Jonay Garcia-Luis

SMC and recombination enthusiasts: we updated our work describing the loop extrusion properties of budding yeast condensin and its function in biasing donor usage for mating-type switching. Lots of cool new data, check it out!
www.biorxiv.org/content/10.1...

Three must read papers for PhD students. #scisky #PhD #science #research #academicsky

1. The importance of stupidity in scientific research

Open Access
journals.biologists.com/jcs/article/...

Nanoscale 3D DNA tracing in non-denatured cells resolves the Cohesin-dependent loop architecture of the genome in situ - Nature Communications A nanoscale 3D DNA tracing workflow visualizes Cohesin-dependent loops in single, structurally well-preserved cells. Computer simulations based on the tracing data give further insight into how Cohesi...

Our new non-denaturing nanoscale 3D DNA tracing technology provides single-cell (and sister-chromatid specific!) readout of chromatin structure with 10kb genomic resolution - Check it out!

www.nature.com/articles/s41...

Congratulations to Kai and Oyvind!!

Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes.

🔗: doi.org/10.1016/j.ce...

#Genomics #Evolution #CellBiology #LECA

Ancient co-option of LTR retrotransposons as yeast centromeres The evolutionary origins of the genetic point centromere in the brewer's yeast Saccharomyces cerevisiae, a member of the order Saccharomycetales, are still unknown. Competing hypotheses suggest that t...

It’s out! The evolutionary origins of yeast point centromeres uncovered!

“Ancient co-option of LTR retrotransposons as yeast centromeres”

www.biorxiv.org/content/10.1...

Could blocking ‘jumping genes’ help fight disease and aging? The first clinical trials are testing inhibitors of transposons, DNA sequences that hop around the genome on their own

www.science.org/content/arti...

Lungfish xkcd.com/3064

32nd International Conference of Yeast Genetics and Molecular Biology #yeast2025 📌

#yeast #microbiology #yeastbiology #biomol

Retweets are appreciated

Masca never disappoints

Canarias recibe más de 780.000 euros para retener su talento científico Tres centros de investigación canarios se benefician de los fondos aportados por la convocatoria estatal ‘Consolidación Investigadora 2024’

Nuestras felicitaciones a nuestro investigador Jonay García Luis (@jonaygl.bsky.social), cuyo proyecto "Parasitic DNA regulation mechanisms by the Structural Maintenance of Chromosomes complex Smc5/6 (Pac-Man)" ha sido uno de los seleccionados‼️
#SomosITB

@veropaves.bsky.social

acortar.link/68Y32p

Jonay García Luis (@jonaygl.bsky.social). Investigador Ramón y Cajal, se incorpora como Investigador Responsable del grupo "Metabolismo de la cromatina (ChroMet)" a nuestro Programa en Enfermedades de base genética y raras

How does chromatin linker length affect its emergent phase behavior? 🧬👩‍🔬

We explore this question via microscopy and MD simulations: Our new paper, in collaboration with the Rosen and Redding Labs, is out today!! 🔥

A Practical Guide to Dissertation and Thesis Writing #scisky

Free Download
cambridgescholars.com/resources/pd...

I am excited to share this animation of the budding yeast inner kinetochore. Created for David Barford's lab @mrclmb.bsky.social

This DNA-binding protein complex acts as an anchor for the spindles that pull chromosomes apart during mitosis.
www.science.org/doi/10.1126/...

#blender #animation #b3d