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04.02.2026 16:20
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"helping"
We've known for awhile that TACAs are unique markers of cancer.... but targeting them has been challenging. Check out my latest research highlight to find out how Zhou et al. managed it! 😎
Happy New Year! 🍾🥳
Our cover (titled "fast and focused killing") is inspired by the Perspective on FLASH radiotherapy. Happy reading!
www.nature.com/articles/s41...
It seems editing really is a collaborative process 🐈🐈
#purrreviewed
🚨 In light of the #NobelPrize recognizing discoveries in peripheral immune tolerance, our article "Regulatory T cells in the tumour microenvironment" is now free to read.
Discover how #Tregs shape cancer immunity 📖 👇
I am currently at BER waiting to board my flight to Portugal for #ESHAML2025! If you're attending too, I'd love to chat about
@natrevcancer.nature.com, editorial work in general or just to say hi 👋
Happy Thanksgiving to my fellow Canadians! 🍁🦃🥧
Even after finishing a PhD, the advise still resonated.
As an Editor, my advise: read A LOT🤓.
You don't need to reinvent the wheel to write a good paper... but you definitely need to slow down & think. Reading helps you contextualize findings, make good experimental plans & explain your science.
T-ALL is notoriously hard to treat due to the difficulty in distinguishing normal and malignant T cells. Now Fuentes et al. identify the pre-TCR as a biomarker for leukemia-initiating cells and develop a targeted immunotherapy for it.
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In a rare bout of personal news… I’m finally ready to be active on Bluesky again! Outside of my work-hours, I was a little busy planning a wedding with my cats’ dad 🐈🐈.
Photo evidence below 🤭
Our FOCUS issue on #Ageing and Cancer is live!
It features articles on:
- age-induced metabolic reprogramming in cancer progression
- modelling ageing-related cancer evolution
- stromal senescence in age-related cancer
Read it now: http://bit.ly/48uIDB...
Our SEPTEMBER issue is live! 🌤️🍂🌻🍂
It features articles on:
- ER stress responses in anti-cancer immunity
- Regulatory T cells in the TME
- Metabolic adaptations of brain metastasis
- Engineering strategies for nanoparticles
Read it now👇
bit.ly/4mW1JnQ
Put on Tom & Jerry so my lil sidekick Leonard would let me work in peace. She was more into it than I thought she'd be 😹
🤩 It was a pleasure handling this article, and I am equally excited to see it out! Congrats!!!
Exercise induces microbiota to produce formate which in turn enhances CD8+ T cell anti-tumour functionality. 💪 #gains
Check out my research highlight below for more deets 🤓🐛🧫
#REVIEW 🚨
#Nanoparticles can be engineered for targeted delivery of cancer therapies. Gomerdinger, Nabar & Hammond explore how surface chemistry drives delivery, targeting & localization.
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August?! How did that happen?! I am still waiting for summer to arrive in Berlin😫
In any case, this issue is a goodie. Give it a read!! 🤓📖✨
In this Comment, Grünwald & Khokha call for a shift in comprehension of tumour tissue organization; while tumour tissues are heterogeneous, they are not disordered, & instead, propagate their functions via a considerable level of self-organization.
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https://bit.ly/4nZaQ...
I previously volunteered w men returning from prison, where I saw how often adolescent hardships shaped their paths. Incarceration should not make someone undeserving of care & denying medical treatment reflects societal bias + ignorance.
📖⬇️ the barriers to equitable care for those behind bars.
A super cool Perspective highlighting the intersection of metabolic hallmarks of both aging and cancer.
In it, they also explore how population-related metabolic differences associated with longevity may contribute to racial disparities in cancer risk & prognosis.
Give it a read!! 🤓
pictured here is Leonard watching me watch AACR talks 😹
I will absolutely never understand why you would actively choose to turn off spell check on your Word document.😫
Look, we all make mistakes even with spell check on.... but I can tell you without a doubt that it would *defiantely* benefit you to keep it on.
Check out my latest research highlight 👇
While the presence of tertiary lymphoid structures (TLSs) in tumours is often linked with ⬆️response to IO, the maturation status can influence this. Now, Tang et al. uncover tryptophan metabolism as a factor determining TLS maturation status.
Nature Cuteness 🥹
REVIEW🚨
Rodriguez, Cubillos-Ruiz &Co discuss how the #ERstress response affects intratumoural immune cells & highlight the potential of #UPR-targeted interventions to improve cancer outcomes.
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A 'lil wknd readin' for ya 🤓🚨
Tbh, the Coral City Camera is easily my favourite account on bluesky. 😍
Here's some Monday morning reading for you 🤓
Check out my latest research highlight on work from Yingxiao Wang's group at USC.
They engineered EchoBack CAR T cells, an ultrasound activated & genetically modified CAR T cell ("heard immunity" - get it?!) that enables precise spatiotemporal activation + tumour cell killing.
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