In case you missed it: our review titled "Spatial structure: shaping the ecology and evolution of microbial communities" is out! 🚨
Let me hit you with some highlights on why spatial structure matters. (and why you should care!)
Sharing is appreciated 🙏 🧵👇
doi.org/10.1093/fems...
6 bad doodles with text under each one. horseshoe crab is literally the animal horseshoe crab. shoehorse crab is a crab riding a shoe, cowboy style. crabshoe horse is a horse wearing literal crabs as shoes. shoecrab horse is a horse telling a crab to go away. crabhorse shoe is a pair of shoes, left one crab shaped, right one horse shaped. horsecrab shoe is literally the same pair of shoes, flipped.
#InvertebrateShitposting as per @joabaldwin.com's request
A pilot in a submersible vehicle collecting sediments samples in 30 meters of water looking for Asgards (microbial relatives of eukaryotes)
One of the biggest questions in biology is how complex cells evolved about 2 billion years ago. Here's my new story on how scientists are solving the mystery of eukaryotes like us. Gift link: nyti.ms/4qMbo22
![Comic. [2x2 chart. Top left quadrant: seem like dinosaurs x are dinosaurs. Silhouettes of dinosaurs stegosaurus, triceratops, tyrannosaurus, velociraptor, and long-neck dinosaur. Top right quadrant: seem like dinosaurs x are not dinosaurs. Silhouettes of mosasaur, quetzalcoatlus, dimetrodon, plesiosaur, and pteranodon. Bottom left quadrant: don’t seem like dinosaurs x are dinosaurs. Silhouettes of penguin, egret, ostrich, pigeon, falcon. Bottom right: don’t seem like dinosaurs x are not dinosaurs. Silhouettes of squirrel, stapler, plant, person, and bicycle.]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreihcxd5wcrrf5nxz3g4riglsrccbucmdns6kxrtmtj6gjgwqibp3fi@jpeg)
Comic. [2x2 chart. Top left quadrant: seem like dinosaurs x are dinosaurs. Silhouettes of dinosaurs stegosaurus, triceratops, tyrannosaurus, velociraptor, and long-neck dinosaur. Top right quadrant: seem like dinosaurs x are not dinosaurs. Silhouettes of mosasaur, quetzalcoatlus, dimetrodon, plesiosaur, and pteranodon. Bottom left quadrant: don’t seem like dinosaurs x are dinosaurs. Silhouettes of penguin, egret, ostrich, pigeon, falcon. Bottom right: don’t seem like dinosaurs x are not dinosaurs. Silhouettes of squirrel, stapler, plant, person, and bicycle.]
Dinosaurs And Non-Dinosaurs
xkcd.com/3204/
It's always important to carefully characterize the reactivity of your favorite tools to optimize applications. We teamed up with Carla Kirschbaum and Carol V. Robinson to map photolysis reaction pathways of bifunctional lipids www.biorxiv.org/content/10.6...
Methods should be used as widely as possible, so here is our detailed lipid imaging protocol, written with @martinba99.bsky.social and Chia-Yi (Christine) Chou authors.elsevier.com/a/1mU4XHRzCb... in Methods in Enzymology. Everything you need to know to do it yourself is in there -
Not everybody knows that B.B. King wrote The Thrill Is Gone during the 2nd round of revisions
How are tissue folds stabilized during animal organ development? Our latest preprint helps to answer this question, using the fruit fly wing disc as a model doi.org/10.1101/2025.... @poldresden.bsky.social @mpipks.bsky.social @dfg.de @janafuhrmann.bsky.social @vicioms.bsky.social @mbisg.bsky.social
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
In 2019, Anna Jost & @jencwaters.bsky.social reviewed best practices for validating quantitative #microscopy methods & discuss strategies to avoid unconscious bias in imaging experiments rupress.org/jcb/article/...
📕 In #Reproducibility & Best Practices in Cell Biology: rupress.org/jcb/collecti...
it was already fun to look around the documentation for cmap (cmap-docs.readthedocs.io)
but @grosoane.bsky.social just added a very cool feature to toggle between color vision deficiencies. Watch your perceptually uniform color maps gain some kinks 😂
as a mild deutan myself, I appreciate it! 🙏
If you are into imaging and quantitative biology, you should have a field day reading this. Also, of course, everyone who's into lipids ;) Huge congrats to the team!
Here's how to predict binding of tens or hundreds of small molecules to protein assemblies using Boltz 2 in ChimeraX.
Accuracy depends on how similar the ligands and binding pockets are to existing experimental structures.
www.rbvi.ucsf.edu/chimerax/dat...
Our review on contact-dependent #predation is now out ! We define predation processes and describe how predators kill and eat their prey 😈 Repost appreciated ❤️
The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Joachim Goedhart to the left, text to the right 100 extraordinary biologists Joachim Goedhart As one of the most prolific authors on the Node, Joachim Goedhartwrote the Node’s most-read post 'Data Visualization with Flying Colors'. He is an Assistant Professor at the University of Amsterdam, the Netherlands, unravelling G-protein signalling networks in time and space in cells and tissues. #100biologists #biologists100
This week, we are featuring Joachim Goedhart, one of the most prolific authors on @the-node.bsky.social, as an extraordinary biologist. #100biologists
@joachimgoedhart.bsky.social
I gave in! After students asking for it, I now made a simple figure design checklist.
To help all scientists w/o graphic skills create clear, accessible, and truthful charts!
-> Out in @nature Cell Biology: rdcu.be/erwl4
#DataVisualization #PhD #SciComm
Thx for review @bethcimini.bsky.social + 2
Yep, we sure do! A fine thought technology from Katherine Andrea Rivera-Gomez and Mara Schvarzstein:
wbg.wormbook.org/2017/07/18/i...
Das Foto zeigt Walter Lübcke, den von einem Neonazi ermordeten Regierungspräsidenten von Kassel, in einem schwarz-weißen Foto mit einem schwarzen Anzug und einem weißen Hemd.
#KeinVergessen
Weil er öffentlich für Menschrechte von Geflüchteten einstand, wurde Walter Lübcke heute vor 6 Jahren von einem Neonazi ermordet. Der Mörder des CDU-Regierungspräsidenten von Kassel war u.a. bei #AfD aktiv und fasste den Tatplan nach AfD- und Neonazi-Mobilisierungen in #Chemnitz 2018.
E11 Bio is launching Volara: an open-source Python library for block-wise processing of large volumetric microscopy datasets! 🧪🔬
Volara features block-wise task abstractions, making scalable image processing more accessible, robust, and repeatable.
Read more: e11.bio/blog/volara
Meet GEQO: Genetically-encoded biosensors for absolute small-molecule quantification in single cells brought to you by @sascha-kuhn.bsky.social. For simple absolute quantification of your favourite small molecule or ion, head on over to @bioarxiv and read our new preprint: doi.org/10.1101/2025...
How can organs regenerate fast? Bioelectricity helps -- by coupling sub-second electrical injury signals to regenerative proliferation.
First preprint from my potsdoc :D with @liujinghui.bsky.social @ritamateus.bsky.social @mpi-cbg.de and collaborators @mpipks.bsky.social @csbdresden.bsky.social
It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that.
www.biorxiv.org/content/10.1...
My lab has a tradition that each week one person contributes edits to a Wikipedia page relevant to their scientific work, and then presents it briefly at lab meeting (and we clap). A few of my favorites:
en.wikipedia.org/wiki/Proprio...
en.wikipedia.org/wiki/Chionea
en.wikipedia.org/wiki/Femoral...
Line of zebrabow embryos that have different colors based on the cell lineage. They are sorted by color to form a rainbow.
Full spectrum of ‘zebrabow’ embryos. Credit to @jhenninger.bsky.social. #ZebrafishZunday 🧪
I love seeing so many interesting papers on Bluesky and my reading list keeps growing. So I would like to share a thread about our paper from this year. It was published when we were still at *the other place*, and I didn't feel like writing about it there.
www.science.org/doi/full/10....
1/n
This cover came out when I was 14 but I never heard it.
It's hard to explain but I somehow I feel like it would have changed the course of my life if I had.
We are happy to report that our journals and community sites now have Bluesky accounts. Follow them at:
@dev-journal.bsky.social
@jcellsci.bsky.social
@jexpbiol.bsky.social
@dmmjournal.bsky.social
@biologyopen.bsky.social
@the-node.bsky.social
@prelights.bsky.social
@focalplane.bsky.social
And what better introduction than to share a new publication? Check out this review article I’ve been working on (along with my co-first authors) if you need a biosensor or want a comprehensive overview of the field. Now out as an ASAP article at Chemical Reviews! doi.org/10.1021/acs....
