Valentín Iglesias

Liquid-liquid phase separation (LLPS) as a sensing and adaptation mechanism: An evidence-based hypothesis on AP2 transcription factors in the malaria parasite https://www.biorxiv.org/content/10.64898/2025.12.10.693351v1

Happy to see the project highlighted on the main webpage of my university!

www.umb.edu.pl/aktualnosci/...

A huge thanks to
@burdukiewicz and @_jarochi for all the help, and to Mariola Maciejak from the @UMB_Bialystok
project acquisition team as well!

Thrilled to share that I have received funding from
@ncn.gov.pl
🎉 to study the interaction between microbial proteins and Aβ42 and α-synuclein. Very excited to get started! #Miniatura9

PUBMED is down. This is disaster !!
We do not have the system and organization to replace it. (EuroPMC is great but not a replacement)
It is crystal clear that we cannot depend on critical systems provided by a single provider.
European reaction has to include science and science infrastructures.

First of four screen grabs showing “Safari can’t open the page because the server can’t be found” error messages on NIH, NCBI, GenBank and BLAST websites.

Second of four screen grabs showing “Safari can’t open the page because the server can’t be found” error messages on NIH, NCBI, GenBank and BLAST websites.

Third of four screen grabs showing “Safari can’t open the page because the server can’t be found” error messages on NIH, NCBI, GenBank and BLAST websites.

Fourth of four screen grabs showing “Safari can’t open the page because the server can’t be found” error messages on NIH, NCBI, GenBank and BLAST websites.

The NIH website, including NCBI, GenBank, and BLAST are down. I thought it might be a brief outage so waited 12 hours and checked again before posting this. They’re still down.

It is hard to express just how fundamental these tools are to biology and medicine: research, applied, public and private.

Summary of active amyloid databases.

Curious about the scope of data resources available on #amyloid aggregation? Our review provides a comprehensive overview (doi.org/10.1016/j.cs...), and all details are on our dedicated site: biogenies.info/amyloid-data.... Check it out to explore the landscape of amyloid data! 1/3

Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease - Nature Neuroscience Yuan et al. find that the kidney can serve as a site of initiation for the spread of pathological α-synuclein to the brain, contributing to the development of Parkinson’s disease (PD) and providing a ...

Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease 🧠🧪

www.nature.com/articles/s41...