Tiago Costa

Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

Please RT:📢We are hiring a Post-Doc in Structural Biology to join our multidisciplinary team.

Project: study molecular mechanisms of horizontal gene transfer using cryo-EM and integrative structural biology.

Apply: shorturl.at/ecrVL

#StructuralBiology #CryoEM #Postdoc

Grantham PhD opportunities The Grantham Institute - Climate Change and the Environment invites PhD applications that support projects in some of our priority research areas. In...

🚨 PhD Opportunity in my lab🚨
Harnessing Phage Satellites for Next-Generation Biological Crop Protection
🗓 Deadline: 12 Jan
🔗 Apply: tinyurl.com/425x8ahj
🔗 Project : tinyurl.com/22uanm86
Interested in Structural Microbiology, Phage Biology & SynBio - Apply Now!

Grantham PhD opportunities The Grantham Institute - Climate Change and the Environment invites PhD applications that support projects in some of our priority research areas. In...

🚨 PhD Opportunity in my lab🚨
Harnessing Phage Satellites for Next-Generation Biological Crop Protection
🗓 Deadline: 12 Jan
🔗 Apply: tinyurl.com/425x8ahj
🔗 Project : tinyurl.com/22uanm86
Interested in Structural Microbiology, Phage Biology & SynBio - Apply Now!

The assembly of a hybrid type IV secretion system by a Crohn’s disease-associated Escherichia coli strain - Nature Communications Adherent-invasive strains of E. coli are commonly isolated from patients with Crohn’s disease. Here, the authors show that an AIEC harbours a hybrid Type IV secretion system (T4SS) that mediates pilin...

New paper just out from #OurImperial @tcostalab.bsky.social

The assembly of a hybrid type IV secretion system by a Crohn’s disease-associated Escherichia coli strain.

www.nature.com/articles/s41...

Google's AI Co-Scientist Is Changing the Face of Scientific Research Google's AI co-scientist is proving itself more than a novelty. In two biology studies, it generated exciting ideas that could have taken years of lab work to uncover.

"It's less like pressing a button for an answer and more like mentoring a junior colleague—asking the right questions, pushing back on shallow reasoning, and nudging the system toward sharper insights."

Imperial researchers have discovered how ‘pirate phages’ hijack other viruses to break into bacteria, sharing new genetic material for dangerous traits.

This discovery that could be harnessed to tackle #AMR

Read more ⬇️

www.imperial.ac.uk/news/268213/...

Thrilled to share that two of our papers with @jrpenades.bsky.social & GoogleDeepMind
are now out in @cellpress.bsky.social

1️⃣Microbial piracy: tinyurl.com/yvf6t3b3
2️⃣AI co-scientist mirrors experimental science: tinyurl.com/2dym92kj

@imperialcollegeldn.bsky.social
@imperiallifesci.bsky.social

New study shows how bacteria evolved powered-up propellers | Imperial News | Imperial College London Dr Morgan Beeby’s lab has discovered how some flagella - tiny ‘tail’ propellers used by bacteria for swimming - evolved to be more powerful.

New study shows how bacteria evolved powered-up propellers www.imperial.ac.uk/news/265473/... ... www.nature.com/articles/s41...

Honored to have been chosen for this year’s GlaxoSmithKline Award from @biochemsoc.bsky.social. A big thank you to lab members past and present @imperialsci.bsky.social and @erc.europa.eu @cruk-si.bsky.social @wellcometrust.bsky.social for supporting our work.

BBC Radio 4 - BBC Inside Science, AI in Science: Promise and Peril Google has launched a new AI tool called Co-Scientist. How good is it?

Check out our own Tiago Costa @tcostalab.bsky.social talking about Google's 'AI Co-scientist' on BBC Radio 4 here:

www.bbc.co.uk/programmes/m...

Exciting stuff!

You can listen to Jose Penades @jrpenades.bsky.social interview about #phages and Google's 'AI Co-scientist' on BBC Radio 4 here:
(go to 2:34:15)
www.bbc.co.uk/sounds/play/...

AI mirrors experimental science to uncover a novel mechanism of gene transfer crucial to bacterial evolution AI models have been proposed for hypothesis generation, but testing their ability to drive high-impact research is challenging, since an AI-generated hypothesis can take decades to validate. Here, we ...

With @jrpenades.bsky.social, we challenged Google AI co-scientist to generate hypotheses. In just 2 days, it recapitulated our unpublished, experimentally confirmed mechanism for how cf-PICIs spread between bacterial species! @imperialcollegeldn.bsky.social
tinyurl.com/3byyaeh2

Google’s AI co-scientist could enhance research, say Imperial researchers | Imperial News | Imperial College London An unreleased system designed to assist researchers has the potential to “supercharge science”, according to Imperial researchers.

An unreleased AI system by Google designed to assist researchers has the potential to "supercharge science."

Dr Tiago Dias da Costa and other Imperial researchers were the first to test it, and say it replicated ten years of work in just two days.

www.imperial.ac.uk/news/261293/...

Chimeric infective particles expand species boundaries in phage inducible chromosomal island mobilization Some mobile genetic elements spread among unrelated bacterial species through unknown mechanisms. Recently, we discovered that identical capsid-forming phage-inducible chromosomal islands (cf-PICIs), ...

New work from the lab with @jrpenades.bsky.social! We discovered a biological entity that spreads among different bacterial species by hijacking tails from various phages. This finding has major translational applications due to its broad host range. More news soon!
shorturl.at/kRJqE

Huge congratulations to our Head of Life Sciences Prof Dan Davis @dandavis101.bsky.social
who has been recognised in the 2025 New Year Honours list! 🎖️

Dan receives an MBE for his services to science communication.

#OurImperial

Read more 🔽
imperial.ac.uk/news/259480/...

Cpx-signalling in Yersinia pseudotuberculosis modulates Lipid-A remodelling and resistance to last-resort antimicrobials - npj Antimicrobials and Resistance npj Antimicrobials and Resistance - Cpx-signalling in Yersinia pseudotuberculosis modulates Lipid-A remodelling and resistance to last-resort antimicrobials

Great to see this paper published on Cpx signalling, LPS remodelling and colistin resistance. It is always a pleasure to work with my collaborators and friends @imperialcollegeldn.bsky.social @tcostalab.bsky.social @lukeallsopp.bsky.social and Gerald Larrouy Maumus.
Check at doi.org/10.1038/s442...