ish is a grep-like CLI tool that uses optimal alignment instead of exact matching.
It’s record-type aware, supporting line, FASTA, and FASTQ records.
Built in Mojo as a proof of concept for bioinformatics.
🧵1/5
I was waiting two years to see this out!! The genomic location of bacterial genes is not random!!! Congratulation on the authors (Martin Lercher and Team!). www.science.org/doi/10.1126/...
Alt-Text: A screenshot of a post on X (formerly Twitter) by Senator Mark Kelly (@SenMarkKelly) and a reply from Elon Musk (@elonmusk). Senator Mark Kelly’s post reads: “Just left Ukraine. What I saw proved to me we can’t give up on the Ukrainian people. Everyone wants this war to end, but any agreement has to protect Ukraine’s security and can’t be a giveaway to Putin. Let me tell you about my trip and why it’s important we stand with Ukraine.” The post includes a photograph of a rusted, damaged tank covered in graffiti, parked in a public square. People are walking around the area, and a man wearing a camouflage cap and a brown jacket stands next to the tank. In the background, there is a yellow building with a blue roof and a sign that says “Mariupol.” Elon Musk’s reply to the post says: “You are a traitor.”
“You are a traitor.”
An absurd and insulting thing to say to anyone who posts what Senator Kelly did.
And even more insulting since he served as a U.S. Navy captain and a NASA astronaut.
Kelly was a combat pilot and flew 39 combat missions during Operation Desert Storm in the Gulf War.
1/ We’re nonprofit. We’re independent. We only answer to readers like you.
Investigative journalism isn’t free to do, but thanks to 70K+ members, it’s free to read.
While things are getting sorted over on the other app…
Smash that subscribe button on my NFL starter pack for free agency reactions 👇
go.bsky.app/8RH6KbH
My favorite thing about San Francisco
This National Treasure sequel sucks
The Air Force is stripping Tuskegee Airmen lessons from basic training curriculum because of our White supremacist government.
Put that in a headline.
www.expressnews.com/news/article...
In which we propose (by analogy with variational autoencoders) that the genome instantiates a compressed representation of the form of the organism in a space of latent variables
Really coming down now in Gaithersburg/North Potomac . Streets are getting covered too. Be safe out there
Registration is open! Machine learning and AI approaches to multimodal problems in computational biology. March 3-5, 2025. Hosted by CMU Libraries and DNAnexus.
Hackathon! Register by 2/15: guides.library.cmu.edu/hackathon
"Machine learning and AI approaches to multimodal problems in computational biology."
March 3-5. Hosted by CMU Libraries, @dnanexus.bsky.social + @dcgenomics.bsky.social at @carnegiemellon.bsky.social in PGH (virtual option available)
Tom Brady clearly read the big book of football cliches from cover to cover and memorized it
The reality is that Salesmanship is the differentiation between the two parties.
The Dems couldn't sell dollar bills for 50c
Trump has found his audience and can sell them dollar bills for $5
When everything is a story the algorithm flashes at you as you scroll, you better be selling fast
x
X has ~18m daily USA users. @bsky.app, ~1.5m.
Is it worth 20 MINS a day to proactively recruit and bring your friends, neighbors,relatives, businesses, anyone who is or could be a user, to @bsky.app?
If Bluesky ends up with more users than the others, you destabilize musk, zuck, trump.
Describing a 10 min walk this way is the most American thing I've ever read
It isn't a website but I find github.com/mufeedvh/cod... to be much better with token counting and other features.
How does Texas fall for a fake punt when Georgia’s punter is hurt?
Great! Can’t believe I am just learning this.
I made a little swiss army knife tool for quickly inspecting FASTA/FASTQ sequences, including GC content, codon analysis, reverse complement, and file format conversions: 🖥️ 🧬
42basepairs.com/tools/sequen...
I feel like not enough people know about Quarto for creating documents.
How it works: Write in markdown and use Quarto to convert it to html, pdf, epub, ...
I produce my books with Quarto (web + ebook + print version). But you can also use it for websites, reports, dashboards, ...
quarto.org
For all you Pythonistas out there, if you haven't tried `uv` yet, give it a go. It will blow you mind 🤯 it is essentially `cargo` (from the Rust world) for Python! Amazing it took so long for the ecosystem to get here, but we did. Astral.sh are doing some incredible things, with incredible devs
screenshot of a web form with a new option added and highlighted
OK...that option is now on the form.
I made a starter pack for algorithmic genomics. It's certainly incomplete, but already has a ton of awesome peeps. Let me know if you know people I should add (with a focus on algorithms and data structures in genomics)
go.bsky.app/TRWCnZs
Reminder for newcomers that bioRxiv has Bluesky accounts in every subject category - great way to keep up (please re-skeet) connect.biorxiv.org/news/2023/09...
