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Philip Leftwich

@philipleftwich

Assoc Prof @uniofeastanglia Scientist Biology / Genetics / Rstats

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10.07.2023
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Latest posts by Philip Leftwich @philipleftwich

11.03.2026 20:15 πŸ‘ 5 πŸ” 0 πŸ’¬ 3 πŸ“Œ 0

Do u think they did an equalities audit before deciding on a two-tier workforce because I have some wild guesses about who is most impacted here.

11.03.2026 09:15 πŸ‘ 67 πŸ” 28 πŸ’¬ 1 πŸ“Œ 1
Preview
Reporter - Times Higher Education We're looking for an experienced reporter to cover key issues in UK and global higher education!

We’re hiring! THE is seeking an experienced reporter to lead our coverage of key issues within UK and global HE. Applications close on Tuesday 17 March.
https://careers.timeshighereducation.com/jobs/7312441-reporter

11.03.2026 08:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
SORTEE Webinar: On what makes good sharable and reproducible R code, how to do it, and why it’s good for science For this month's SORTEE webinar, Dr. Dax Kellie from the Atlas of Living Australia will present on good, sharable, and reproducible R code in science

In one week I'll be talking about tips for reproducible R code and why science would love you to try these tips on your own code too πŸ§ͺ😍🌏

It's an online talk, so feel free to watch comfortably from your couch. Hope to see you there!
@sortee.bsky.social #rstats

events.humanitix.com/sortee-webin...

10.03.2026 02:46 πŸ‘ 49 πŸ” 21 πŸ’¬ 1 πŸ“Œ 0

Like dude, just trust me I got this.

09.03.2026 09:51 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

I don't think this is impossible but it requires deconstruction and rebuilding from the ground up.

09.03.2026 08:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Broadly no, because buy-in to the process, critical understanding, and evaluation haven't been fully developed yet

09.03.2026 08:52 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Monday morning Bluesky people, any more thoughts on AI for arts and humanities in HE?

09.03.2026 08:32 πŸ‘ 6 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

On the other hand I've had to become more adaptable - last week we got pen and paper out and drew out our understanding of an experiment. Driven by a desire to get the students away from a computer terminal, but probably something I should have been doing years ago.

09.03.2026 08:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

2) How to read, evaluate and critique the literature. Where does information or evidence come from.

09.03.2026 08:41 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

In teaching my concerns are 1) loss of the struggle - I teach coding - but one of the key learnings from this was actually the development of ordered thinking - without the struggle of learning this doesn't stick now.

09.03.2026 08:39 πŸ‘ 2 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

You asked for Arts & Humanities, but I think these concerns broadly resonate across to the sciences as well e.g. atrophy of critical thinking.

09.03.2026 08:37 πŸ‘ 6 πŸ” 0 πŸ’¬ 3 πŸ“Œ 0

I would watch the hell out of a phyllis and millicent detective agency spinoff!
#callthemidwife

08.03.2026 22:31 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

Thank you all for the kind interest in my aching middle aged body. πŸ‘Œ

08.03.2026 20:02 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The human body is so adaptable.
For example because I didn't manage to go the gym for 2 weeks - my body smartly adapted to the idea that I would never go back and appears to have atrophied all of my muscles πŸ˜“

08.03.2026 17:43 πŸ‘ 830 πŸ” 28 πŸ’¬ 46 πŸ“Œ 3

This is the first formal analysis of the field. So please share it widely - hope this is a tool of wide use to the #genedrive community.

06.03.2026 10:42 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
Four-week timeframe for Β£40m AI research lab divides opinion - Research Professional News Tech advocates celebrate prospect of new UK lab, but β€œextremely tight” application window sparks concern

This is ridiculous but not surprising! Obviously, EPSRC must have people/organisations in mind and I wouldn’t be surprised if they have been in contact with some groups in advance. Some hard questions about why Β£40m is spent as such www.researchprofessionalnews.com/rr-news-uk-r...

07.03.2026 11:30 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Accepted! πŸ₯³
www.biorxiv.org/content/10.1...

06.03.2026 12:34 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

This is the first formal analysis of the field. So please share it widely - hope this is a tool of wide use to the #genedrive community.

06.03.2026 10:42 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Homing gene drive schematic and per-species drive inheritance. (a)Overview showing a CRISPR-Cas9 hominggene drive converting a wild-type allele into a drive allele via inter-homologue gene conversion, alongside alternative outcomes(e.g., retention of the original allele or resistance allele formation).(b)Empirical drive-allele inheritance rates are shown for eachspecies, with each point representing unique crosses (meta-data defined replicates merged).An. coluzziiis a member of theAn.gambiaespecies complex. Point size scales with progeny scored. The colour legend indicates species phylogeny. Confidenceintervals (dark grey lines) reflect precision of the predicted mean (black point); prediction intervals (light grey lines) reflect theexpected range for a new observation

Homing gene drive schematic and per-species drive inheritance. (a)Overview showing a CRISPR-Cas9 hominggene drive converting a wild-type allele into a drive allele via inter-homologue gene conversion, alongside alternative outcomes(e.g., retention of the original allele or resistance allele formation).(b)Empirical drive-allele inheritance rates are shown for eachspecies, with each point representing unique crosses (meta-data defined replicates merged).An. coluzziiis a member of theAn.gambiaespecies complex. Point size scales with progeny scored. The colour legend indicates species phylogeny. Confidenceintervals (dark grey lines) reflect precision of the predicted mean (black point); prediction intervals (light grey lines) reflect theexpected range for a new observation

New pre-print!
Excited to share our new paper β€” the first meta-analysis of CRISPR-based homing gene drives! Analysing nearly one million scored progeny across 42 studies and 10 species.
www.biorxiv.org/content/10.6...

@sebaldv.bsky.social @nikiwind.bsky.social
@eivimeycook.bsky.social

06.03.2026 10:23 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1

And more exciting work on what we do and don't know about making functional #genedrive is about to drop!

04.03.2026 11:32 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Top left cut rates vs homing rates in four different alleles, sequence differences bottom left. Right overall homing rates vary significnantly across different alleles

Top left cut rates vs homing rates in four different alleles, sequence differences bottom left. Right overall homing rates vary significnantly across different alleles

Natural genetic variation can silently undermine gene drive performance.

In our new study, we used a split homing drive in Culex quinquefasciatus and found that target-site heterology of less than 10% reduced homing efficiency by up to 54%.
doi.org/10.1093/gene...

04.03.2026 09:07 πŸ‘ 8 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
University of East Anglia Norwich. 
University brand and logo

University of East Anglia Norwich. University brand and logo

Apparently we've rebranded.
So now I don't have to introduce where I work as "University of East Anglia, it's in Norwich".

26.02.2026 21:26 πŸ‘ 3 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

Good to know

25.02.2026 13:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Job losses at research-intensive universities double in two years - Research Professional News Exclusive: Scale of redundancies revealed branded a β€œdisaster” for UK research capacity

Job losses at UK research-intensive universities double in two years.

Exclusive: Scale of redundancies branded a β€œdisaster”.

www.researchprofessionalnews.com/rr-news-uk-u...

25.02.2026 07:17 πŸ‘ 108 πŸ” 128 πŸ’¬ 8 πŸ“Œ 30
On one end of the spectrum, some teachers are letting students draft their own AI policies. On the other, the most skeptical teachers are using formats like oral exams to restrict the use of AI as much as they can. Schmidt has joined a growing cohort that is trying to find a middle ground.
β€œWhether we liked it or not, the technology was going to be in the hands of our students,” said Kimberly Cooney, an English teacher at Chattahoochee High School in Johns Creek, Georgia. β€œAnd so we could either teach them how to use it ethically and responsibly and teach them to actually augment their thinking, or we could, you know, do nothing.”
One of Cooney’s lesson plans teaches her students to use AI to help brainstorm themes in the Arthur Miller play β€œThe Crucible,” walking them through the technique of structuring AI prompts and then asking them to paraphrase the chatbot’s responses. In another, she shows the class an AI-generated paragraph on an essay assignment and asks students to critique it.

On one end of the spectrum, some teachers are letting students draft their own AI policies. On the other, the most skeptical teachers are using formats like oral exams to restrict the use of AI as much as they can. Schmidt has joined a growing cohort that is trying to find a middle ground. β€œWhether we liked it or not, the technology was going to be in the hands of our students,” said Kimberly Cooney, an English teacher at Chattahoochee High School in Johns Creek, Georgia. β€œAnd so we could either teach them how to use it ethically and responsibly and teach them to actually augment their thinking, or we could, you know, do nothing.” One of Cooney’s lesson plans teaches her students to use AI to help brainstorm themes in the Arthur Miller play β€œThe Crucible,” walking them through the technique of structuring AI prompts and then asking them to paraphrase the chatbot’s responses. In another, she shows the class an AI-generated paragraph on an essay assignment and asks students to critique it.

I feel like there’s a constellation of choices in between these two things.

22.02.2026 18:01 πŸ‘ 93 πŸ” 14 πŸ’¬ 9 πŸ“Œ 9
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The students claiming uni Covid compensation 'for the principle' Dozens of universities have received legal letters over what students say they missed out on during Covid.

This is causing despair in academe. (1) We were forced to close during Covid. We had no choice! (2) We're not service providers like a restaurant, we are institutions of state. (3) We did everything we could. (4) This will cripple current students' education.
www.bbc.co.uk/news/article...

21.02.2026 17:34 πŸ‘ 457 πŸ” 137 πŸ’¬ 64 πŸ“Œ 73
Preview
The Universe and the Neurodiverse What if being 'a bit weird' is actually completely normal? What if sharing our internal struggles is a sign of strength rather than weakness? Award-winning comedian, broadcaster, and author Robin Ince...

Norwich was sold out but there are four returns for tonight

norwichtheatre.org/whats-on/the...

19.02.2026 17:17 πŸ‘ 35 πŸ” 13 πŸ’¬ 1 πŸ“Œ 0
Post image

πŸ“’πŸ“’πŸ“’Lectureships at Bristol!πŸ“’πŸ“’πŸ“’

We're hiring 3 x lecturers (=assistant professor) in Biological Sciences, across the discipline.

Great department, great colleagues, great building, great city

Details here:
www.bristol.ac.uk/jobs/find/de...

18.02.2026 08:16 πŸ‘ 50 πŸ” 82 πŸ’¬ 0 πŸ“Œ 0

Must remember not to login to Bluesky for a dose of optimism 😭

18.02.2026 17:45 πŸ‘ 8 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0