Marco Castellani's Avatar

Marco Castellani

@holocastellani

Chromosome biology, meiotic recombination, holocentric plants ☘️❤️

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04.02.2025
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Latest posts by Marco Castellani @holocastellani

Navigating the transition to academic independence is challenging for sure. But also exciting!

03.03.2026 17:22 👍 0 🔁 0 💬 0 📌 0

I recently worked with @amarques.bsky.social to make illustrations and finalize figures for three scientific publications focusing on the evolution and function of holocentric chromosomes

I can also help you illustrate your research with effective figures, graphical abstracts, and infographics 🧪🐡

27.01.2026 11:52 👍 22 🔁 6 💬 1 📌 1
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A new extreme of meiotic evolution:

✔️ 𝗻𝗼 crossovers
✔️ 𝗻𝗼 gene conversion
✔️ 𝗻𝗼𝗿𝗺𝗮𝗹 meiosis & fertility

Sex mimics clonality without becoming asexual, in the holocentric multicellular eukaryote 𝘙𝘩𝘺𝘯𝘤𝘩𝘰𝘴𝘱𝘰𝘳𝘢 𝘵𝘦𝘯𝘶𝘪𝘴.

more about it:
www.biorxiv.org/content/10.6...

27.01.2026 10:57 👍 56 🔁 29 💬 1 📌 6
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Another beauty from our recent study!
𝐇𝐨𝐥𝐨𝐓𝐫𝐚𝐜𝐤𝐢𝐧𝐠 thousands of holocentromeres' synteny across 40 MY of evolution

Turns out holocentromeres can be stable in identity but wildly dynamic in structure. 🧬

If you want to read more about it, here: www.biorxiv.org/content/10.6...
#Centromeres #Pangenome

25.01.2026 10:28 👍 14 🔁 1 💬 0 📌 0

@amarques.bsky.social really knows how to tell a story graphically. Maybe the most information dense but visually appealing figure I've seen recently!

21.01.2026 17:54 👍 6 🔁 2 💬 1 📌 0

Pangenome analysis reveals the evolutionary dynamics of repeat-based holocentromeres https://www.biorxiv.org/content/10.64898/2026.01.17.700053v1

19.01.2026 02:32 👍 5 🔁 5 💬 0 📌 0
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📣Plant Meiosis Meeting is back for its second edition‼️
Save the date: 9–11 September 2026, Poznań, Poland🌱

More details coming soon🤩

06.12.2025 20:42 👍 18 🔁 10 💬 0 📌 1

proud to have been part of these stories! great display of our expertise, skill and insights!

21.01.2026 15:23 👍 3 🔁 1 💬 0 📌 0
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📢 Three new #bioRxiv preprints from our team on holocentric chromosomes.

Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇

21.01.2026 14:45 👍 57 🔁 36 💬 4 📌 2

2️⃣ A holocentric pangenome links karyotype evolution to meiotic recombination

🔄 Structural variation and recombination landscapes are tightly intertwined in holocentric systems.
🔗 doi.org/10.64898/202...

21.01.2026 14:45 👍 8 🔁 2 💬 1 📌 1

I recently underwent LASIK surgery to correct my myopia. I asked if i could have implants to help me with STED microscopy or deconvolution. Not an option, unfortunately.

19.01.2026 10:53 👍 0 🔁 0 💬 0 📌 0
PlantEd trainees posing across the river from the Rhine Tower in Düsseldorf

PlantEd trainees posing across the river from the Rhine Tower in Düsseldorf

PlantEd trainees on the steps in front of the mirrored pebble building in Düsseldorf

PlantEd trainees on the steps in front of the mirrored pebble building in Düsseldorf

Our 1st PlantEd Training School is underway now in Düsseldorf!

🌱🧬 With early career scientists attending from all over the world to train up on targeted plant mutagenesis, we're happy to see them out enjoying the sights yesterday evening after a packed first day!

#plantscience #earlycareer

05.08.2025 09:04 👍 3 🔁 2 💬 0 📌 0

Still digesting the EMBO Meiosis meeting. Scientific content was so high and networking too. Gathered great feedback about my project so now I'm extra motivated to carry on the good work. Until next time!
#meiosis4eva

30.06.2025 07:23 👍 1 🔁 0 💬 0 📌 0

Talks were soooo good, and it was only the first session! Can't wait for more 🤤
#embomeiosis2025

22.06.2025 18:07 👍 0 🔁 0 💬 0 📌 0

On my way to EMBO Meiosis 2025 in Engelberg!!
I'm packing some crazy results, get ready 🙏

22.06.2025 09:53 👍 3 🔁 0 💬 0 📌 0