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Dennis Maharjan

@dennismaharjan

Neuroscientist at the Allen Institute.

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03.12.2024
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Latest posts by Dennis Maharjan @dennismaharjan

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I still get chills

Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts

Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE

see videos, read paper, follow thread
doi.org/10.31234/osf...

10.08.2025 18:22 ๐Ÿ‘ 390 ๐Ÿ” 136 ๐Ÿ’ฌ 17 ๐Ÿ“Œ 34

Congratulations Arka!!

20.06.2025 20:19 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

I pass by that cart everyday to the Allen! The bananas are free for anyone to grab btw.

Hope you enjoy the meeting!

23.04.2025 19:00 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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โœจ Announcing a new glutamate indicator - iGluSnFR4! โœจ

Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.

More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...

๐Ÿง ๐Ÿ“ˆ

25.03.2025 22:24 ๐Ÿ‘ 117 ๐Ÿ” 26 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 5

Excited to share that our paper is now published in Nature! In this study, we uncovered a grid-cell-based circuit in medial entorhinal cortex that probes the surrounding environment with theta-paced, sweeping spatial representations ๐Ÿงต
www.nature.com/articles/s41...

04.02.2025 21:12 ๐Ÿ‘ 83 ๐Ÿ” 23 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 0
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I had so much fun ushering in the Year of the Snake with everyone at the @alleninstitute.bsky.social. Thank you to Mak Fai Lion Dance putting on such a great show.

Wishing you all a year of health and prosperity!
#LunarNewYear #YearOfTheSnake

31.01.2025 17:02 ๐Ÿ‘ 9 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

Congrats Diego!!

26.01.2025 00:50 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal identity and reward contingency signals during rule-reversal - Nature Communications Hernandez-Trejo, Ciuparu, and Garcia da Silva et al. report that the piriform-to-olfactory bulb feedback in the mouse carries multimodal identity and reward contingency signals, which are re-formatted...

New paper from the lab: feedback from piriform cortex to the olfactory bulb carries identity and reward contingency signals in a multimodal (odor and sound) rule-reversal task. Feedback is re-formatted within seconds and reflects changes in the perceived rules of engagement.
doi.org/10.1038/s414...

23.01.2025 11:27 ๐Ÿ‘ 52 ๐Ÿ” 18 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 0