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Malte Sielaff

@maltesielaff

Postdoc and proteomics researcher at the University Medical Center Mainz.

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28.12.2024
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Latest posts by Malte Sielaff @maltesielaff

Neue Erkenntnisse zur metabolischen Probenstabilität bei Autoimmunerkrankungen Forschende der Universitätsmedizin Mainz zeigen, dass Krankheit und Medikamente die Stabilität von Metaboliten schon vor der Analyse verändern

🚨Paper alert🚨

In a recently published paper, we investigated metabolite ex vivo stability in the context of autoimmunity and medication exposure. Check out the news item on our website for more information and paper link 🙂

#metabolomics
#teammassspec

www.unimedizin-mainz.de/immunologie/...

17.11.2025 12:38 👍 2 🔁 1 💬 0 📌 0

Klobürste>Tee

14.09.2025 06:15 👍 3 🔁 0 💬 0 📌 0

It appears the Tenzer lab was well ahead of the curve with this with their platform:
pubs.acs.org/doi/10.1021/...
This was the solution I found to be most useful.

23.07.2025 11:37 👍 22 🔁 6 💬 0 📌 0

Thanks for clarifying—that makes total sense. An additional quad, at least for filtering out +1s, would definitely be beneficial without any obvious downsides (at least theoretically; though I’m not sure about the practical or technical implications).

28.06.2025 22:13 👍 1 🔁 0 💬 0 📌 0

Isn't ion mobility capable of resolving different charge states, especially +1, too?

28.06.2025 05:05 👍 0 🔁 0 💬 1 📌 0
Preview
Nahostkonflikt (1/4) – Ein Land, zwei Versprechen Podcast-Folge · Was bisher geschah - Geschichtspodcast · 03.06.2025 · 1 Std. 19 Min.

Hörtipp: Ab heute sind alle vier Folgen unseres Vierteilers über den Nahostkonflikt online! Unfassbar schwieriges Thema, vor dem wir großen Respekt hatten, aber wann, wenn nicht jetzt?

podcasts.apple.com/de/podcast/w...

24.06.2025 04:50 👍 241 🔁 38 💬 17 📌 5
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#TeamMassSpec attending the #EuPA2025 conference, don’t miss the presentations from the Tenzer Lab and Immunopeptidomics Platform to learn more about our recent work on #immunopeptidomics, and high-throughput and clinical #proteomics. See you in the beautiful Saint Malo!

16.06.2025 13:18 👍 18 🔁 3 💬 0 📌 0

Gastein, gastaus....

13.06.2025 18:03 👍 3 🔁 0 💬 0 📌 0
Preview
Nach Böhmermann-Sendung: Metal-Band wird von Rechten bedrängt Kampfzone Internet: Die Band Powergame trennt sich von ihrem rechtsdenkenden Gitarristen und wird dafür angefeindet.

"Jemand, der uns jahrelang bewusst verschweigt, dass er rechte Hetze verbreitet und dabei weiß, dass wir das nie akzeptieren würden, war ganz offensichtlich nie unser Freund." Die Metalband Powergame hat ein tolles Statement veröffentlicht:
www.metal-hammer.de/nach-boehmer...

15.05.2025 08:47 👍 1755 🔁 402 💬 52 📌 16

Der Tigginator

10.05.2025 07:19 👍 3 🔁 0 💬 0 📌 0
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Immunopeptidomics is key in personalized cancer immunotherapy. Join our webinar on Apr 24 when Julian Beyrle presents on MAETi: an antibody-free MHC-I workflow using 25K cells + Evotip + DIA-PASEF on timsTOF. Register here: www.evosep.com/webinars/web...
#teammassspec

10.04.2025 13:34 👍 4 🔁 1 💬 0 📌 0

HEY PROTEOMICS PEOPLE! Can you comment here where you learned to do proteomics? I started putting up a survey but based on just the 64 people on our podcast there are too many options for a multiple choice survey effectively. Thank you!

20.03.2025 12:18 👍 11 🔁 5 💬 49 📌 1

Heard Stefan Tenzer's lecture on LC-MS proteomics/immunopeptidomics during my Master's in Mainz. It was eye-opening after a genetics-focused Bachelor’s and led me to his lab for my thesis, and I’m still here as a postdoc. The Brixen Proteomics Summer School was also a key moment!

24.03.2025 09:57 👍 2 🔁 0 💬 0 📌 0
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Abstract submission for #EuPA2025 is open! Find here the link: eupa2025-stmalo.fr/en/program/a... and join us this year in Saint-Malo. We are looking forward to it 🥳

05.02.2025 14:42 👍 11 🔁 8 💬 0 📌 3
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#UteDistler introducing students to #Proteomics at #UPSS2025! Thank you for sharing your knowledge with the new generation of #TeamMassSpec!

03.02.2025 10:58 👍 5 🔁 1 💬 0 📌 0
Preview
Release DIA-NN 2.0 · vdemichev/DiaNN We are excited to announce DIA-NN 2.0, the most significant milestone in the history of DIA-NN development. Key Breakthroughs Proteoform Confidence mode: DIA-NN 2.0 solves the long-standing chall...

DIA-NN 2.0 is released! We consider it the biggest step forward in the history of DIA-NN. On modern LC-MS almost all identifications are now peptidoform-confident, with major improvements e.g. for phospho. Some other cool things too: github.com/vdemichev/Di...

29.01.2025 09:04 👍 150 🔁 39 💬 6 📌 2