Love you Thorsten!
20.02.2026 16:27
π 3
π 0
π¬ 0
π 0
Love you Thorsten!
In September 2024, I was diagnosed with ALS. Today, I can no longer speak, I am confined to a wheelchair, and I can no longer move my arms. It's really shitty. I will write here soon about how I am coping with this and how I am trying to stay cheerful. #ALS
We;re hiring Junior Group Leaders! π¬β¨
Weβre looking for researchers in immunology, chemical biology, AI in biology, or protein design to launch their own independent groups in our collaborative, international environment.
www.nki.nl/news-events/...
Very nice work, congrats!
Very happy that NWO supports this major upgrade of our national EM infrastructure. It is great that this initiative got broad support all over NL, and it will EMPower fantastic science - looking forward to that!
www.uu.nl/en/news/33-m...
Are you excited to uncover the molecular mechanisms of actin filament assemblies that drive cell migration using cryo-EM?
Only 1.5 week to apply for this exciting PhD position in my newly established lab at the Netherlands Cancer Institute in Amsterdam: www.werkenbijavl.nl/vacatures/ph...
Thank you π
Thank you, hope all is well in Berlin! π
Although I was 6 years old at the time - your papers were still very useful for this new work π
Thank you for appreciating our work!
Thanks Lennart π
This is a perfect farewell to the @mpi-dortmund.bsky.social and the @raunser-lab.bsky.social. Big thanks to the whole team π.
Interested in doing equally exciting work? I have open positions available soon in my newly established lab at the @nkinl.bsky.social in Amsterdam.
Very excited that my final postdoctoral work is now online in Cell @cellpress.bsky.social.
www.sciencedirect.com/science/arti...
Using 16 (!) cryo-EM structures, we uncovered how the three proteins coronin, cofilin and AIP1 work together to rapidly disassemble actin filaments.
Choreography of rapid actin filament disassembly by coronin, cofilin, and AIP1 pubmed.ncbi.nlm.nih.gov/41075793/ #cryoEM
We just published this paper of which I am immensely proud: www.nature.com/articles/s41...
In the study, we uncover how the enzyme MPO disassembles #nucleosomes in a process called NETosis, a funky mechanism of #neutrophils to kill #pathogens that you might have never heard of.
Let's dive in... π§΅
My final postdoctoral work will come out very soon, so watch this space π§.
In Amsterdam, I aim to decipher the molecular mechanisms of (cancer)-cell migration and adhesion using structural biology approaches. Positions available soon, so please reach out when you are interested! π
This marks the end of >4.5 years as a postdoctoral researcher at the @mpi-dortmund.bsky.social. Massive thanks to my advisor @raunser-lab.bsky.social for the invaluable guidance and support; and the entire department for making it an unforgettable experience!
2/3
Thrilled to announce that from tomorrow (October 1st), I'll start as a junior group leader at the Netherlands Cancer Institute (NKI) @nkinl.bsky.social in Amsterdam π.
www.nki.nl/news-events/...
1/3
Featuring #AlphaBridge features from @alvarezsalmoral.bsky.social, with @jonasteuwen.bsky.social and team, our new work from @nkinl.bsky.social nl.bsky.social @oncodeinstitute.bsky.social . Have a look at ahmpc.eu for more!
Nature research paper: Molecular mechanism of ultrafast transport by plasma membrane Ca2+-ATPases
go.nature.com/3HpdTqq
The video takes more than half a minute for illustrative purposes. However, these PMCA2-NPTN complexes can in reality pump calcium out of the cell at a speed of 5,000 (! π€―) ions per second.
Happy to have made a tiny contribution to this work (including the shown movie π). Amazing work by Fakler lab @uni-freiburg.de and @raunser-lab.bsky.social @mpi-dortmund.bsky.social about Ca-ion transport by PMCA2-NPTN complexes, now out in @nature.com
www.nature.com/articles/s41...
Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that werenβt apparent before.
www.biorxiv.org/content/10.1...
Great story, congratulations!
Some happy news. Pleased to see our paper showing how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex out in Science Advances: bit.ly/3EFpD6h
Cool story, congrats!!
Working on actin cytoskeleton and Arp2/3 complex? Check out our latest workο½https://www.biorxiv.org/content/10.1101/2025.01.31.635869v1
In this work, we found SPIN90 forms a dimer, facilitating bidirectional actin filament nucleation by activating two Arp2/3 complex #Cryo-EM #Actin #Arp2/3
Thank you π!
Danke schΓΆn mein Sohn. Hope everything is well in Boston.
My first post on this forum! π
I am happy to share that our #openaccess review on the #molecular mechanisms of #actin filament polymerization and dissasembly is now online @cp-trendscellbio.bsky.social
www.cell.com/trends/cell-...
Big thanks to my amazing colleagues in Dortmund
