.
You've heard of TIMS, but have you heard of TIMF?
Bruker's new patent describes a Trapped Ion Mobility Filter.
FAIMS selects a narrow range of ions (e.g. 2+ only), but TIMF allows you to exclude ions (1+), and keep ions below or above that mobility (2+ to 5+).
patentscope.wipo.int/search/en/de...
We are here to announce that the British Society for Proteome Research is now fully on BlueSky. This will be our main social network, but we will also post on LinkedIn.
We are excited to interact with the proteomics community and we have lots of exciting news to share.
Proteomics via NGS for UK Biobank will be conducted using the Olink® Explore HT proteomics platform and Ultima's UG 100™ sequencing platform, with the actual sequencing performed at the Regeneron Genetics Center (RGC), one of the world's largest human genetics sequencing and research facilities.
PhDs in biochemistry, structural biology, pharmacology, or similar, located in the US and with strong publication track records and a high motivation to solve Parkinson's, please send CV directly to me at jimhurley@berkeley.edu.
Repost appreciated.
DIA-NN 2.0 release is almost ready, will come with some big news. One is scanning methods support, at the moment doing some tuning of the algorithm using Synchro-PASEF data :) Turns out, 'Q1 information' is really helpful for gaining peptidoform confidence. Likely also channel-confidence in plexDIA.
Happy New Year! Looking to brush up on your LCMS knowledge? Take one of @sciex.bsky.social's ~free~ online training courses after creating a ~FREE~ account:
sciex.com/support/trai...
Label free chemoproteomic profiling of Cys reactive fragments
doi.org/10.1038/s414...
