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Nat Clarke

@natclarke

Assistant Prof @univmiami.bsky.social. Cellular and Developmental Biology / Evo-Devo / Animal Multicellularity / Cell adhesion. Lover of weird invertebrates. Learn more: clarkelab.com

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26.08.2023
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Latest posts by Nat Clarke @natclarke

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๐Ÿšจ3-year Postdoc Position @halloulab.bsky.social (Kennedy Institute, Oxford) - on Spatial Biology & Bioinformatics of Fibrosis๐Ÿšจ

An exciting project combining #SpatialTranscriptomics & #Mechanobiology๐Ÿ‘‡:

shorturl.at/LLS5r

Deadline: 16 March - Please RT ๐Ÿ“ข!

@kiroxford.bsky.social @ox.ac.uk

02.03.2026 07:58 ๐Ÿ‘ 23 ๐Ÿ” 18 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Glob-glob! Absolutely magical sea anemone larva (about 7 mm) from The Lombok Strait, Indonesia ๐Ÿ‡ฎ๐Ÿ‡ฉ

01.03.2026 13:11 ๐Ÿ‘ 1027 ๐Ÿ” 299 ๐Ÿ’ฌ 14 ๐Ÿ“Œ 21

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief ๐Ÿงต (carried over from the old place)

28.02.2026 08:12 ๐Ÿ‘ 339 ๐Ÿ” 137 ๐Ÿ’ฌ 16 ๐Ÿ“Œ 16
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Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate - Nature The choanoflagellate Choanoeca flexa forms motile and contractile cell monolayers purely clonally, purely aggregatively or through a combination of both processes depending on environmental condi...

Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate www.nature.com/articles/s41... #jcampubs

25.02.2026 17:06 ๐Ÿ‘ 51 ๐Ÿ” 23 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
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Introducing a Clytia planula cell atlas, and demonstrating broad-level relations with medusa cells via another updated atlas. By @annaferraioli.bsky.social with @juliarmateu.bsky.social and collaborators in a project led by @rcply.bsky.social @biodev-vlfr.bsky.social www.biorxiv.org/content/10.6...

18.02.2026 06:59 ๐Ÿ‘ 35 ๐Ÿ” 14 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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New preprint @biorxiv-devbio.bsky.social by Harshath Amal and colleagues from our lab @uni-muenster.de shows how a BMP #morphogen gradient is translated into graded junctional permeability by tuning adhesion and actomyosin contractility in #Drosophila
See tinyurl.com/yhbwd9xh
@sfb1348.bsky.social

18.02.2026 08:43 ๐Ÿ‘ 80 ๐Ÿ” 29 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 1

Cool new preprint from @jacobmusser.bsky.social and @cellulo-evo.bsky.social on monoamine signaling in sponges! ๐Ÿงฝ

18.02.2026 16:01 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Huge congrats, Roy! Glad to see this out, and Iโ€™m excited to dig into it

18.02.2026 15:59 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

This is awesome! Beautiful data! Looking forward to reading it

17.02.2026 17:00 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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A ๐Ÿ†• #Ichthyosporea story
Led by@margaridaaraujo.bsky.social, in Co. @gautamdey.bsky.social & @hiralshah.bsky.social+๐Ÿ”ฅteam across @embl.org & @sciencesunige.bsky.social
We finally have a look at what #microtubules are doing during #cellularization in #Sphaeroforma
โ–ถ๏ธ tinyurl.com/MTSARC
#ProtistsOnSky

17.02.2026 13:02 ๐Ÿ‘ 89 ๐Ÿ” 41 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 4
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Two funded PhD positions investigating the evolution of sarcomeres @ibdm.bsky.social in @biancah0406.bsky.social and our lab, together with @cnidevo.bsky.social - Interested to explore how similar or different Jellyfish sarcomeres are to Drosophila or human ones?
www.ibdm.univ-amu.fr/ibdm_job/2-a...

16.02.2026 10:49 ๐Ÿ‘ 45 ๐Ÿ” 35 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller?

Excited to share our latest work in @science.org on a new small polymerase.
1/n

13.02.2026 11:42 ๐Ÿ‘ 497 ๐Ÿ” 209 ๐Ÿ’ฌ 10 ๐Ÿ“Œ 28

Postdoc position available!!! We are looking for a creative postdoc to develop independent research directions in tissue morphogenesis using embryos, stem cell/organoid systems, and quantitative imaging and/or biophysics. Here are the details: livejohnshopkins-my.sharepoint.com/:b:/g/person...

06.02.2026 17:05 ๐Ÿ‘ 6 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Iโ€™m recruiting new members to the Farrell Lab this summer. We will have space for 1 postdoc (since Abhinav is leaving to start his own lab at U Arizona!!) and 2 postbacs, since my current two will leave for PhD programs at the end of the summer. More details in thread:

29.01.2026 17:43 ๐Ÿ‘ 28 ๐Ÿ” 24 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 5

Another way to speak up - call your senators: www.callyoursenate.com

26.01.2026 14:32 ๐Ÿ‘ 4 ๐Ÿ” 4 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
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a woman says " would you like to join us " with her eyes closed ALT: a woman says " would you like to join us " with her eyes closed

๐Ÿ“ข Open faculty position โ€“ Origins of Life
We have an opening in our section at the University of Geneva! ๐Ÿงฌ๐Ÿš€

SPREAD THE WORD

Apply here: jobs.unige.ch/www/wd_porta...

16.01.2026 17:49 ๐Ÿ‘ 45 ๐Ÿ” 39 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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New paper out!
We show how mechanosensitive adherens junction proteins link actomyosin contractility to actin assembly using in vitro reconstitution.
Huge congrats to Aurรฉlie Favarin, Rayan Said, & all authors!
In Science Advances: www.science.org/doi/10.1126/...
#actin #myosin #mechanobiology

02.01.2026 16:00 ๐Ÿ‘ 65 ๐Ÿ” 27 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 4

Yellow could be a two-spotted keyhole limpet, canโ€™t quite tell about the white one

31.12.2025 19:10 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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๐Ÿšจ POSTDOC OPENING ๐Ÿšจ
NIH-funded Bio-Fluid Mechanics Postdoc in my lab @univmiami.bsky.social
Hofstenia miamia | cilia-driven flows | behavior & neuroscience
Collab w/ Mansi Srivastava @harvard.edu
๐Ÿ•’ Start: Janโ€“Feb 2026
โณ 1 yr, renewable | Email me ASAP!
#Postdoc #Biophysics #FluidDynamics

23.12.2025 18:31 ๐Ÿ‘ 30 ๐Ÿ” 27 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

Congrats! Excited to read it

22.12.2025 14:53 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Decoding cnidarian cell type gene regulation - Nature Ecology & Evolution This study reconstructs the gene regulatory networks that define cell types in the sea anemone Nematostella vectensis, providing a valuable resource for comparative regulatory genomics and the evoluti...

Excited to share the final version of our study on Nematostella cell type regulatory programs. Part of our @erc.europa.eu StG project, this was a challenging 5-year effort extraodinarily led by @aelek.bsky.social and @martaig.bsky.social.

www.nature.com/articles/s41...

22.12.2025 10:12 ๐Ÿ‘ 107 ๐Ÿ” 37 ๐Ÿ’ฌ 8 ๐Ÿ“Œ 3
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The Church Evolution Lab (CEL@NYU) is hiring a postdoc! We have several new projects to study the genomic basis of biodiversity in model clades โ€“ย especially Hawaiian Drosophila. apply.interfolio.com/179354

Come join our new group, you can study bugs and live in NYC! Feel free to share widely!

22.12.2025 14:30 ๐Ÿ‘ 20 ๐Ÿ” 13 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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Happy holidays to one and all โ„๏ธ! On the Friday before Christmas ๐ŸŽ„ Iโ€™m excited to share my first first-author pre-print. Are you interested in molluscs ๐Ÿš, developmental biology, CRISPR F0 KOs, Pax6, eye ๐Ÿ‘๏ธ development and evolution? Then hereโ€™s a thread for you. www.biorxiv.org/content/10.1...

19.12.2025 15:37 ๐Ÿ‘ 14 ๐Ÿ” 4 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
Confocal microscopy image of a juvenile sea star (Patiria miniata) viewed from the oral side. The animal has a five-armed, star-shaped body with a central nerve ring. The nervous system is labeled in green, forming radial nerve cords extending into each arm, and cell nuclei are labeled in red throughout the animal. The image appears against a black background and has a holiday-ornament-like appearance.

Confocal microscopy image of a juvenile sea star (Patiria miniata) viewed from the oral side. The animal has a five-armed, star-shaped body with a central nerve ring. The nervous system is labeled in green, forming radial nerve cords extending into each arm, and cell nuclei are labeled in red throughout the animal. The image appears against a black background and has a holiday-ornament-like appearance.

Felt a little festive at the microscope this morning for #FluorescenceFriday ๐ŸŽ„

Hereโ€™s the nervous system of a juvenile sea star โญ๏ธ

Green = acetylated tubulin, red = nuclei

Happy holidays!

19.12.2025 17:32 ๐Ÿ‘ 579 ๐Ÿ” 131 ๐Ÿ’ฌ 11 ๐Ÿ“Œ 12

Congrats to you and the team! So cool to see this in its final form!

19.12.2025 14:36 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Self-folding laundry
Self-folding laundry YouTube video by PrakashLab

(1/n) What if you never had to make your bed? What if your laundry could fold itself? Folding is everywhere around us - but did you know that folding flat sheets are at the โค๏ธ of diversity of shapes in the animal world - since 500 million years ago. Our latest work: www.youtube.com/watch?v=nudC...

19.12.2025 07:47 ๐Ÿ‘ 47 ๐Ÿ” 15 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 4

๐Ÿ“ฃ #Job alert!
Looking to establish your own independent research in cell biology, development or evo-devo?
The @cnrs.fr is recruiting 7 scientists in that area of research.
Here are updated unofficial guidelines. Reach out to members of the committee if you have questions
c3n-cn.fr/section-24-w...

18.12.2025 08:52 ๐Ÿ‘ 42 ๐Ÿ” 36 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

18.12.2025 08:36 ๐Ÿ‘ 59 ๐Ÿ” 66 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 2
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

We are now advertising for the position of Assistant Professor of Marine Invertebrate Organismal Biology @uwsafs.bsky.social The position will be based out at Friday Harbor Labs in the San Juan Islands. See the ad below for details. @csucoast.bsky.social
apply.interfolio.com/178804

17.12.2025 18:40 ๐Ÿ‘ 8 ๐Ÿ” 11 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Congrats!! ๐Ÿพ

17.12.2025 14:45 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0