RdRp Summit

Many thanks to all who contributed to #RdRpSummit2025 & #ViBioM2025, making these meetings such great platforms for sharing #virus research insights and new #bioinformatics tools! An amazing week of networking & (a bit of) sightseeing in beautiful Lisbon ❤️ @rdrpsummit.bsky.social @evbc.bsky.social

Closing remarks by our lead organizer Ingrida Olendraite :'(
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Alexander Lucaci kicks off the second RdRp Summit consensus statement!

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Spyros Lytras introduces the community project on structure based phylogeny and function prediction!

Thomas Krannich is introducing the community project on benchmarking various aspects of RNA viral discovery.
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Tatiana Demina discussing the initiative on RNA virus journal club!
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Rachid Tahzima's presenting the community project start-up on RNA virus host inference!

Finding new viruses is cool, but Gytis Dudas highlighted everything one can do with viruses we already know!
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You can read about BVFD here doi.org/10.1093/nar/...

Our next keynote speaker, Rachel Kim, introduces us to BVFD. Now we know what the "F" stands for :)
Truly FANTASTIC work!
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Using artificial intelligence to document the hidden RNA virosphere A deep learning algorithm (LucaProt) that integrates both sequence and predicted structural information was employed to identify highly divergent RNA viral “dark matter” in 10,487 metatranscriptomes f...

Lucaprot increases the known diversity of RNA viruses!
www.cell.com/cell/fulltex...

Unravelling the viral dark matter! Our first keynote speaker Xin Hou works with transformer-based AI models for structural prediction, helping detect highly divergent RNA viruses! @xinhou.bsky.social

Our sponsor @peercommunityin.bsky.social is here to talk all about shunting the exploitative publishing culture.

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Introducing PREDICTORix to predict spillover risk to cause potential pandemics.
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Uncovering hundreds of exogenous and endogenous RNA viral RdRp sequences amongst uncharacterised sequences in public protein databases Public databases of protein sequences, such as the National Center for Biotechnology Information (NCBI) Protein repository and UniProt, contain millions of proteins identified in samples from specific...

Searching through uncharacterized proteins to find endogenous viral elements. You can read all about it here- doi.org/10.1101/2024...

Detecting endogenous viral elements in characterized proteins by Katy Brown

Great time in Lisbon so far at @rdrpsummit.bsky.social ! Looking forward to another day of great talks and discussing the future of RNA virus discovery!

+ #ViBioM2025 starting tonight! Can't wait to see lots more friends! 😁😁

Logan: Planetary-Scale Genome Assembly Surveys Life’s Diversity The NCBI Sequence Read Archive (SRA) is the largest public repository of DNA sequencing data, containing the most comprehensive snapshot of Earth’s genetic diversity to date. As its size exceeds 50.0 ...

Wanna read the Logan preprint? You can do it here!
www.biorxiv.org/content/10.1...

Logan's the perfect way to kick-start the second day!
Thank you, Rayan Chikhi @rayanchikhi.bsky.social

Are you ready for day 2 of the #RdRpSummit2025??

SAMEEEEEE!! 🌈🌈

GitHub - dimitris-karapliafis/RdRpCATCH: A community effort to create a shared resource for HMM-based RdRp discovery A community effort to create a shared resource for HMM-based RdRp discovery - dimitris-karapliafis/RdRpCATCH

You can find RdRpCATCH here
github.com/dimitris-kar...

Introducing RdRpCATCH- mining RNA viruses using RdRp HMMs!
Dimitris Karapliafis is here to talk about the community project we took up during the 2023 RdRp Summit!
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We were happy to have you here with us. Definitely looking forward to the MIUVIG2 and happy to brainstorm as a community together! :)

Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes Nature Biotechnology - A workflow using conserved amino acid domains identifies viruses in sequence data at single-cell resolution.

You can read all about their study here -
rdcu.be/elzZI

Laura Luebbert on detecting RNA viruses in single cell data.
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GitHub - OPR-group-BNITM/vimop: A nanopore field sequencing pipeline for virus metagenomic sequencing will soon appear here! A nanopore field sequencing pipeline for virus metagenomic sequencing will soon appear here! - OPR-group-BNITM/vimop

You can find ViMOP here github.com/OPR-group-BN...

You had us at "24 clicks"! 😍😍

Mia Le introduced ViMOP, an easy-to-use bioinformatic pipeline for quick viral surveillance using Nanopore sequencing methods.

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Josué Rodríguez-Ramos on biofractionation methods (both nucleic acid processing & library prep) on soil viromes!

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