Resia Pretorius

Scientists reveal another piece in Long COVID puzzle In patients with Long COVID, a new study has revealed structural association between circulating microclots and neutrophil extracellular traps (NETs). This finding suggests the existence of under...

#Apresj20 #LongCovid #Science #Research #Coagulation #Inflammation
@resiapretorius.bsky.social

🔗 Communiqué de Presse :

Where spike is involved LongCOVID will be a significant possibility for vulnerable individuals
. Symptoms from newer variants might be less severe in acute stage, but LongCOVID is know not to reflect acute severity.

I have asked my @WHN collaborators their thoughts. This is an interesting indeed!

Exercise-induced Changes in Microclotting and Cytokine Levels Point to Vascular Injury and Inflammation in People with Long COVID www.researchsquare.com/article/rs-6... @profmarkfaghy.bsky.social @dbkell.bsky.social @resiapretorius.bsky.social

Amyloid Presence in Acute Ischemic Stroke Thrombi: Observational Evidence for Fibrinolytic Resistance | Stroke

🧠 Daily Feed of Brain Damage 🧠

Part 2

Sincerest thanks to @resiapretorius.bsky.social and @dbkell.bsky.social

www.ahajournals.org/doi/10.1161/...

1/ Fantastic new preprint from
@resiapretorius.bsky.social @CallumThomas96 @DrMark_Faghy and co. This new study suggests that even light exercise may worsen #LongCOVID. by breaking up #microclots and triggering inflammation.

researchsquare.com/article/rs-6...

Here’s what they found:

Another new preprint with
@resiapretorius.bsky.social
is available, on a technique called #Nailfold #Capillaroscopy that we think will be an important complement to #microclot measurements. preprints.org/manuscript/2... #TeamClots

One year ago this excellent paper was published
Myalgic Encephalomyelitis/
Chronic Fatigue Syndrome: the
biology of a neglected disease
Hayley E. Arron, Benjamin D. Marsh,
Douglas B. Kell, M. Asad Khan and Etheresia Pretorius www.frontiersin.org/journals/imm... #ME/CFS @resiapretorius.bsky.social

These findings suggest that PV/PIS is characterized by persistent immune dysregulation and coagulopathy, with proteomic signatures only partially overlapping those previously reported in prior proteomics analysis on Long COVID samples collected prior to vaccination availability. Our results highlight the complex interplay between immune activation, endothelial dysfunction, and coagulation pathologies in PV/PIS, while also highlighting distinct differences between these systems in Long COVID and PV/PIS, paving the way for more targeted protein research in these conditions.

www.researchsquare.c...

Ein sehr interessanter Preprint vom Team um @resiapretorius.bsky.social und @dbkell.bsky.social, der ein neues Licht auf die hier „PV/PIS“ genannte Entität wirft, an der bisher ja oft Weltanschauungen aneinandergeprallt sind.
1/2

Pleased that the paper on #TCM and #Microclots and blood stasis with
@resiapretorius.bsky.social
preprinted at preprints.org/manuscript/2... has just been accepted for full publication. #TeamClots

LONG COVID IN CHILDREN MEETING IN ROME - INCLUDING LONGCOVID KIDS UK TALK FROM SAMMIE YouTube video by BUONSENSO & THE KIDS_

Our thanks to all the authors.
@laelyonker.bsky.social
@buonsenso.bsky.social
@binitakane.bsky.social
@resiapretorius.bsky.social
@sammiemc.bsky.social
@petterbrodin.bsky.social
and all the team.

Watch the authors presentations from Rome Nov 2024 here.
www.youtube.com/watch?v=lhbp...

🧪 #LongCovid #MECFS
Suscribe to
YouTube Channel
@Unite2Fight2024
youtube.com/@unitetofigh...
>40 world experts explain
the state of research on Long Covid & ME
May 2024
@sunny-rae1.bsky.social
@resiapretorius.bsky.social
@putrinolab.bsky.social
@virusesimmunity.bsky.social
@vpuntmann.bsky.social

A message from Resia Pretorius on Long COVID Awareness Day 2025 YouTube video by NeurologistMom

“I know your journey feels overwhelming, and the questions about the future can be heavy, but I want to tell you this; research is progressing...”

Resia Pretorius @resiapretorius.bsky.social has a message for us #LC2025hopevideos #longcovidawarenessday2025

youtu.be/g5bWuGTeqyE

UniteToFight We envision a world free of Long Covid & ME/CFS stigmatization, where every individual can thrive. Our mission is to create an inclusive, interactive space to address unmet needs and drive societal ch...

⬆️ @dbkell.bsky.social
&
@sunny-rae1.bsky.social
@resiapretorius.bsky.social

@Unite2Fight2024
youtube.com/@unitetofigh...

Talks from >40 world experts explaining the state of research on #LongCovid & #MECFS
@putrinolab.bsky.social
youtu.be/dOg_WCIOqkE?...
Dr Martin Kräter
youtu.be/Eds4MQk9ba0?...

I am excited to share that our imaging flow cytometry microclot analysis is now done in Europe! The Swiss lab INUS Laboratories AG has the licence!

inus.health/en/lab/

How Long COVID Research Could Change the Way We Think About Blood Microclots Knowledge of the condition’s microclots could make a macro difference.

How Long COVID Research Could Change the Way We Think About Blood Microclots Knowledge of the condition’s microclots could make a macro difference.

Thank you @thewhn.bsky.social, for giving me the best mentors in #LongCovid research!
@resiapretorius.bsky.social is one of them, and everyone should follow her pioneer work in LC and blood clots! Thank you for the microscopy tips!♥️🔬

More about her work: shorturl.at/Ic9NT

2/ This year I'm a patient representative for #nihRECOVER. Hoping I can push for or contribute to studies around #LongCovid impact on immune system & cancer. h/t @bhanlon15.bsky.social @virusesimmunity.bsky.social @resiapretorius.bsky.social @ahandvanish.bsky.social

The recording of the 1st meeting on #LongCovidKids is available online! youtube.com/watch?v=V6ll...
Check the talks of leaders in the field
@putrinolab.bsky.social, @resiapretorius.bsky.social, @binitakane.bsky.social, @petterbrodin.bsky.social, and others. Thank you, @buonsenso.bsky.social 🙌

Treatment of Long COVID With Enoxaparin : Cardiopulmonary Physical Therapy Journal symptoms, via reduced blood flow and cellular energy production. Postexertional malaise (PEM) is common and exercise therapy should not be recommended without addressing the underlying pathology. Cas...

Happy to share a case study with lead Ciara Wright and @putrinolab.bsky.social and @dbkell.bsky.social
An example of LongCOVID treatment.

journals.lww.com/cptj/fulltex...

I collaborate widely with my Long C-19 WHN Group who are everywhere. @putrinolab.bsky.social in NYC
@resiapretorius.bsky.social in South Africa
@andrewewing11.bsky.social Sweden... Tip of my iceberg.

I'm in Sydney.
👍🏻

Cardiovascular and haematological pathology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): A role for viruses ME/CFS is a debilitating chronic condition that often develops after viral or bacterial infection. Insight from the study of Long COVID/Post Acute Sequelae of COVID-19 (PASC), the post-viral syndrome ...

Cardiovascular and hematological pathology in #MECFS: A role for viruses pmc.ncbi.nlm.nih.gov/articles/PMC... @resiapretorius.bsky.social et al. (2023)

Love Actually: Long Covid Version YouTube video by SeekingBostonMarathon

A Seeking Boston holiday classic, "Long Covid Actually" with @putrinolab.bsky.social @resiapretorius.bsky.social @dbkell.bsky.social mentions. #LongCovid youtu.be/JlJ2YXpIrYM?...

Prof. Dr. Resia Pretorius: Microclots and Platelet Hyperactivation in Long COVID (Day 1, Block 2) YouTube video by UniteToFight

#UniteToFight2024

Prof. Dr. Resia Pretorius' talk on 'Microclots and platelet hyperactivation in #LongCovid' is now available with 🇪🇸 subtitles: youtu.be/L1LiwMW0mCg
@resiapretorius.bsky.social

You can use YouTube's auto-translation for subtitles in many other languages.

The #UniteToFight2024 talk by @resiapretorius.bsky.social on microclots and platelet hyperactivation is now also available with Spanish subtitles.

Huge thanks to @onaalbizu.bsky.social for the translation!

Stacking the Deck - The systemic review recommending CBT & exercise for Long Covid. On Thursday 28th November a new paper was released in The BMJ, recommending CBT and exercise for Long Covid...

🃏Uncover the stacked deck of the new meta-review recommending CBT & Exercise for Long Covid.

Dive deep into the biased evidence and flawed conclusions in this eye-opening analysis.

🔊Audio available
www.longcovidadvoc.com/post/stackin...

3/3)

“… we shall look away from, and not see, whatever might be dangerous to our pet theories….”

That BMJ review of Long Covid therapies does not show what it says it does The BMJ have published a “living systematic review” of interventions for the management of Long Covid. It sets out to gather all relevant studies, and to comb their findings in order to see what works...

2/3) Here is an assessment by Brian Hughes, who states “Something seems very off about how it’s all done”. He discusses the critically flawed methods used by the authors:

thesciencebit.net/2024/11/28/t...

Interventions for the management of long covid (post-covid condition): living systematic review Objective To compare the effectiveness of interventions for the management of long covid (post-covid condition). Design Living systematic review. Data sources Medline, Embase, CINAHL, PsycInfo, Alli...

1/3) I am sure many are aware of this review in the BMJ:

www.bmj.com/content/387/...

2/2) “They are releasing draft recommendations every month, with a brief period for public feedback. We have significant concerns with their draft recommendations for November 2024, and we encourage as many people as possible to submit comment”

Say no to harmful Long COVID recommendations Respond risky recommendations to use exercise to prevent Long COVID, cognitive behavioural therapy (CBT) to treat it, and more. Deadline November 27, 2024.

1/2) Please comment, link below: Please comment see link below: “Cochrane Canada and the McMaster GRADE Centre at McMaster University, are in the process of developing guidelines to prevent and treat Long COVID in Canada”

donoharmbc.ca/can-pcc-nov2...

Increased Levels of Inflammatory and Endothelial Biomarkers in Blood of Long COVID Patients Point to Thrombotic Endothelialitis - PubMed The prevailing hypotheses for the persistent symptoms of Long COVID have been narrowed down to immune dysregulation and autoantibodies, widespread organ damage, viral persistence, and fibrinaloid micr...

Because you have been looking at the original preprint. Here is the published paper’s link: pubmed.ncbi.nlm.nih.gov/37207671/