Amy Lock

Single-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed effective therapeutic strategies. This is particularly true...

Happy to announce our preprint going live on BioRxiv! Interested in what’s happening to your fibroblasts’ transcriptomic phenotype once it’s in culture? Look no further!

www.biorxiv.org/content/10.1...

@denklab.bsky.social
#fibroblast #scRNAseq #culture #invitro #keloid #ECM #matrix #mesenchymal

Hi everyone! I’m seeking a new role and would appreciate your support. If you hear of any opportunities, please send me a message! #OpenToWork

About me:
💼 I’m looking for Postdoctoral/Senior Scientist roles.
🌍 London.
⭐ currently work in fibrosis/scarring/pain/itch
⏰ previously worked in biotech

#FluorescenceFriday testing an ATF3 antibody on newly replated immature iPSC-derived sensory neurons. Never get bored of these beautiful images 😍 @denklab.bsky.social

#FluorescenceFriday finally got some keloid scar sections to beautifully show their stromal and sensory neuron architecture! Green = FAP (fibroblasts), white = CD31 (endothelial cells), red = b3-tubulin, blue = DAPI.
@denklab.bsky.social