TAGHIVscience

Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success. Data source: https://report.nih.gov/nihdatabook/report/302

The data is in: the NIH goalposts have shifted.

What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards.

Another manifestation of how HHS policies have led to fewer awards and less science.

A ‘pre-obituary’ as protest by a long-term survivor in Florida

16,000 people living with HIV are expected to lose coverage from the AIDS Drugs Assistance Program due to Florida's funding cuts.

Read Kamaria Laffrey's pre-obituary as a long-term survivor in Florida.

"Kamaria Laffrey writes an indictment of a system that’s failing people living with HIV."

The guy who spent years writing articles like this is very confused about why you keep bringing up measles and vaccines.

At one point he said he overheard a security guard talking about bets made among the staff over which detainee would be next to die by suicide. The guard said he had paid $500 into a pool, with the total pot riding on the outcome. The talk was particularly jarring, he said, because he had contemplated suicide himself.

Indifference to suffering is a hallmark of genocide.

Attempted suicides, fights, pain: 911 calls reveal misery at ICE’s largest detention facility The calls to 911 poured in from staff at Camp East Montana, the nation's largest U.S. Immigration and Customs Enforcement detention facility, in its first months of operation in El Paso, Texas.

“Never again” is meaningless if it doesn’t include this. There’s no reason to mince words other than cowardice: these are concentration camps and never again is now.

Nashville Noticias' Estefany Rodríguez reportedly detained by ICE agents A reporter for Nashville Noticias was reportedly taken into custody by U.S. Immigration and Customs Enforcement agents Thursday afternoon.

ICE arrested a journalist yesterday without a warrant.

She is an asylum seeker, has valid work permits, and is married to a U.S. citizen.

fox17.com/news/local/n...

Leading psychiatrists are 'alarmed' that gender clinics refused to uphold really basic responsibilities of data stewardship, privacy and informed consent for research.

Trans communities do not hate research. We hate bad faith research designed to harm communities. 1/3

How Stand Up For Science is trying to 'pull every lever' to win over the public Stand Up For Science has become a formal organization and adopted a new strategy that's more confrontational with grassroots tactics

it feels like decades since the first Stand auto for Science protests

ahead of this year’s protests tomorrow, I caught up with @cdelawalla.bsky.social to talk about what @standupforscience.bsky.social sees as its strategy as a fully formed organization

www.statnews.com/2026/03/06/s...

I am shocked that a person who has spent the latter half of his career speaking about how awful medicine & public health are has not restored trust in medicine and public health.

Sepsis.
More people are going to die in their custody.

The DOJ Subpoenaed Patient Info From a Gender-Affirming Care Clinic. It Fought Back. A Washington judge quashed the Trump administration's attempt to subpoena patient information from the telehealth practice QueerDoc—but the fight may not be over.

Late last year I covered the case of QueerDoc, a small, telehealth gender-affirming care practice that received a subpoena from Trump's DOJ. The subpoena was blocked by a federal judge, but the DOJ appealed, and the 9th Circuit is hearing oral arguments today.

Take bold action to end TB! Email your members of Congress and telling them to take bold action to end TB!

Missed out on #TBHillDay but still want to participate in asking the US government to fund the fight against TB? The lovely people of @pih.org have just the tool for you! As a reward for clicking this link, you'll also get to see my funny face squinting at the sun!

nwmd.social/s/copylink/4...

Hour-scale single-molecule imaging reveals dynamic assembly of the Wnt co-receptors LRP6 and ROR2 into common signalosomes A method that extends the duration of single-molecule tracking provides insights on Wnt receptor dynamics.

In #ScienceSignaling, a team of scientists devises a method to extend the time that individual molecules can be tracked in a cell, widening the analysis window from several seconds to more than one hour. https://scim.ag/3OGClH4

Supreme Court Abuse of the Shadow Docket Under Trump The Court has sided with the administration 80 percent of the time when making “emergency” rulings, often without revealing its reasoning.

The Supreme Court should be a bulwark for the rule of law. Instead, it’s abusing the “shadow docket” to break with precedent and expand presidential powers in unprecedented ways. bit.ly/4cybln3

Thread. You can’t trust the Trump/RFK/Bhattacharya regime, even when they make representations to courts.

#Trump and #RFKJr's handiwork: "This is thousands of women not getting pain control or not getting fever reduction when they need it, when they want it, when they would benefit from it," Faust says. https://www.npr.org/2026/03/05/nx-s1-5732929/tylenol-pregnant-women-autism-trump-warning

African paediatric studies at CROI: HIV remission in children, three bNAbs in babies, two years on injectables in teens A number of innovative approaches to treating children were presented at last week’s Conference on Retroviruses and Opportunistic Infections (CROI 2026) in Denver, US.&nbsp;Several were based on the fact that infants have good prospects for long-term viral suppression without antiretroviral therapy (ART). Failing that, children and adolescents, who may have particular problems with adherence to daily pills, are prime candidates for long-acting injectable formulations.

African paediatric studies at #CROI2026: HIV remission in children, three bNAbs in babies, two years on injectables in teens

TB advocates in a congressional office

TB advocates in a congressional office

TB advocates in a congressional office

TB advocates in a congressional office

Diane represented the great state of Ohio & #tuberculosis survivors everywhere in her meetings on TB Hill Day! Thank you to the offices of Rep. Guy Reschenthaler, Sen. John Husted,
@berniemoreno.bsky.social
and Rep. Joyce Beatty for meeting with Diane & the TB Roundtable! #SwagLikeOhio #TBhillDay

2026 Pre-CROI Community HIV Cure Research Workshop – Treatment Action Group BSVC Director Richard Jefferys coordinated this annual workshop that brings together advocates, researchers, and community members for presentations and discussions on HIV cure-related research just b...

Recordings and slides from the 2026 Pre-CROI Community #HIV Cure Research Workshop www.treatmentactiongroup.org/webinar/2026... #CROI2026

Chanting activists hang banners from Cannon House Rotunda

Chanting activists hang banners from Cannon House Rotunda

Chanting activists hang banners from Cannon House Rotunda

Chanting activists hang banners from Cannon House Rotunda

#BREAKING: 13 arrested in Cannon House Rotunda demanding immediate release of $977 million in PEPFAR funding illegally impounded by Vought, read: bit.ly/PEPFARSlowDown

and press release: healthgap.org/press/activi... @housingworksnyc.bsky.social @treatmentactiongroup.org

Current NIH leadership want you to think they are using rigorous, consistent & scientific processes to screen studies to align them with agency priorities.

But the process that they have put down on paper is a sham.

It’s important to know NIH is not following its own guidance. Here’s why:

🧵1/

One pediatrician “testified that she had witnessed children’s medical treatment, sometimes in the middle of chemotherapy, disrupted because their parents had been detained or deported by ICE … there is no insurance plan, no transportation to the hospital, no one to pick up prescriptions.”

Tracking the "America First" Bilateral Health Agreements | Think Global Health Think Global Health's analysis found gaps between country needs and new cofinancing commitments with the United States

For anyone interested in global health this is a phenomenal tracker of the America first MOUs which are defining a new era of US global health engagement.
www.thinkglobalhealth.org/article/trac...

Just part of all the attacks on federal workers and their unions.

And remember a whole bunch are likely to lose their protections next week when the list of who becomes schedule F is released.

Breaking:

WASHINGTON (AP) - More than 20 states sue over new global tariffs Trump imposed after Supreme Court loss.

Explore Financial Disclosures From President Trump and 1,500 of His Appointees - ProPublica Use this database to explore potential conflicts of interest for President Donald Trump and his team. The documents disclose positions officials have held outside government, their assets and their de...

NEW: Use our database to explore the financial disclosures of President Donald Trump and more than 1,500 of his appointees.

Biotech investor set to lead US National Science Foundation If confirmed by the US Senate, Jim O'Neill would be the first non-scientist or engineer to lead the agency, a big funder of US basic research.

O'Neill, an investor in anti-aging technology who worked on HHS policy, would be the first non-scientist or engineer to lead NSF. His background will be a 'major concern' to the science and technology community, former NSF director Neal Lane told me.

@maxkozlov.bsky.social and I report:

screen cap of NYT home page

Aside from one brief mention of @zohrankmamdani.bsky.social's opposition way down in the corner, the 2/3 of Americans who oppose the Iran War have had zero representation on the NYT home page news section this entire week

excellent deep dive into all of the ways that the Trump administration has used the federal budget to keep punishing critics and trying to bend them to his will. FWIW, this is precisely how Viktor Orban crushed the opposition in Hungary 15 years ago. The national budget is a powerful weapon.

Annenberg: Stark Divide: Americans More Confident in Career Scientists at U.S. Health Agencies Than Leaders

@appc.upenn.edu
CDC HHS FDA NIH

bit.ly/4bbM0gd