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Cryo Mariena

@cryomariena

I like big scopes + I cannot lie. Struct bio + mat sci. Boricua. Pastafarian. Opinions = my own. #cryoeming since 2004. She/Her

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03.07.2023
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Latest posts by Cryo Mariena @cryomariena

Thing I may have said to @davidamuller.bsky.social today: I didn't lick the board, just did a sniff test. But I did lick the copper. Because when you were trained in bio, you may lick or sniff things out of scientific curiosity πŸ˜†

28.02.2026 02:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Why have a red light, when your stage can have a blue light?

27.02.2026 18:33 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Awww thank you for those kind words ☺️☺️

27.02.2026 13:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

That said, the detector is still misbehaving, so, I anticipate more grey hairs and repeated bargaining with the devil to make me dumb and useless, because it can be frustrating when stuff behaves badly.

27.02.2026 02:03 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I just never considered I'd become or be part of that institutional memory. It is a great responsibility.

27.02.2026 02:02 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I've become some sort of institutional memory and I don't know how I feel about this. I now know why we try to keep personnel happy and engaged, so that when things go kaput, said personnel deploys fixes.

27.02.2026 02:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

While trying to set said detector right, I mused about what would happen if I died. Given that the other half of the nuclear duo is not in this realm anymore (yes, Lena was my other/better half when it came to that equipment).

27.02.2026 02:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I never thought my scientific children would call me the nuclear option. Apparently my future boss has also called me that (in my hulble opinion, SHE is THE nuclear option).

27.02.2026 01:58 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

We have a misbehaving detector which has caused many of my hairs to turn grey. Well, my students know how to troubleshoot said detector. I was today years old when I learned I am known as ... THE NUCLEAR OPTION because I (try) to help said detector behave.

27.02.2026 01:57 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Hugs!!!

27.02.2026 01:56 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I'm glad you've experienced prolonged relief from those horrible migraines. It's understandable why the whole day goes kaput.

25.02.2026 01:39 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme?
Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues.
Apply by 16 MAR
www.nature.com/naturecareer...

24.02.2026 09:45 πŸ‘ 36 πŸ” 48 πŸ’¬ 0 πŸ“Œ 2

So .... the Epstein files were his breaking point? Huh .... I'm glad he abandoned that ship.

25.02.2026 01:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
RNA Society

The most important #RNA conference of the year with lots of amazing science and a really friendly atmosphere. This year in beautiful Montreal πŸ‡¨πŸ‡¦ !

www2.rnasociety.org

24.02.2026 12:05 πŸ‘ 20 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0

When you remember how to troubleshoot you first baby in the silliest of ways. But hey, it worked! Who am I to question my methods? 🀣🀣

24.02.2026 17:09 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Senior Scientist, Protein Sciences in South San Francisco, California, United States of America | Research & Development at Genentech Apply for Senior Scientist, Protein Sciences job with Genentech in South San Francisco, California, United States of America. Research & Development at Genentech

Our department at Genentech is hiring. We're looking for a freshly-minted PhD (0-3 years) protein biochemist / structural biologist to join as a Sr Scientist. A rare opportunity to join our group leader job family at a more junior level than we usually hire.

24.02.2026 16:55 πŸ‘ 55 πŸ” 57 πŸ’¬ 2 πŸ“Œ 0
Preview
Thermophilic bacteria employ a contractile injection system in hot spring microbial mats Abstract. Bacterial contractile injection systems (CISs) are multiprotein complexes that facilitate the bacterial response to environmental factors or inte

Contractile Injection Systems - Hot Springs - cryoET: Read the final version of our paper here:
academic.oup.com/ismej/advanc...
#microsky #teamtomo

11.02.2026 14:43 πŸ‘ 27 πŸ” 9 πŸ’¬ 0 πŸ“Œ 1

I'm so sorry, friend. What happened? Are you OK? Hugs if you're in need of one or a few.

12.02.2026 19:38 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Awww. When guests come and bring goodies from our friendly neighbours upstairs. I miss the kindness of Canada. And I absolutely adore how excited they seem to be at the fact that Benito included them in the show.

12.02.2026 19:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

And that was also one of the promises Lena made when I started here. She said: you'll learn to diagnose issues because the FSEs come from faraway places and we want them to have as much info about the issue they're coming to tackle as they can. And again, she was right.

11.02.2026 22:48 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Half joking. I'm. Toys r Us kid. I don't want to grow up. That, and the fact that the boss and sub-bosses always encourage curiosity and learning to troubleshoot like FSEs.

11.02.2026 22:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

When you manage to fix an issue for a FSE in a couple of mins, without needing to restart a single thing. And the FSE says: that's very impressive. And I say, when I grow up I want to be like you 😁.

11.02.2026 22:44 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Happy Women in science day. On this day I am thinking of all my women science mentors and Rita Levi-Montalcini who did experiments in her bedroom in defiance of Mussolini’s ban on Jews in academic and professional careers while WWII raged around her.

11.02.2026 20:41 πŸ‘ 44 πŸ” 18 πŸ’¬ 1 πŸ“Œ 2

Your mom better have a nice, full resolution picture of certain Guiness World Record picture on her refrigerator!

11.02.2026 20:08 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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About the only thing I feel like celebrating right now (well, along with doing a semi flawless cryo insertion)

11.02.2026 00:45 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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National Academy of Engineering Elects 130 Members and 28 International Members The National Academy of Engineering (NAE) today announced the election of 130 members and 28 international members to its Class of 2026, said NAE President ...

Many congrats to our fearless leader @davidamuller.bsky.social www.nae.edu/19579/31222/...

11.02.2026 00:39 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

I still got it. Doing a cryo insertion for the first time this year and it went beautifully. 22yrs and it's still there *chef's kiss.*

10.02.2026 22:32 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
"Let's align our coordinates" valentine with Oxytocin receptor ("love hormone") aligned with vasopressin receptor

"Let's align our coordinates" valentine with Oxytocin receptor ("love hormone") aligned with vasopressin receptor

Use RCSB PDB's Pairwise Structure Alignment tool to compare existing PDB structures or Computed Structure Models (or upload a local file) #LoveDataWeek
www.rcsb.org/alignment

10.02.2026 17:22 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 2
Bad Bunny in a field
Light poles behind him

Bad Bunny in a field Light poles behind him

For those unaware about the significance of the light poles during the song El ApagΓ³n it’s because of the Puerto Rican power system and the constant black outs. There have been a lot of protests on the island over this.

09.02.2026 02:24 πŸ‘ 668 πŸ” 143 πŸ’¬ 10 πŸ“Œ 6

Elmo
@elmo
Β·
1h
That Bunny was AMAZING. Elmo thinks he should be called Good Bunny! Elmo loves you, Mr. Good Bunny! ❀️🎢🐰
Based Yankee
@thebasedyankee
You and Bad Bunny should be deported

Elmo @elmo · 1h That Bunny was AMAZING. Elmo thinks he should be called Good Bunny! Elmo loves you, Mr. Good Bunny! ❀️🎢🐰 Based Yankee @thebasedyankee You and Bad Bunny should be deported

It's not even midnight and we're already at "Deport Elmo."

09.02.2026 03:15 πŸ‘ 42738 πŸ” 7468 πŸ’¬ 991 πŸ“Œ 548