You are finishing your PhD and looking to continue in science?
The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....
Thanks for reposting!
Macro photograph of an abalone shell
Owlish Eyes
#424 taken 4:25 pm
#art #nature #photography #abstract
🧪🔬 Der Gemeinsame Ausschuss zum Umgang mit sicherheitsrelevanter Forschung von @dfg.de und Leopoldina 🤝 hat seine 2020 erstmals veröffentlichten Leitfragen zur ethischen Bewertung sicherheitsrelevanter Forschung aktualisiert: www.sicherheitsrelevante-forschung.org/publikation-...
Passionate about transcription?
🚀 We’re recruiting a PhD student in Transcriptional Regulation at @ucph.bsky.social Start Summer 2026
Work with RNA, CRISPR, sequencing & proteomics in the Gregersen Lab @cgen2025.bsky.social
Meet us: gregersenlab.com
Apply by Apr 10, 2026👇
tinyurl.com/PhD-CGEN
If you want to explore ncRNA dynamics during mammalian development, love microscopy, and are not afaraid of transposons biology, apply‼️
We are looking for a postdoc to join our team at @imbavienna.bsky.social
More details 👇🏻
you think you've seen the whole movie, and then the alt text reveals you haven't even finished act two
Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the thread👇 for the highlights of our findings.
Oh no, this shouldn't exist
So excited to share this manuscript led by the inimitable Cara Brand, who discovered that Topoisomerase II evolution causes hybrid female lethality in Drosophila.
Congrats to Cara, @nickbr0wn.bsky.social, Anirban, and
@buszczaklab.bsky.social!
www.biorxiv.org/content/10.6...
Our paper is now out in Nature:
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.nature.com/articles/s41...
A short thread on how retrotransposons helped give rise to yeast point centromeres.
1/14
This duet cover of Radiohead's "Creep", between a son and his Shastriya Sangeet classically trained mother, is the mash-up I didn't know how much I needed in my life. Totally spontaneous sobbing may have taken place.
www.youtube.com/watch?v=nZoH...
Turner et al. investigated the role of chromosomal rearrangements during habitat shifts in two locally adapted populations of Drosophila from the island of São Tomè; findings suggest that rearrangements may act as a source of innovation.
🔗 doi.org/10.1093/gbe/evaf236
#genome #evolution #drosophila
I'm very excited to share our newest preprint, where we show that long, linear bifunctional molecules like PROTACs can bind within the narrow ubiquinone-binding tunnel of mitochondrial complex I, leading to off-target mitotoxicity.
www.biorxiv.org/cgi/content/...
(1/4)
The demystification of piRNA clusters
if you wonder how cells generate piRNAs specifically against transposons & you are looking for a weekend read
check out @86dominik.bsky.social's opus magna (or Dominik's great thread)
a shared project with the one and only Rippei Hayashi, lab alumnus & friend
Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine.
faculty-einstein.icims.com/jobs/17847/a...
Sir Ian McKellen performing a monologue from Shakespeare’s Sir Thomas More on the Stephen Colbert show. Never have I heard this monologue performed with such a keen sense of prescience. Nor have I ever been in this exact historical moment.TY Sir Ian, for reaching us once again.
#Pinks #ProudBlue
Terrific paper on a new chromosomal
compartment where extensive loop
extrusion isolates domains from
other such domains
H3K79me2/3 is sufficient to antagonise PRC1 www.nature.com/articles/s41...
Ad for a postdoc position in centromere biology with colorful chromosomes and centromeres made out of FIMO.
🧪 My lab has an opening for a postdoc position soon! Please share/get in touch!
Congratulation and I hope you get accepted by JAXA soon 🚀
Congratulations!
Time for a thread on our Christmas preprint “Origin and evolution of acrocentric chromosomes in human and great apes”. I had so much fun with this project and paper. It will be hard to summarize in a thread, but I’ll try www.biorxiv.org/content/10.6... [1/21]
Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element www.biorxiv.org/content/10.6...
1⃣9⃣ anys de compromís de Maruxa Martínez amb el PRBB.
💪 Pionera en la presència del parc a les xarxes socials, arquitecta digital d'El·lipse i defensora de la integritat i la inclusió.
Repassem el seu llegat 👇
![3-panel comic. (1) [Three small arthropods on ocean floor.] ARTHROPOD 1: Now that we’re multicellular, what are your plans? I’m gonna evolve little legs and swim around with them! ARTHROPOD 2: I’m gonna evolve sharp pincers and use them to crunch stuff! ARTHROPOD 3: I’m gonna evolve glands to make string from my butt and use it to construct elaborate geometric nets hundreds of times my size to catch other animals. (2) [Silence] (3) ARTHROPOD 1: *Dude.* ARTHROPOD 2: Can you *please* just be normal about this? ARTHROPOD 3: *What??!*](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreia3p425asp237hjolbn5lly6g6hzm2eoygqjpkd5dii6zrwqnp7qi@jpeg)
3-panel comic. (1) [Three small arthropods on ocean floor.] ARTHROPOD 1: Now that we’re multicellular, what are your plans? I’m gonna evolve little legs and swim around with them! ARTHROPOD 2: I’m gonna evolve sharp pincers and use them to crunch stuff! ARTHROPOD 3: I’m gonna evolve glands to make string from my butt and use it to construct elaborate geometric nets hundreds of times my size to catch other animals. (2) [Silence] (3) ARTHROPOD 1: *Dude.* ARTHROPOD 2: Can you *please* just be normal about this? ARTHROPOD 3: *What??!*
Early Arthropods
xkcd.com/3199/
Beautiful!
📢 Three new #bioRxiv preprints from our team on holocentric chromosomes.
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
We are thrilled to share our new pre-print: “System-wide extraction of cis-regulatory rules from sequence-to-function models in human neural development”. S2F-deeplearning models can accurately encode enhancers, yet decoding these models into human-interpretable rules remains a major challenge.
Our Mini Review went online last night in Current Opinion in Genetics & Development
"Block copolymer concepts of how transcription organizes the stem cell genome"
doi.org/10.1016/j.gd...
Fig. 1: Stem cell–typical organization of the genome and transcription, and the block copolymer sorting concept.
