Go talk to your Iranian friends, students, postdocs, colleagues. Offer to take on their tasks at work. There is little contact with Iran right now from outside - most of us have no idea what it is like not to have contact with family members while they are being attacked.
Happy to share our new preprint on the mechanism of human tRNA 3' CCA maturation! This project was spearheaded by Bernhard Kuhle in my group, with contributions from many others and a great collaboration with the group of Peter Rehling (UMG). See highlights below!
www.biorxiv.org/content/10.6...
Postdoc positions available in my lab in Aarhus, Denmark on 'Mammalian Nuclear RNA Production and Turnover Systems'. Please get in touch for further information or simply apply here:
mbg.au.dk/en/news-and-...
Sharepic for a seminar at the MPI-IE: Green-blue gradient background. The top left shows the name of the Max Planck Institute for Immunobiology and Epigenetics and its logo. Below is the heading 'MAX PLANCK SEMINAR FREIBURG'. The center displays the lecture title: 'INSPECTING THE ROLES OF CHROMATIN ORGANIZATION IN TRANSCRIPTION REVEALED BY SPATIAL GENOMICS'. The lower left lists the date, time, and venue: 'WED, 11 MARCH 2026, 15:00', 'MPI-IE, LECTURE HALL', 'Stübeweg 51, 79108 Freiburg, Germany'. The lower right shows the speaker's name and affiliation: 'Marcelo Nollmann, Center for Structural Biology, CNRS/INSERM, University of Montpellier, France'.
🤗 Next week, we are happy to welcome Marcelo Nollmann from @cbsmontpellier.bsky.social | @cnrs.fr | @umontpellier.bsky.social.
His lab develops single-molecule and advanced imaging methods to investigate DNA organization, segregation and transcription in multicellular organisms.
Join us at 3pm. ⬇️
Ubiquitin & Friends Fiesta in Vienna, 29-30 April 2026.
Great speakers, small size, a friendly community, perfect for early-career researchers to connect with fellow ubiquitin enthusiasts. Sign up at www.protein-degradation.org/symposium/ and submit abstracts for talks and awards.
#ubfriends26
Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you!
1/n
That time of year again when I make my Mendel impression.
I suppose these are peaches and not peas, and will be furry not wrinkled, and I'm a biochemist not a geneticist, but I'm claiming it anyway.
Super Early Bird deadline Sunday 8 Mar! Save €100
Register for Machines on Genes 2026 ⚙️🧬
Biochemical Society Harden Conference
📍 Heraklion, Crete | 8–11 June 2026 🌊☀️
www.eventsforce.net/biochemsoc/f...
Scientific organisers: Lori Passmore, Dana Branzei & Alessandro Costa
meetings.embo.org/event/26-rna3
To all 3' end (and RNA, in general) enthusiasts. I'm organising a great conference in Oxford 7th-11th Sept with @lapassmore.bsky.social and Christine Mayr. The lineup of speakers is brilliant! Registration closes 4th May. Please consider it!
Excited to share our latest publication on interindividual variation of DNA methylation in human whole blood, spearheaded by the amazing Olivia Grant and co-led with @leo-schalkwyk.bsky.social and Meena Kumari.
link.springer.com/article/10.1...
Auf frischer Tat ertappt: Das #Influenza -Virus stiehlt die Kappe der Wirts-RNA, um sich zu vermehren. Ein Team @mpi-nat.bsky.social hat das Virus zum ersten Mal beim Diebstahl erwischt ;-) www.mpg.de/26214616/030...
1/ 🧵 In our new paper, we show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2. www.cell.com/molecular-ce...
New preprint out!
In this study, we introduce NanoFLex, a strategy that combines #HaloTag variants with #nanobodies -based immunolabeling to enable rapid, OneStep-IF #lifetime #multiplexing. Possible due to SmartSecondaries fused to #HaloTag from @nanotag.bsky.social: www.biorxiv.org/content/10.6...
Portrait shots of two people looking into the camera.
Two Crick group leaders are joining Cancer Grand Challenges teams to tackle big questions in cancer research.
Leanne Li leads a team studying how tumours interact with the nervous system, and Vivian Li joins a @ucl.ac.uk-led team working to rewire cancer cells.
🔗 www.crick.ac.uk/news/2026-03...
Synovial sarcoma is driven almost exclusively by a single oncofusion – SS18-SSX
For years, the assumptions on disease mechanisms were simple:
➡️ SS18-SSX works by hijacking SWI/SNF chromatin remodeling activity
Our new study shows that assumption was wrong 🧵👇
www.biorxiv.org/content/10.6...
Do you work on DNA or RNA protein complexes? 🧬
Come to Machines on Genes this June in Crete! ☀️
Super early discount is ending this Sunday so register now! 😃
I had fun writing this N&Vs on two fascinating new papers on centromere evolution in yeast. If you’re interested in how centromeres adapt yet stay functional, here’s my take. rdcu.be/e6DD0 @nature.com @gautamdey.bsky.social @gsherloc.bsky.social @helsenjana.bsky.social @maxhaase.bsky.social
Predicting protein-protein interactions (PPIs) at proteome scale can take months with co-folding models due to the massive all-vs-all comparisons required.
We are excited to announce FlashPPI, a contrastive learning framework that predicts proteome wide physical interfaces in minutes. 1/🧵
Exciting opportunity to work with an amazing scientist at the cutting edge of DNA repair and telomere biology.
📣 We are looking for new colleagues 🔬🧬🧪
The @lmcb-ucl.bsky.social at University College London @ucllifesciences.bsky.social are looking for outstanding candidates to sponsor for career development fellowships. Fellows would then be assessed for tenured positions at the end of the fellowship term.
I am so grateful to the Blavatnik Family Foundation and the New York Academy of Sciences for this honor. Can’t wait to be back to the lab and celebrate with lab members on this special recognition of their hard work.
I’m thrilled to share that my PhD work has been just published in Cell. After a long and bumpy ride, we uncovered the core function of nuclear speckles -splicing of GC-levelled exons- and traced the evolution of this gene architecture and condensates themselves to amniotes.
Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the thread👇 for the highlights of our findings.
Three @biorxivpreprint.bsky.social preprints on acute depletion of FACT in ES cells. First, from my colleague at Pitt Sarah Hainer's lab 1/ www.biorxiv.org/content/10.6...
Phase separation?
Lovely paper!
Bravo to our neighbours!
We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social
Please get in touch if you have any questions.
www.nature.com/naturecareer...
