Phillip Cleves's Avatar

Phillip Cleves

@pcleves

Symbiosis, cell and developmental biology, and corals. Assistant Professor in Genetics, Genomics, Evolution, and Development at UC-Berkeley.

945
Followers
1,000
Following
11
Posts
29.10.2023
Joined
Posts Following

Latest posts by Phillip Cleves @pcleves

Post image

Even more excited — our paper is featured on the cover of Science Advances!

Huge thanks to @alexandrejan.bsky.social who took this incredible photo of a ctenophore (aka comb jelly) and the editors.

Here’s the cover 👇

www.science.org/doi/10.1126/...

04.03.2026 20:54 👍 87 🔁 24 💬 3 📌 2

Lab is up and running! Stop by and say hi!

03.03.2026 04:57 👍 2 🔁 0 💬 0 📌 0
Preview
Efficient genome editing using CRISPR–Cas9 in reef-building corals - Nature Protocols In this protocol, the authors present straightforward and efficient methods to genetically modify corals and study gene function throughout various life-history stages using CRISPR–Cas9-based mutagene...

To increase the use of gene editing in corals, we have made a comprehensive methods paper describing the protocol. We hope this helps the field of functional genetics in corals. www.nature.com/articles/s41...

02.03.2026 17:54 👍 45 🔁 17 💬 2 📌 0
Video thumbnail

🦋✂️🧬 🧪 New preprint! Led by @donyaniyaz.bsky.social CRISPR‑Cas9 knockouts of ABCG transporters across butterflies & moths reveal how pigment pathways shape color during development. #CRISPR #Lepidoptera #pigmentation
Feedback welcome 👩‍🔬
www.biorxiv.org/content/10.6...

27.02.2026 16:52 👍 24 🔁 15 💬 1 📌 0
Preview
Molecular and Cell Biology of Symbiosis | Marine Biological Laboratory This is an immersive research-based course designed to teach basic concepts, open research questions, and facilitate state-of-the-art experimental approaches in symbiosis research.

It is happening again! Consider taking our course on the Molecular and Cell Biology of Symbiosis at
@mblscience.bsky.social. Application deadline March 4th! www.mbl.edu/education/ad...

26.02.2026 17:08 👍 4 🔁 5 💬 0 📌 0
Santa Cruz Developmental Biology Meeting

Registration is OPEN for the 2026 Santa Cruz Meeting on Developmental Biology!!! Please spread the word!

@mads100tist.bsky.social @socdevbio.bsky.social @bsdb.bsky.social @xenbase.bsky.social @isdb.bsky.social @devbiol.bsky.social @the-node.bsky.social

scdb2026.sites.ucsc.edu

10.02.2026 20:12 👍 46 🔁 39 💬 1 📌 4
Post image

New preprint from our big collaborative evolution experiment in 9 whole lakes in Alaska, written by McGill grad student @lucaseckert.bsky.social
www.biorxiv.org/content/10.6...
What happens if you put a mixture of multiple source populations together to complete & evolve in multiple new lakes?

05.02.2026 20:41 👍 56 🔁 22 💬 1 📌 2
Post image

New #GENETICS report from @pcleves.bsky.social et al. shows the use of a simple electroporation protocol to introduce various genetic constructs into Aiptasia zygotes, a small sea anemone and an emerging model to study coral biology. buff.ly/5aQpQ1S

29.12.2025 14:02 👍 6 🔁 2 💬 0 📌 0
Santa Cruz Developmental Biology Meeting

The 2026 Santa Cruz Developmental Biology Meeting website is LIVE!!! Go see the incredible list of scientists who will be speaking at the meeting next summer! (...and check the site early next year for info on registration and abstract submission.)

scdb2026.sites.ucsc.edu

19.12.2025 20:38 👍 26 🔁 17 💬 0 📌 6
Preview
Epithelial cell extrusion underlies starvation-induced cell loss in a sea anemone Epithelia likely predate the last common animal ancestor, yet the evolutionary origin and environmental regulation of epithelial remodelling remain poorly understood. Here, we show that extensive, sta...

Beautiful work. www.biorxiv.org/content/10.6...

16.12.2025 14:46 👍 0 🔁 0 💬 0 📌 0

Nice congrats!

28.10.2025 00:39 👍 1 🔁 0 💬 0 📌 0
Preview
An endosymbiotic origin of the crimson pigment from the lac insect | PNAS Symbioses with microorganisms expand the genetic and metabolic repertoire of many insects. The lac insect Kerria lacca (Hemiptera: Sternorrhyncha) ...

www.pnas.org/doi/abs/10.1...

22.10.2025 02:22 👍 0 🔁 0 💬 0 📌 0

New paper from the lab. Molecular characterization of the symbiont-containing organelle with proteomics and reverse genetics in Aiptasia and coral.

13.10.2025 22:02 👍 8 🔁 1 💬 0 📌 0
Post image

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...

24.09.2025 15:12 👍 228 🔁 106 💬 4 📌 10
Post image

How do microbes become permanent partners? 🌊🔬🦠 Check out our new study published in Current Biology showing how cyanobacterial genomes evolve step-by-step into endosymbionts of diatoms. www.sciencedirect.com/science/arti...
@currentbiology.bsky.social @mehrshmali.bsky.social

30.08.2025 13:53 👍 120 🔁 51 💬 4 📌 5
Post image Post image Post image

Before today, I would have never known it was possible to run DNA extractions and PCR without a lab. Who knew that a molecular bio bento box could facilitate bringing the lab into the field? I’m very excited to see how our hornwort Cyanobacteria community sequencing turns out later this week.

21.08.2025 03:05 👍 10 🔁 1 💬 1 📌 0
Post image

We're Hiring! Assistant Professor of Immunology and Molecular Medicine in MCB. Learn more and apply online:
aprecruit.berkeley.edu/JPF05096

20.08.2025 22:45 👍 21 🔁 31 💬 0 📌 2
Video thumbnail

This surprisingly relaxing footage is from SIX MILES under the ocean – and it’s the deepest ecosystem yet discovered

31.07.2025 15:38 👍 14186 🔁 3420 💬 431 📌 525

Congrats!

01.07.2025 19:37 👍 1 🔁 0 💬 1 📌 0
This is figure 3, which shows amniote footprints.

This is figure 3, which shows amniote footprints.

A paper in Nature reports the discovery of fossilized claw prints thought to belong to an amniote on a slab of rock from Australia dated to about 356 million years ago, suggesting that the origin of amniotes is earlier than expected. go.nature.com/4jm5XTP #Paleosky 🧪

26.05.2025 01:46 👍 40 🔁 7 💬 0 📌 0
Preview
Molecular and Cell Biology of Symbiosis | Marine Biological Laboratory This is an immersive research-based course designed to teach basic concepts, open research questions, and facilitate state-of-the-art experimental approaches in symbiosis research.

It is happening again! Consider taking our course on the Molecular and Cell Biology of Symbiosis at
@MBLScience. We extended the deadline for
applications to Apr 14, 2025. www.mbl.edu/education/ad...

02.04.2025 16:38 👍 6 🔁 4 💬 0 📌 0
Preview
The Cleves Lab The Cleves Lab researches the molecular, cellular, and developmental basis of how intracellular beneficial microbes invade and persist in animal cells to form symbiosis. They use ecologically critical...

It’s live! Check out the Cleves Lab website and learn how the lab uses ecologically relevant cnidarian models to gain key insights into how microbial symbiosis and its breakdown impact animal biology and health, driving new coral conservation efforts. 🪸🎉

@pcleves.bsky.social
www.cleveslab.org

28.03.2025 16:04 👍 9 🔁 4 💬 0 📌 0
Post image

Save the date 📅: The PhD Summer School on Host-microbe Symbioses is taking place from 6-19 of July in Oeiras, Portugal.
Registration is opening soon!
Learn more 👉 gimm.idloom.events/phd-summer-s...

@gimmfoundation.bsky.social @moorefound.bsky.social
@crc1182.bsky.social #CIFAR #CBR

05.02.2025 17:27 👍 13 🔁 11 💬 1 📌 2

#protistsonsky

21.01.2025 16:03 👍 10 🔁 3 💬 0 📌 0
Video thumbnail

Neural crest of Xenopus embryos labelled with nuclear GFP

11.12.2024 20:12 👍 86 🔁 14 💬 1 📌 1

Lets put this back in the feed and see if there is anyone else who who'd like to be added.

We are getting your future grad students ready, and plan on writing a book one day…maybe.

go.bsky.app/RnHK313

06.12.2024 22:58 👍 19 🔁 14 💬 5 📌 0

I would love to be added

08.12.2024 14:34 👍 0 🔁 0 💬 1 📌 0
The allure of fluorescence in the ocean
The allure of fluorescence in the ocean YouTube video by MBARI (Monterey Bay Aquarium Research Institute)

A video we made at @mbarinews.bsky.social explaining some functions of #fluorescence in the ocean, and how #bioluminescence is different… but related.
🦑🧪🌊
m.youtube.com/watch?v=whbe...

02.12.2024 15:07 👍 55 🔁 20 💬 2 📌 3
Preview
Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies Intracellular bacterial pathogens are distinctive tools for fighting cancer, as they can proliferate in tumors and deliver therapeutic payloads to the…

I'm pumped to finally share our lab's first publication!
Microbiology and cancer are deeply intertwined, and this is our first foray into the cancer field. We asked: how do bacteria activate innate immunity in tumors to elicit anti-cancer responses?
www.sciencedirect.com/science/arti...

02.12.2024 23:31 👍 64 🔁 11 💬 8 📌 1
Video thumbnail

Thrilled to present our latest BioRXiv on brain/body interactions during defensive freezing behaviour! (www.biorxiv.org/content/10.1...). You might think that a frozen animal has, well, frozen muscle activity, right? Wrong! Underneath the still surface of a fly, something in the legs is beating… 🧵

02.12.2024 09:57 👍 175 🔁 57 💬 5 📌 17