MaP-Proteomique

I am thrilled to share the final programme for the upcoming Annual Proteomics Gathering organized by @ypic.bsky.social in Madrid. Check out the QR to see the full list of speakers and talks themes. It looks like a very promising event! 👩🏻‍🔬🔬🎓 Looking forward to welcome all the attendees on April 16th!

Phosphorylation-driven signaling plays a central role in how cells communicate. In this study, together with @saezlab.bsky.social , we revisit the EGF signaling pathway and ask: How well does our traditional understanding hold up in the era of modern phosphoproteomics? www.nature.com/articles/s41...

@map-proteomique.bsky.social was delighted to present its expertise at the first edition of the @crcm.bsky.social Symposium (Centre de Recherche en Cancérologie de Marseille), with contributions from Célia Jardin and Émilie Baudelet

@map-proteomique.bsky.social was delighted to present its expertise at the first edition of the @crcm.bsky.social Symposium (Centre de Recherche en Cancérologie de Marseille), with contributions from Célia Jardin and Émilie Baudelet

Once again a great collaboration with @ibmm-balard.bsky.social @map-proteomique.bsky.social and other !!!

We’re excited to announce the arrival of our new @brukercorporation.bsky.social timsTOF HT — engineered for deeper, faster proteomic discovery at the IMM proteomics platform, part of @map-proteomique.bsky.social

In the heart of winter, the mimosa blooms like fireworks, celebrating the arrival of the New Year.

Happy new year from Marseille proteomics @map-proteomique.bsky.social. Wishing you a great end of year. New year, new projects - follow us in 2026!

Season’s greetings from MAP @map-proteomique.bsky.social. Wishing you happy holidays and a great end of year. New year, new projects - follow us in 2026!

Syntenin Controls Extracellular Vesicle-Induced Tumour Migration by Regulating the Expression of Adhesion Proteins on Small Extracellular Vesicles - PubMed Despite extensive proof for the tumour-supporting function of cancer-derived small extracellular vesicles (sEVs), attributions of pathological effects to specific sEV subpopulations are poorly described. In this study, we aimed to characterise a distinct sEV species under the control of Syntenin, a …

New paper from @crcm.bsky.social & @map-proteomique.bsky.social , in collaboration with the @uni-muenster.de and @uni-goettingen.de !📄🔗 pubmed.ncbi.nlm.nih.gov/40831280/
Excited to have contributed to this work!

📢Publication Alert🌶️! The human cell line phosphoproteome ATLAS has just been released! Generated by analysing 33 human cell lines the team regroup over 200,000 class I phosphosites! Congratulations to @jesperolsenlab.bsky.social! #MagReSyn #Phosphoproteomics #samplepreparation

Proteomics analysis of flow cytometry-based isolated pathogen-containing phagosomes at The University of Manchester on FindAPhD.com PhD Project - Proteomics analysis of flow cytometry-based isolated pathogen-containing phagosomes at The University of Manchester, listed on FindAPhD.com

I have a PhD position available with start date September 2026 at the University of Manchester.

Proteomics analysis of flow cytometry-based isolated pathogen-containing phagosomes

Due to funding requirements, this position is for UK home students only.

www.findaphd.com/phds/project...

Evosep Curiosity Days I Amsterdam, Netherlands Curious on Evosep technology and its applications? Expand your knowledge on February 5 at Evosep Curiosity Days in Amsterdam, Netherlands.

Save the date: February 5th, 2026 for Evosep’s Curiosity Day in Amsterdam.

Expect an exiting full-day program of knowledge sharing, networking, and opportunity to learn more about Evosep technology.

Register here: evosep.com/evosep-curiosity-days-amsterdam-netherlands

A big thanks to Matteo Levy for taking a break from his Master’s exam preparations next week to share, at the monthly MaP meeting, his research conducted during his apprenticeship at @map-proteomique.bsky.social @crcm.bsky.social. An exciting topic: the development of immunopeptidomics!

E-Cadherin Is a Structuring Component of Invadopodia in Pancreatic Cancer - PubMed The appearance of hybrid epithelial-mesenchymal (E/M) cells expressing E-cadherin is favourable for the establishment of pro-invasive function. Although the potential role of E-cadherin in cancer invasion is now accepted, the molecular mechanisms involved in this process are not completely elucidate …

🧬 New from @crcm.bsky.social & @map-proteomique.bsky.social! Dobric A. et al., pubmed.ncbi.nlm.nih.gov/40366255/ J Cell Mol Med 2025: E-Cadherin is a key structural component of invadopodia in pancreatic cancer. Excited to have contributed! 🔬 #PancreaticCancer #CellBiology

@map-proteomique.bsky.social is pleased to present today at the first joint symposium bringing together the prestigious research centers @ciml.bsky.social and @crcm.bsky.social

Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...

Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏

www.biorxiv.org/content/10.6...

I don't know about a lot of things, but I didn't know about thermal proximity coaggregation (TPCA), or maybe I did. Still, dig it.

www.science.org/doi/10.1126/...

The Human Cell Line Phosphoproteome Atlas: A Deep Empirical Resource Revealing Kinase Activity Landscapes www.biorxiv.org/cont...

---
#proteomics #prot-preprint

Isobaric labeling with the @thermofishersci.bsky.social TMT kit is super useful in proteomics! 🧬🔥
#Proteomics #TMT #MassSpec #ScienceLife

Isobaric labeling with the @thermofishersci.bsky.social TMT kit is super useful in proteomics! 🧬🔥
#Proteomics #TMT #MassSpec #ScienceLife

I will be at the 𝐃𝐈𝐀-𝐍𝐍 session @ 𝐓𝐡𝐞𝐫𝐦𝐨 𝐏𝐫𝐨𝐭𝐞𝐨𝐦𝐞 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐞𝐫 & 𝐂𝐨𝐦𝐩𝐨𝐮𝐧𝐝 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐞𝐫 User Meetings in Bremen, Germany, 𝟗-𝟏𝟏 𝐃𝐞𝐜𝐞𝐦𝐛𝐞𝐫. With some cool advances for DIA-NN on Thermo instruments. www.thermofisher.com/de/de/home/e...

Great to welcome Sébastien JeanJean, Senior Sales Manager France at @thermofishersci.bsky.social, to visit our new #OrbitrapAstral mass spectrometer installation today!
Big thanks to our funders — CPER, LNCC, @ibisa.net, Amidex, and @inserm.fr.
#MassSpec #Proteomics @insermpacacorse.bsky.social

Great to welcome Sébastien JeanJean, Senior Sales Manager France at @thermofishersci.bsky.social, to visit our new #OrbitrapAstral mass spectrometer installation today!
Big thanks to our funders — CPER, LNCC, @ibisa.net, Amidex, and @inserm.fr.
#MassSpec #Proteomics @insermpacacorse.bsky.social

In DIA-NN 2.3.0, we have added Deamidation (NQ) as an option in the GUI. There are good reasons for it :) You can try InfinDIA with any number of modifications selected, and check the RT differences between modified vs respective stripped peptides, for each mod - a way to validate peptidoform FDR.

With 𝗗𝗜𝗔-𝗡𝗡 𝟮.𝟯.𝟬 Preview (Academia-only for now), we showcase the transformative new capabilities that have been developed in the past months. Download: github.com/vdemichev/Di...

Recognition of Ovarian Tumor-Derived Non-canonical Peptide Induces Memory-Like Features in Natural Killer Cells Immune cell-based immunotherapy has emerged as a promising strategy for both hematologic malignancies and solid tumors. The adaptive properties of T and B cells, namely, antigen specificity and long-t...

🚨Publication alert🌶️: #Immunopeptidomics is a trending for good reason! A team from @ki.se identify ovarian tumor-derived peptide that induces memory-like features in natural killer cells, paving the way for new cancer immunotherapy strategies! www.biorxiv.org/content/10.1...

Recommendations for Quantitative Data-Independent Acquisition (DIA) Proteomics using Controlled Quantitative Experiments (CQEs) Advances in mass spectrometry and associated computational tools have resulted in the wide-spread adoption of Data-Independent Acquisition (DIA) for proteomics. Experiments using state-of-the-art inst...

Are you using DIA mass spectrometry in proteomics?

We have just put this paper online: www.biorxiv.org/content/10.1...

Here, we came up with some Recommendations for Quantitative Data-Independent Acquisition (DIA) Proteomics using Controlled Quantitative Experiments (CQEs)

1/4

Proteomics Webinar: DIA with FragPipe, DIA-NN, and Skyline
Presenters: Eduard Sabidó and Brendan MacLean
When: Tuesday, September 16, 8am (Pacific Time)
Register Now ... skyline.ms/project/home...

#massspec #proteomics

@kentsisresearch.bsky.social develop a proteogenomics workflow to detect 1000s of unknown cancer proteins. PG3 combines long-read RNA sequencing with multi-protease MS to discover non-canonical proteins in cancer cells. Used a timsTOF HT, nanoElute 2 & Aurora Ultimate 25x75 column:
bit.ly/4mlQSmu