A cartoon showing a middle-aged mouse at an office desk, remembering (in a thought bubble) a childhood birthday, with his parent bringing him a cake with a single candle; cartoon glial cells are controlling a cable that links to his early memories. Infantile amnesia is the global loss of episodic and contextual memories formed in early life. Image credit: Birte Doludda
Infantile #amnesia limits our recall of early-life memories, but what is its cellular basis? @tjryan.bsky.social &co reveal that transient #microglial activity during postnatal development regulates infant #memory persistence & retrieval in mice @plosbiology.org 🧪 plos.io/4a0SoGH