Prasad Jallepalli, MD, PhD

Your Honor, we've crimed so much that it's impossible for us to pay for our crimes

Exactly right.

The Civil Rights Division was able to show that it took exhaustive (and exhausting) work to litigate even the most obvious violations of the voting rights protections in the 1957 and 1960 acts, which ultimately convinced Congress and then SCOTUS that a much broader law was needed.

The Bygone Era of Supreme Court Support for Voting Rights Sixty years after upholding the Voting Rights Act, the Court has dismantled most of it.

Tomorrow marks the 61st anniversary of Bloody Sunday in Selma, Alabama. It also marks the 60th anniversary of the Supreme Court first upholding the Voting Rights Act.

We have gotten so, so far away from a Court that cares about democracy.

New from me at @brennancenter.org:

neocons know the neocon

The Trump administration took your money illegally.

They won’t give it back.

A proteome-wide dependency map of protein interaction motifs - Nature Structural & Molecular Biology Ambjørn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicte...

Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. www.nature.com/articles/s41...

The memory of the righteous is a blessing

And the over $1 trillion dollar cut to Medicaid will absolutely undermine even this relatively good labor market.

12/“I spent five hours creating a justification for why the word the screening tool picked up was a false positive - I was told my judgment was wrong. When I asked to document that my decision was overruled I was told that the decision memo could not include “dissenting language.”
- anonymous NIH PO

This middle part of the thread points to specific examples of potential/ongoing automation of ideology-driven evaluation, i.e., using tools to screen for alignment with administration priorities. There are significant implications here for oversight of what is unfolding with NIH grants & reviews.

Current NIH leadership want you to think they are using rigorous, consistent & scientific processes to screen studies to align them with agency priorities.

But the process that they have put down on paper is a sham.

It’s important to know NIH is not following its own guidance. Here’s why:

🧵1/

An advance look at the cover for next week’s issue: “War-a-Lago,” by Barry Blitt. #NewYorkerCovers

Dow drops 900 after oil prices jump to highest in nearly 2 years and data show a slowing US economy U.S. stocks are falling sharply after getting a whiff of a worst-case scenario for financial markets: a weakening economy combined with high inflation.

U.S. stocks are falling sharply Friday after getting a whiff of a worst-case scenario for financial markets: a weakening economy combined with high inflation.

Chicagoans, joined by 3 former presidents, gathered to say goodbye to the Rev. Jesse Jackson.

The People’s Celebration is expected to be the largest gathering to honor Jackson’s life, as it’s being held in a church with seating for 10,000. blockclubchi.co/3OSSdpZ

Like with ICE arresting restaurant workers after eating there, the Trump admin keeps committing sins that would have had you punished by the gods going back into prehistory

exercise, while not *criminal*, is fucking abominable. There's an unspoken expectation of safe-conduct while transiting to and from such exercises which is why it could be unarmed in the first place. Attacking such a ship is morally no different from violating a guest right. Deeply dishonorable

During the Gingrich shutdown I repeatedly broke into a closed Federal facility, often hiding from guards in the dark, so I could finish my research before my post-doc ended.

It feels like we're getting to a place even worse than what the Black Mirror folks used to conjure up.

not to mention we’re now are committed to *post-war nation building*

speed running the entire Iraq war inside a week

setting everyone’s money on fire (except for what he skims off the top)

the time horizon to that default wave could be very long — and the longer it is, the harder it becomes to reconstruct anything

rebuilding after WWII was the exception not the rule

Data visualization is a critical step in data analysis. 8 links to bookmark for better data visualization:🧵

As I get older I’m coming to increasingly radical views like “eradicating peoples jobs is bad, actually” and “a necessary part of having skills is taking responsibility for the outcomes of those skills”

As I get older I'm coming to increasingly radical views like "you have to do things to get good at them" and "you have to think about problems to solve them"

CNN's Dana Bash reports on a conversation she just had with Trump: "He quickly turned to Cuba. He said without being asked, 'Cuba is going to fall pretty soon.'"

How the FDA is choosing to regulate companies right now

"Unconditional surrender."

This sounds like a war to me despite Hegseth, Rubio, and Republicans saying it's not a war.

Govt asks 1st Circuit for emergency stay to maintain DHS's policy of removing noncitizens to 3d countries with minimal process. Judge Murphy declared it illegal. If stay is denied, govt will go straight to SCOTUS, which twice stayed Murphy's preliminary injunctions.

The people — and research — lost in the NIH exodus | CNN Former National Institutes of Health employees reveal how the Trump administration played a role in their decisions to leave the agency. Under Trump, workers claim the NIH became a “hostile work envir...

“To see us going backwards,” [Dr Chou] added, “it just made me feel like I have limited time on this earth and I cannot participate anymore inside the system.”

www.cnn.com/2026/03/05/h...

Six federal scientists run out by Trump talk about the work left undone | CNN Federal data shows the NIH lost about 4,400 people — more than 20% of its workforce. Scientists say the departures harm the U.S.’ ability to respond to disease outbreaks, develop treatments for chroni...

"Many scientists, however, question whether the NIH can still fulfill its public mission."

www.cnn.com/2026/03/05/h...