George O'Toole (he/him/his)'s Avatar

George O'Toole (he/him/his)

@geiselbiofilm

Elmer R. Pfefferkorn, PhD, Professor of Microbiology & Immunology at the Geisel School of Medicine, EiC of the Journal of Bacteriology; Bacterial Biofilms, Surface Sensing, c-di-GMP Signaling, Polymicrobial Communities & Gut Microbiota in Cystic Fibrosis

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16.01.2025
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Latest posts by George O'Toole (he/him/his) @geiselbiofilm

ASM figures are pictured across images, representing timeline of ASM's history.

ASM figures are pictured across images, representing timeline of ASM's history.

125+ years of microbial science history, all in 1 place ๐Ÿงซโœจ Explore ASMโ€™s new virtual exhibit featuring archives, stories and milestones that shaped our global community. Start exploring: asm.social/2Qk

07.03.2026 00:12 ๐Ÿ‘ 4 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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New in JB: Schmidt, Thormann study the polar landmark protein FimV of P. putida & find it binds peptidoglycan, swimming & localization of the Che system, participating in different functions than homologs in other microbes.
journals.asm.org/doi/10.1128/...
@asm.org #JBAacteriology

06.03.2026 14:07 ๐Ÿ‘ 2 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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New In JB: Phale, Kasarlawar et al. review the unusual traits of Pseudomonas bharatica CSV86T, an organism that they offer as useful for both bioremediation and up-cycling aromatic compounds.
journals.asm.org/doi/full/10....
@asm.org #JBacteriology

05.03.2026 19:28 ๐Ÿ‘ 4 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Thanks for the hard work!!

05.03.2026 13:10 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Joanna Goldberg, Michael D. L. Johnson and Vaughn Cooper

Joanna Goldberg, Michael D. L. Johnson and Vaughn Cooper

ASM board members in front of the Capitol Building in Washington, D.C.

ASM board members in front of the Capitol Building in Washington, D.C.

Michael D. L. Johnson and Joanna Goldberg standing in front of a NASA space suit

Michael D. L. Johnson and Joanna Goldberg standing in front of a NASA space suit

ASM board members spent yesterday on Capitol Hill meeting with members of Congress and their staff, emphasizing the need for stable, full-year funding for science and public health agencies. See ASMโ€™s FY2027 funding requests: asm.social/2Q4 #ASMAdvocacy

05.03.2026 12:29 ๐Ÿ‘ 15 ๐Ÿ” 3 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
Interaction of C. glabrata wild type and C. albicans yeast-locked efg1ฮ”ฮ”/cph1ฮ”ฮ” mutant cells with macrophages.

Interaction of C. glabrata wild type and C. albicans yeast-locked efg1ฮ”ฮ”/cph1ฮ”ฮ” mutant cells with macrophages.

Should I stay or should I go? Research in #mBio suggests the fungus Candida glabrata may actively prolong the part of its life spent inside macrophages, which could contribute to immune evasion, antifungal resistance and potential recurrence of infection. asm.social/2Q2

04.03.2026 19:37 ๐Ÿ‘ 9 ๐Ÿ” 5 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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New in JB: Downing, Nayak et al. detail differences in acetoclastic methanogenesis between Methanosarcina spp. and Methanothrix spp. leveraging a combination of comparative genomics and molecular genetics.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

04.03.2026 15:53 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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New in JB: Hartzler, Metskas et al. review recent information about ฮฑ-carboxysome structure, mechanism, and assembly through the lens of cryo EM and tomography. A really exciting topic - one of my favorite areas to include in my grad course!
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

03.03.2026 14:47 ๐Ÿ‘ 7 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Very happy for my former PhD student Jarrod Smith, seen here in his new lab. He is now an Asst Professor of Medicine & Microbiology/Immunology at Dartmouth! It is great to have him back. His lab uses zebrafish as a model to study gut microbiota.
graduate.dartmouth.edu/mcb/people/j...

02.03.2026 22:35 ๐Ÿ‘ 25 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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Our newest paper by Sarvesh Surve, a PhD student in the lab, explores the culturome of the regions of the gut for persons with CF. We see clear differences from healthy controls, esp. in the mucosal samples.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

02.03.2026 22:22 ๐Ÿ‘ 9 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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New in JB: Smith, Unnikrishnan et al. connect daptomycin sensitivity to the staphylococcal type VII secretion system protein EsxC via changes in the membrane, linking pathogenesis to Abx sensitivity.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

02.03.2026 15:02 ๐Ÿ‘ 8 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Thanks also to our colleagues in DartCF for their help analyzing this big data set.

27.02.2026 20:45 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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DEADLINE APPROACHING!

Apply to Molecular and Cell Biology of Symbiosis by March 4. This immersive four-week course is designed to teach basic concepts and and facilitate state-of-the-art experimental approaches in symbiosis research.

๐Ÿ”—More info here: go.mbl.edu/symbiosis

26.02.2026 22:09 ๐Ÿ‘ 12 ๐Ÿ” 5 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Phage Therapy Coordination Network | ASM.org ASM Health is unlocking bacteriophage therapies for antimicrobial resistance (AMR) through coordinated access and regulatory approvals.

Phage therapy offers a powerful tool against AMR infectionsโ€”but only if we move from isolated cases to coordinated systems. The first initiative of the ASM Health Unit, led by Colleen Kraft and Dev Mittar, will tackle this. Delighted by this scientific leadership, join us!

asm.org/about-asm/as...

27.01.2026 17:52 ๐Ÿ‘ 40 ๐Ÿ” 17 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
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Excited about a recent paper from Bassam el Hafi, a recently graduated PhD student, & Fabrice Jean Pierre leveraging 4,200 respiratory microbiomes from CF (pre- and post-ETI), and testing one of the hypotheses that arose from this analysis.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

27.02.2026 20:19 ๐Ÿ‘ 8 ๐Ÿ” 4 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 2
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JB Editor's Pick: Westlake, Criss et al. show that the neuroendocrine hormone norepinephrine depresses the Fur operon of Neisseria gonorrhoeae, perhaps via direct demetalation of Fur, resulting in increased survival of this microbe.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

27.02.2026 15:11 ๐Ÿ‘ 4 ๐Ÿ” 2 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0
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Kaitlyn Webster joined the MBL's Frontiers in Reproduction (FIR) course in 2019. What she learned in FIR enabled her to develop an entirely new research program, and eventually led her to a 2025 Lโ€™Orรฉal For Women in Science Fellowship.

๐Ÿ”— Full story here: go.mbl.edu/take5-webster

26.02.2026 19:24 ๐Ÿ‘ 3 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Shawna Pratt, a postdoc in the lab, is part of the crew teaching a short course titled "Bacterial Nucleotide Second Messenger Signaling in Bacteria" sponsored by UNU-Biolac and held at the Universidad Nacional de La Plata. Shawna gave a lecture and ran lab workshops on a variety of biofilm assays.

26.02.2026 21:11 ๐Ÿ‘ 12 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social

Please get in touch if you have any questions.
www.nature.com/naturecareer...

25.02.2026 22:25 ๐Ÿ‘ 51 ๐Ÿ” 54 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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New in JB: Adams & El-Halfawy review how various chemicals produced at the site of infections, including those made by the host & bacteria, impact Abx responsiveness. Learning about such mechanisms could help develop new Abx strategies.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

26.02.2026 15:47 ๐Ÿ‘ 2 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Preview
From Lab to Literature: A Conversation with Dr. Steffanie Strathdee | ASM Online Learning Center Join us for an exclusive interview with Steffanie Strathdee, Ph.D., Harold Simon Distinguished Professor in the Department of...

Join us on March 9 at 1 p.m. ET for an exclusive interview with Steffanie Strathdee, Ph.D., (UC San Diego) on her memoir "The Perfect Predator"โ€”a gripping story of her race save her husband from a deadly superbug using bacteriophage therapy. Register now:
asm.social/2PD

26.02.2026 12:18 ๐Ÿ‘ 6 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Proteolytic Activation of Influenza A Virus Hemagglutinin in the Airway Epithelium
March 4, 2026
Michael Vahey, Ph.D., Washington University, St. Louis, Missouri
Martin Schwemmle, Ph.D. (moderator), Editor, Journal of Virology, University of Freiburg, Germany
Stacey Schultz-Cherry, Ph.D. (host), Co-Editor in Chief, Journal of Virology,, St. Jude Children's Research Hospital

Proteolytic Activation of Influenza A Virus Hemagglutinin in the Airway Epithelium March 4, 2026 Michael Vahey, Ph.D., Washington University, St. Louis, Missouri Martin Schwemmle, Ph.D. (moderator), Editor, Journal of Virology, University of Freiburg, Germany Stacey Schultz-Cherry, Ph.D. (host), Co-Editor in Chief, Journal of Virology,, St. Jude Children's Research Hospital

Last chance! ๐Ÿ“ข Join the Journal of Virologyยฎ Seminar on influenza A hemagglutinin activation in airway epithelial cellsโ€”featuring Michael Vahey, Ph.D.

๐Ÿ“… March 4 | 11 a.m. ET

๐Ÿ”— Register: asm.social/2Py

25.02.2026 16:49 ๐Ÿ‘ 3 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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DEADLINE APPROACHING!

Apply to Zebrafish Development and Genetics by March 2. This two-week course is designed advanced graduate students, postdoctoral fellows, and independent investigators.

Financial aid is available.

๐Ÿ”—More info here: go.mbl.edu/zebrafish

25.02.2026 18:07 ๐Ÿ‘ 10 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
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The MBL Annual Fund that powers the people, programs, and discoveries at the heart of our work every day. Gifts to the Annual Fund provide flexible support for innovation across the MBL community. Join us in advancing the science that shapes our future.

๐Ÿ”—mbl.edu/give

25.02.2026 14:30 ๐Ÿ‘ 6 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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JB Editor's Pick: Westerman, Elfenbein et al. explore the mechanisms of sulfite stress resistance via their ability to detoxify these compounds, a key pathway for Salmonella in the host and when exposed as a food additive.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

25.02.2026 12:21 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Advancing Microbial Solutions That Enhance Sustainable Approaches to Environmental Challenges
Advancing Microbial Solutions That Enhance Sustainable Approaches to Environmental Challenges YouTube video by American Society for Microbiology

Environmental microbiology connects climate change, the bioeconomy, and One Healthโ€”but not in the way most people think. Microbes control carbon, enable sustainable technologies, and shape health across ecosystems. Brian Badgley, Ph.D., explains why that matters now. www.youtube.com/watch?v=0fXq...

24.02.2026 20:05 ๐Ÿ‘ 7 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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JB Editor's Choice: As part of our History of Microbial Model Systems series, Snow, Hatzios & Salama discuss the first bacteria designated a class I carcinogen, Helicobacter pylori.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

24.02.2026 12:24 ๐Ÿ‘ 9 ๐Ÿ” 5 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme?
Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues.
Apply by 16 MAR
www.nature.com/naturecareer...

24.02.2026 09:45 ๐Ÿ‘ 36 ๐Ÿ” 48 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
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JB Editor's Pick: Iglesias, Mongiardini et al. show that loss of the Tad pili of B. diazoefficiens results in enhanced biofilm formation - they propose a regulatory role, perhaps via cdG, for Tad impacting biofilms in this bug.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

23.02.2026 22:54 ๐Ÿ‘ 6 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Veronica Garcia

Veronica Garcia

From leading R&D in biotech to working for NASA, Veronica Garcia, Ph.D., Scientific Director of the ASM AEM unit, shares her love for microbes and how the AEM unit will advance science-driven solutions in climate change, water systems & food production. asm.org/podcasts/mtm...

23.02.2026 15:36 ๐Ÿ‘ 3 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0