Fundamental and Clinical Pharmacology Journal (SFPT)

Medical Cannabis Use in France: An Observational Safety Study Based on the RECANN Registry and the Pharmacovigilance/Addictovigilance System From 2021 to 2024 Introduction The French National Agency for Medicines and Health Products Safety implemented in 2021 a nationwide experimentation for medical cannabis (MC), designed to assess the feasibility of imp...

Now available:
Medical Cannabis Use in France: An Observational
Safety Study Based on the RECANN Registry and the
Pharmacovigilance/Addictovigilance System From 2021
to 2024
#pharmacology #cannabis #pharmacovigilance #addictovigilance @wileyhealth.bsky.social
onlinelibrary.wiley.com/doi/epdf/10....

Immunomodulatory Effects of Hyoscine Butylbromide on Mammalian Macrophages Hyoscine butylbromide (HB), popularly known as Buscopan, is a common anticholinergic antispasmodic used worldwide for gastrointestinal disorders. While the interaction between the cholinergic system ...

Now available:
Immunomodulatory Effects of Hyoscine Butylbromide on Mammalian Macrophages
#fundamental #clinical #pharmacology #buscopan #cytokine #macrophage #antispasmodic #immune #inflammatory @wileyhealth.bsky.social @sfpt-fr.org
onlinelibrary.wiley.com/doi/10.1111/...

SGLT‐2 Inhibitors Use in Hospitalized Patients in France: A Cross‐Sectional Study Background Sodium glucose co-transporter type 2 inhibitors (SGLT2i) were initially developed as glucose-lowering drugs for diabetic patients. A few years after their market authorization in Europe, ...

Now available:
SGLT-2 Inhibitors Use in Hospitalized Patients in France: A Cross-Sectional Study
#clinical #pharmacology #glucose #diabetic #drug #heart #kidney @maxdemo.bsky.social @jbezin.bsky.social @antoinepariente.bsky.social @pernellenoize.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

Atorvastatin‐Associated Liver Injury: Outcome After Statin Rechallenge Background Statin-induced liver injury is frequent and usually not severe. The aim of the present study was to describe the safety of statin rechallenge after atorvastatin-induced liver injury becau...

Now available in Open access:
Atorvastatin-Associated Liver Injury: Outcome After Statin Rechallenge
#fundamental #clinical #pharmacology #liver #statin #drug #treatment #pharmacovigilance @sfpt-fr.org @wileyhealth.bsky.social @jlcracowski.bsky.social

onlinelibrary.wiley.com/doi/10.1111/...

Real‐World Use of Dupilumab in Atopic Dermatitis: Observational Study Results Linked to SNDS Background Dupilumab is reimbursed in France for adult patients with moderate-to-severe atopic dermatitis (AD), in cases of failure, intolerance or contraindication to cyclosporin A (CsA). The Frenc...

Now available:
Real-World Use of Dupilumab in Atopic Dermatitis: Observational Study Results Linked to SNDS
#fundamental #clinical #pharmacology #dermatitis #SNDS #skin #therapy #health #inflammation #epidemiology
@wileyhealth.bsky.social @sfpt-fr.org

onlinelibrary.wiley.com/doi/10.1111/...

Fundamental & Clinical Pharmacology: Vol 40, No 1 Click on the title to browse this issue

January issue now available!
#fundamental #clinical #pharmacology #drug #gabapentinoid #pain #neuropathy #psychoactive #therapy #cancer #zolpidem #cognitive #brain #epidemiology #dose #pharmacogenetics #pharmacovigilance @wileyhealth.bsky.social @sfpt-fr.org
onlinelibrary.wiley.com/toc/14728206...

Now available:
Gabapentinoids and Neuropathic Pain: Evaluation of the Quality of Randomised Controlled Trials: An Umbrella Review
#fundamental #clinical #pharmacology #SFPT #pain #RCT #treatment #gabapentinoid #neuropathy #umbrella @wileyhealth.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...

Residual Effects of Acute and Subchronic Zolpidem Treatments on Attentional Processes in Aged Female Rats Rational Zolpidem, a hypnotic Z-drug commonly prescribed to promote sleep, is predominantly used over the age of 50. In this elderly population, adverse behavioral disturbances, impaired driving per...

Now available in Open Access:
Residual Effects of Acute and Subchronic Zolpidem Treatments on Attentional Processes in Aged Female Rats
#fundamental #clinical #pharmacology #SFPT #Wiley #treatment #rat #cognitive #pharmacokinetic #behaviour #drug
onlinelibrary.wiley.com/doi/10.1111/...

December issue now available!
#fundamental #clinical #pharmacology #SFPT #drug #rat #diabetic #toxicity #prostacyclin #ECM #fibrosis #immune #cell #LPS #DOAC #pharmacovigilance #ASA #probiotic #chemotherapy #dose #BCP #anxiety
@wileyhealth.bsky.social

onlinelibrary.wiley.com/toc/14728206...

Editorial for the Fibrosis and antifibrotic drugs article collection now available!
onlinelibrary.wiley.com/doi/10.1111/...

More information about the article collection here: onlinelibrary.wiley.com/page/journal...
#SFPT #Wiley #pharmacology #fundamental #clinical #fibrosis #drug #antifibrotic

Les 23 et 24 mars 2026 auront lieu à Tours les Disputatio, joutes oratoires pharmacologiques organisées par la SFPT

sfpt-fr.org/les-disputat...

#pharmacology #pathology #innovation #clinical #SFPT #disputatio

Impact of Direct Oral Anticoagulant Uptake on Hospitalizations for Stroke/Transient Ischemic Attack, Intracranial Hemorrhage, and Gastrointestinal Bleeding in Individuals With Atrial Fibrillation: A P... Background Direct-acting oral anticoagulants (DOACs) have largely replaced warfarin for stroke prevention in patients with atrial fibrillation, yet their population-level impact on health outcomes a.....

Now available in Open Access:
Impact of Direct Oral Anticoagulant Uptake on Hospitalizations for Stroke/Transient Ischemic Attack, Intracranial Hemorrhage, and Gastrointestinal Bleeding in Individuals With Atrial Fibrillation: A Population-Based Study
onlinelibrary.wiley.com/doi/10.1111/...

Fundamental & Clinical Pharmacology: Vol 39, No 5 Click on the title to browse this issue

FCP October issue now available!

#SFPT #pharmacology #fundamental #clinical #drug #rat #statin #cholesterol #heart #repurposing #pharmacokinetic #antibiotic #cancer #anxiety #brain #therapeutic #neural #cisplatin #genitourinary #integrin #cell

onlinelibrary.wiley.com/toc/14728206...

Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology‐Driven Delivery Strategies This review highlights the integration of drug repurposing and nanotechnology-driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidi...

Now available in Open Access:
Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology-Driven Delivery Strategies

#pharmacology #SFPT #Wiley #clinical #fundamental #statin #antifungal #drug #candidiasis #nanotechnology #treatment

onlinelibrary.wiley.com/doi/10.1111/...

FCP August issue now available!

#SFPT #Wiley #pharmacology #fundamental #clinical #psychiatry #oncology #pharmacovigilance #disease #liver #cancer #cell #drug #treatment #vitamin #inflammation #brain #gene #kidney #paediatrics #cannabinoids #signaling

onlinelibrary.wiley.com/toc/14728206...

Now available in Open Access: Psilocybin as Transformative Fast-Acting Antidepressant: Pharmacological Properties and Molecular Mechanisms
onlinelibrary.wiley.com/doi/10.1111/...
opens our article collection focusing on Innovations in pharma for psychiatry :
onlinelibrary.wiley.com/page/journal...

SFPT 2025 annual meeting abstracts available:

onlinelibrary.wiley.com/toc/14728206...

#SFPT #Wiley #fundamental #clinical #pharmacology #drug #therapeutic #pharmacogenetic #toxicology #pharmacoepidemiology #medication #cardiovascular #renal #disease #methodology #neurology #oncology #addiction

Fundamental and clinical pharmacology for a new psychiatry Click on the article title to read more.

Editorial for Innovation in pharmacology in psychiatry article collection now available!

#SFPT #Wiley #pharmacology #innovation #fundamental #clinical #psychiatry #brain #psychopharmacology #treatment #depression #neuropharmacology #preclinical #esketamine

onlinelibrary.wiley.com/doi/10.1111/...

Vitamin D lacks efficacy: A re‐analysis of a systematic review using the REB method Background The results of randomized controlled trials (RCTs) evaluating the effect of vitamin D on the prevention of acute respiratory tract infections (RTIs) are conflicting. The aim of this study...

Now available:

Vitamin D lacks efficacy: A re-analysis of a systematic review using the REB method

#SFPT #pharmacology #clinical #fundamental #vitamin #REB #review #pulmonary #RCT #RTI

onlinelibrary.wiley.com/doi/10.1111/...

Angiotensin II Type 1 Receptor Blocker Usage Prevents Oxidative Stress and Muscle Dysfunction in HIV Background We aimed to elucidate the role of Angiotensin II type 1 receptor (AT1R) blocker usage in muscle wasting and dysfunction related to HIV. Research Design and Methods Appendicular skeletal...

Now available in Open Access:

Angiotensin II Type 1 Receptor Blocker Usage Prevents Oxidative Stress and Muscle Dysfunction in HIV

#SFPT #Wiley #pharmacology #cardiovascular #clinical #fundamental #HIV #angiotensin

onlinelibrary.wiley.com/doi/10.1111/...

Fundamental & Clinical Pharmacology: Vol 39, No 3 Click on the title to browse this issue

FCP June issue now available!

#SFPT #pharmacology #clinical #fundamental #drug #pharmacogenetics #pharmacovigilance #cardiovascular #inflammation #brain #metabolism #tumour #cancer #oncopharmacology #pulmonary #rat

onlinelibrary.wiley.com/toc/14728206...

Fundamental & Clinical Pharmacology: Call for Papers - Innovations in pharmacology for psychiatry Submission deadline: Saturday, 24 April 2027

Call for papers! 📣
Innovations in pharmacology for psychiatry Article collection

#SFPT #pharmacology #Wiley #psychiatry #innovation #drug #therapeutic #clinical #preclinical #brain #fundamental #neuropharmacology

onlinelibrary.wiley.com/page/journal...

Fundamental & Clinical Pharmacology: Vol 39, No 2 Click on the title to browse this issue

FCP March issue now available!
onlinelibrary.wiley.com/toc/14728206...

#SFPT #pharmacology #cancer #drug #ketamine #clinical #patient #toxicity #pharmacokinetics #parkinson

Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study Introduction (Pre-)clinical studies have not ruled out a potential risk of second primary cancer (SCP) under the effect of some new androgen receptor pathway inhibitors (ARPIs), especially enzalutam...

Now available in Open Access:
Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study

#SFPT #cancer #pharmacology #hormonal #therapy #prostate #Wiley

onlinelibrary.wiley.com/doi/10.1111/...

Fundamental & Clinical Pharmacology Call for Papers Drug repositioning

FCP- Call for papers!
Drug repositioning article collection!
#SFPT #pharmacology #drug #drugrepositioning #callforpapers

onlinelibrary.wiley.com/page/journal...

available in open access!

Detection of ketamine in the oral fluid of drivers in northeastern France during the years 2020–2023 Background and Objectives Ketamine is a psychoactive substance used for its stimulant and hallucinogenic properties. As the use of ketamine may lead to impaired driving, we aimed to assess the occur...

Now available:
Detection of ketamine in the oral fluid of drivers in northeastern France during the years 2020–2023
onlinelibrary.wiley.com/doi/full/10....

#ketamine #driver #addiction #drug #pharmacology #pharmacotoxicology #sfpt

Real‐world interpatient variability in the pharmacokinetics of levetiracetam Background Levetiracetam (LEV) is an antiepileptic drug (AED) used to treat a variety of seizures in adult and pediatric populations. It is an ideal AED due to its favorable pharmacokinetic (PK) and.....

Now available in Open access:
Real-world interpatient variability in the pharmacokinetics of levetiracetam
onlinelibrary.wiley.com/doi/full/10....

#pharmacology #pharmacokinetics #levetiracetam #drug #therapeutic #monitoring #sfpt

Fundamental & Clinical Pharmacology: Vol 39, No 1 Click on the title to browse this issue

FCP February issue now available!
onlinelibrary.wiley.com/toc/14728206...
@WileyHealth

#pharmacology #cancer #oncology #dosing #clinical #pharmacokinetics #drug #repurposing #breastfeeding #bodymassindex #cell #SFPT

SFPT annual meeting 2025 - 24-26th of June
Abstract submission deadline extended to 12th of January!

www.congres-sfpt.fr/abstract.asp...

#SFPT #pharmacology #medication #cardiovascular #oncology #pharmacoepidemiology #pharmacovigilance #pharmacogenetic