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Marlowe Tessmer

@marlowetessmer

Executive Editor of Clinical Cancer Research, published by AACR @theaacr.bsky.social. Brown & Northwestern Alum, home chef by night. Opinions are my own. ‪@aacrjournals.bsky.social

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Latest posts by Marlowe Tessmer @marlowetessmer

Read the study, just published in Clinical Cancer Research:

Improving a Plasma Biomarker Panel for Early Detection of Pancreatic Ductal Adenocarcinoma with Aminopeptidase N (ANPEP) and Polymeric Immunoglobulin Receptor (PIGR) doi.org/10.1158/1078...

29.01.2026 19:34 👍 0 🔁 1 💬 0 📌 1
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Amplify your research impact with the power of simultaneous publication.
Learn more: buff.ly/xFawu3Z

13.02.2026 21:41 👍 1 🔁 2 💬 0 📌 0
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A synthetic cytology image generated by COIN, a controllable diffusion model designed to translate diagnostic text into anatomically & diagnostically realistic cellular imagery. This accelerates development of AI-based cytology diagnostics. Article by Zheng in this issue of Clinical Cancer Research

17.02.2026 16:35 👍 0 🔁 0 💬 0 📌 0
A Computational Pathology Model to Predict Docetaxel Benefit in Localized High-Risk and Metastatic Prostate Cancer AbstractPurpose:. Docetaxel improves survival in metastatic hormone-sensitive prostate cancer (mHSPC) and high-risk localized disease, but benefits vary substantially among patients. Without predictiv...

A Computational Pathology Model to Predict Docetaxel Benefit in Localized High-Risk and Metastatic Prostate Cancer url: aacrjournals.org/clincancerre...

Glad to see our work out now in @aacrjournals.bsky.social Clinical Cancer Research

30.12.2025 22:07 👍 2 🔁 2 💬 0 📌 0

I hope I didn't upset you in any way

04.02.2026 14:04 👍 1 🔁 0 💬 1 📌 0

done

04.02.2026 14:03 👍 1 🔁 0 💬 2 📌 0
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Sign up to receive alerts directly to your inbox to keep up with the latest published issues: buff.ly/MPqGjG9

02.02.2026 22:48 👍 2 🔁 2 💬 0 📌 0
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Not only do AACR Members receive a 10% discount on publishing fees, but some AACR scientific working groups offer additional discounts on top of this. Learn more: buff.ly/6qmKLPX

03.02.2026 15:15 👍 2 🔁 1 💬 0 📌 0

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The Impact of Concordance between Liquid and Tissue Biopsy for Actionable Mutations: Insights from the ROME Trial

Phase Ib/II Study of Zanidatamab in Combination with Tislelizumab and Chemotherapy in First-Line HER2-Positive Gastric/Gastroesophageal Junction Adenocarcinoma

04.02.2026 13:56 👍 6 🔁 1 💬 0 📌 0
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🧪Punxsutawney Phil made his sad prediction.

Only a beautiful February Cover for Clinical Cancer Research can cheer me up.

Tumor section from a patient with head & neck squamous cell carcinoma showing strong MHC-II and CD86 expressions within a proliferation center. Article by Chaudhary et al.

04.02.2026 13:17 👍 4 🔁 0 💬 1 📌 0
Systemic immune correlates of long-term survival after Delta-24-RGD based on the Therapeutic Adenovirus for Recurrent Glioblastoma Effect Trial (TARGET) Abstract. Purpose: To evaluate the combination of intra-tumoral Delta-24-RGD and subcutaneous interferon gamma (IFN-g) in patients with high grade glioma (HGG), based on the rationale that augmenting ...

🧪The authors enhanced the anti-tumor response in recurrent high grade glioma patients by combining the oncolytic adenovirus Delta-24-RGD with IFN-𝛾 to activate immune cells. Peripheral blood analysis distinguished a small number of patients with longer-term survival.
aacrjournals.org/clincancerre...

02.02.2026 00:07 👍 10 🔁 5 💬 0 📌 1
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The cover shows multiplex immunohistochemical staining of a colorectal cancer tissue section highlighting proliferating tumor cells and cytotoxic T cells within the tumor microenvironment. For details, see the article by Kastinen and colleagues in this issue of CCR.

30.01.2026 00:09 👍 18 🔁 5 💬 1 📌 0

If you are going to the AACR Annual Meeting in San Diego and want to discuss publishing your work in Clinical Cancer Research, I'll be in attendance if you want to set up a time to meet.

29.01.2026 22:53 👍 9 🔁 3 💬 0 📌 0
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What should you say to a friend who has just been diagnosed with cancer? Cancer Today asked a social worker for advice. Read her suggestions: buff.ly/nPCwAJf

29.01.2026 21:55 👍 19 🔁 12 💬 3 📌 1

A four biomarker blood panel significantly enhances the detection of early-stage pancreatic ductal adenocarcinoma.

29.01.2026 22:22 👍 10 🔁 2 💬 0 📌 1
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A study in Clinical Cancer Research reports an investigational blood panel that uses 4 biomarkers— ANPEP, PIGR, CA19-9, THBS2—to detect pancreatic cancer more accurately than the current standard test. buff.ly/wW2OR2d
@aacrjournals.bsky.social

29.01.2026 15:52 👍 11 🔁 10 💬 1 📌 1
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Look back at the AACR Journals 2025!

Clinical Cancer Research welcomed Dr. Timothy A. Yap, MBBS, PhD as Editor-in-Chief.

⏯️ Watch our interview with Dr. Yap to learn about his vision for Molecular Cancer Therapeutics and why authors should publish with the journal: buff.ly/YJXGmoW

18.12.2025 14:55 👍 1 🔁 1 💬 0 📌 0

Just a few days left to nominate someone for the CCR early career award. What are you waiting for?

29.12.2025 20:37 👍 1 🔁 0 💬 0 📌 0
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Presubmission inquiries for Clinical Cancer Research are now easier than ever:

➡️Log into the submission system: buff.ly/o6dLfLa
➡️Choose "presubmission"
➡️Provide a title, abstract, and one supporting file

16.12.2025 17:04 👍 0 🔁 1 💬 0 📌 0

📅 The January 9 submission deadline is less than a month away. Have you submitted a nomination for the Clinical Cancer Research Early Career Award?

View criteria and submit a nomination before time runs out. buff.ly/ybilkEx

19.12.2025 17:06 👍 1 🔁 1 💬 0 📌 0
FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Early Phase Trials Using Innovative Trial Designs and Biomarkers Abstract. Dosage selection for oncology drugs has traditionally relied on initial dose-finding trials to determine a maximum tolerated dose (MTD), which is then further evaluated in approval-supportin...

FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Early Phase Trials Using Innovative Trial Designs and Biomarkers url: aacrjournals.org/clincancerre...

22.10.2025 19:20 👍 0 🔁 0 💬 0 📌 0
FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Selecting Optimized Dosages for Registrational Trials Abstract. The maximum tolerated dose has historically been the recommended phase two dose, and this dosage has typically been evaluated in registrational clinical trials for oncology drugs. With the e...

FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Selecting Optimized Dosages for Registrational Trials url: aacrjournals.org/clincancerre...

22.10.2025 19:20 👍 0 🔁 0 💬 0 📌 0
FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Selecting Dosages for First-In-Human Trials Abstract. Dosage optimization has become a focus in oncology drug development, as highlighted by recent U.S. Food and Drug Administration initiatives including Project Optimus. Traditionally, most onc...

FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Selecting Dosages for First-In-Human Trials url: aacrjournals.org/clincancerre...

22.10.2025 19:19 👍 0 🔁 0 💬 0 📌 0

Check out these articles in CCR.

09.10.2025 14:58 👍 0 🔁 0 💬 0 📌 0
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Sign up to receive alerts directly to your inbox to keep up with the latest published issues: buff.ly/O6OYSDp

07.10.2025 16:07 👍 0 🔁 1 💬 0 📌 0
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Joseph C. Murray, MD, PhD, recipient of the 2025 Clinical Cancer Research Early Career Award, speaks about the questions that drive his research. To learn more, watch the full interview: buff.ly/fa085VG

03.10.2025 16:08 👍 1 🔁 1 💬 0 📌 0
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Editors’ Picks, July 2025: U.S. Cancer Mortality Hotspots, Chemotherapy-induced Hearing Loss, and More In July 2025, the AACR's journals editors highlighted studies on U.S. cancer mortality hotspots, chemotherapy-induced hearing loss, and more.

Check out Editors' Picks from the July issues, covering cancer mortality hotspots in the US, the mechanisms of chemotherapy-induced hearing loss, and how AI might help pair patients with the right therapy and predict combination therapies that can prevent cancer escape. buff.ly/yK3WqW5

30.07.2025 16:02 👍 3 🔁 2 💬 0 📌 0
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👉 Recently published in Clinical Cancer Research: A population-level real-world analysis and single-center validation of melanoma brain metastasis epidemiology following dual-agent immunotherapy 🔗 doi.org/10.1158/1078... #EANOessentials #NeuroOncology #BrainMetastases #brainMets #medsky

11.07.2025 08:18 👍 1 🔁 2 💬 0 📌 0
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If you are attending #AACRai25, meet the AACR Journals’ editors during breakfast on Friday, July 11th from 7AM – 8AM, featuring Kevin Burton, PhD, of Cancer Research, Emily Frieben, PhD, of Cancer Research Communications, and Tali Lev, PhD, of Cancer Discovery.

09.07.2025 13:08 👍 3 🔁 1 💬 0 📌 0
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Image of a metastatic lymph node from a patient with oral squamous cell carcinoma. Multiplex immunohistochemical staining highlights the spatial interplay of PERK+ macrophages, activated fibroblasts & tumor cells in an immunosuppressive niche. Article by Zhang et al. aacrjournals.org/clincancerre...

26.05.2025 17:45 👍 8 🔁 1 💬 0 📌 0