Metaorganism Research

Virtual Colon: spatiotemporal modeling of metabolic interactions in a computational colonic environment | mSystems Interactions between the human body and gut microbes are crucial for health and disease. We present the Virtual Colon, an extension of the individual-based microbiome modeling approach BacArena that m...

(1/7) Excited that the Virtual Colon, an extension of BacArena for modeling the spatiostructural environment of the colon, is now out at mSystems. Kudos to @maringos.bsky.social and for leading this work! @crc1182.bsky.social @uni-kiel.de iel.de Link: journals.asm.org/doi/full/10....

Final day of the @uni-kiel.de #CRC1182 2025 retreat today at @geomarkiel.bsky.social. Many thanks to all participants!

More information and some images:
www.metaorganism-research.com/news/crc-118...

Applying evolutionary theory to understand host–microbiome evolution - Nature Ecology & Evolution This Perspective discusses how well-established theoretical models of evolution can be adapted to study and generate testable predictions about the evolutionary dynamics of host–microbiota association...

I am happy to announce publication of our new perspectives paper on applying evolutionary theory to host-microbiome evolution - new tricks for old dogs! @bweek.bsky.social @uni-kiel.de @transevo.bsky.social @crc1182.bsky.social www.nature.com/articles/s41...

W 3 professorship in Molecular and Evolutionary Zoology - Kiel, Schleswig-Holstein (DE) job with Christian-Albrechts-Universität zu Kiel | 12844416 Kiel University aims to attract more qualified women to professorship positions. The Institute of Zoology at the Faculty of Mathematics and Natural...

We are welcoming applications for a full professorship on Molecular and Evolutionary Zoology at Kiel Univerdity, Northern Germany, with fantastic facilities and infrastructure! @uni-kiel.de @crc1182.bsky.social @transevo.bsky.social www.nature.com/naturecareer...

Teaching old dogs new tricks: Extending existing theory on #host-microbiome evolution. New #CRC1182 publication out in @natecoevo.nature.com in cooperation with Brendan Bohannan, Shelbi Russell and Marjolein Bruijning:
www.metaorganism-research.com/news/teachin...

The Interaction Between the Nematode Caenorhabditis elegans and Its Coexisting Fungal Microbiome Member Barnettozyma californica Barnettozyma californica is a member of the fungal microbiome of the model nematode Caenorhabditis elegans and can serve as food for worms. When combined with E. coli, this fungus can increase popula...

See our new paper on C. elegans-yeast interactions. @crc1182.bsky.social @michaelhabig.bsky.social enviromicro-journals.onlinelibrary.wiley.com/doi/full/10....

Role of microbial life history strategy in shaping the characteristics and evolution of host-microbiota interactions Abstract. Many host-associated microbes are transmitted between individual hosts via the environment and, therefore, need to succeed both within a host and

And also see our new paper on the Role of microbial life history strategy in host-microbiome interactions in the ISMEJ. @crc1182.bsky.social url: academic.oup.com/ismej/articl...

Mercator Fellows visit life sciences at @uni-kiel.de:
@jessmetcalf.bsky.social and Brendan Bohannan are currently contributing to our research activities as guests of @transevo.bsky.social and #CRC1182. Many thanks to both of you for staying with us!
www.metaorganism-research.com/news/mercato...

#CRC1182 Summer get-together coming up next week:
Join us on Thursday, July 31st, at the Biozentrum, everyone from the CRC 1182 is warmly invited! More information:
www.metaorganism-research.com/seminars-eve...

Multi-omics analysis highlights the link of aging-related cognitive decline with systemic inflammation and alterations of tissue-maintenance Aging-related cognitive decline is associated with changes across different tissues and the gut microbiome, including dysfunction of the gut-brain axis. However, only few studies have linked multi-org...

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🧠 Excited to share our new preprint on molecular drivers of cognitive function in aging mice!
Led by Stefano Flor & @sciwitch.bsky.social, with the Frahm lab @uni-kiel.de @crc1182.bsky.social
📄 www.biorxiv.org/content/10.1...

The @symbnet.bsky.social‬ PhD Summer School 2025 on #host-microbe symbioses at Oeiras, Portugal, supported by the #CRC1182 just ended. We collected some impressions:
www.metaorganism-research.com/news/6th-edi...

Winning Best Poster Award is always exciting — but receiving it at the SymbNet Summer School feels truly unbelievable! 🚀


The level of expertise from the faculty was sky-high, and the talent of students made me feel like I need to work more to keep up 😱

#SymbNet #ScienceCommunity #BestPosterAward

Register now: Performing Arts & Science Conference, July 16-17 in Kiel, supported by the #CRC1182 amongst others.

The Performing Science Conference brings together experts from the natural sciences and the performing arts in a dialog at eye level. More info and registration: performing-science.de

From microbes to molecules: unveiling host-microbe interactions with spatial metabolomics | Molecular Systems Biology EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

Happy to share our new comment on How #spatial #metabolomics is transforming #microbiology and gives insights into #microbe-microbe and #host-microbe interactions. #OpenAccess in @molsystbiol.org @crc1182.bsky.social @uni-kiel.de @mpimarinemicrobio.bsky.social doi.org/10.1038/s443...

© Jan Steffen

© Jan Steffen

© Jan Steffen

The #CRC1182 was represented again at the 2025 #KielerWoche together with KLS and PMI Cluster of Excellence. Here are a few images from the #KielerUniLive @uni-kiel.de event featuring our Digital Meta Poster, Sponge Pop-Up Cards and more:
www.metaorganism-research.com/news/crc-118...

© Christopher Noack

New work from Bosch Lab's @chnoack.bsky.social et al:
How the nerve network in the freshwater polyp Hydra self-organises during embryonic development under the influence of environmental factors including the #microbiome
www.metaorganism-research.com/news/observi...

Assembly of a functional neuronal circuit in embryos of an ancestral metazoan is influenced by temperature and the microbiome | PNAS Understanding how neural populations emerge to give rise to behavior is a major goal in neuroscience. Here, we explore the self-assembly of neural ...

I am excited to share our new publication in @pnas.org on the de novo nerve net assembly in Hydra embryos showing that neural circuits self-assemble through activity-driven processes, modulated by temperature and the microbiome. Thanks to all colleagues involved here! www.pnas.org/doi/10.1073/...

Polyketide synthase-derived sphingolipids mediate microbiota protection against a bacterial pathogen in C. elegans - Nature Communications Here, Peters et al. report that Pseudomonas fluorescens protects Caenorhabditis elegans against pathogen infection via polyketide synthase-derived sphingolipids, uncovering a non-canonical bacterial s...

See our new paper, headed by Katja Dierking and her team, esp. Lena Peters, on microbiota protection against pathogens @crc1182.bsky.social @uni-kiel.de @manuelliebeke.bsky.social @kaletalab.bsky.social doi.org/10.1038/s414...

The #CRC1182 metaorganism symposium on cellular #host-microbe crosstalk has just come to an end @geomarkiel.bsky.social
Thanks to all for participating and special thanks to @utehentschel.bsky.social for organizing this wonderful event!
www.metaorganism-research.com/news/cellula...

The 1st talks of our #metaorganism symposium in Kiel have been eye opening and fascinating! Microbes interacting with worms, squid, plants and jellyfish - so much novel cross talk shown. #symbiosis @crc1182.bsky.social

#CRC1182 two day symposium on "Cellular Underpinnings in #Host-Microbe Crosstalk" starting tomorrow:
www.metaorganism-research.com/seminars-eve...

Looking forward to an exciting CRC 1182 Metaorganism symposium on host-microbe crosstalk. @crc1182.bsky.social @cpogoreutz.bsky.social @spencernyholm.bsky.social @manuelliebeke.bsky.social oliviaroth.bsky.social @tylerjcarrier.bsky.social @geomarkiel.bsky.social @daganlab.bsky.social

Thomas Bosch zum Leopoldina-Mitglied ernannt Nationale Akademie der Wissenschaften ehrt CAU-Professor für die Erforschung der Wirts-Mikroben-Beziehungen

Die Leopoldina beruft Prof. Thomas Bosch, Zell- und Entwicklungsbiologie an der #UniKiel, zu ihrem neuen Mitglied. Die Nationale Akademie der Wissenschaften ehrt ihn für herausragende Leistungen in der Erforschung der Wirts-Mikroben-Beziehungen und ihrer Bedeutung für Gesundheit und Krankheit:

We are exploring the physiological and evolutionary adaptations of plants to various stress factors in aquatic and terrestrial ecosystems.

A key focus is understanding the central role of the microbiome—the microorganisms residing in/on plants—in the development of plant stress defense mechanisms.

Life-long microbiome rejuvenation improves intestinal barrier function and inflammaging in mice - Microbiome Background Alterations in the composition and function of the intestinal microbiota have been observed in organismal aging across a broad spectrum of animal phyla. Recent findings, which have been der...

Life-long microbiome rejuvenation to delay aging? New #CRC1182 supported work by
@microbiomefxn.bsky.social, @kaletalab.bsky.social and Philip Rosenstiel et al. out in Microbiome:
doi.org/10.1186/s401...

Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice - Nature Microbiology A multi-omics approach reveals host–microbiome interactions in aging in mice.

Current paper by @kaletalab.bsky.social et al. in @naturemicrobiol.bsky.social on host-microbiome-interactions in aging, supported by the #CRC1182:
doi.org/10.1038/s415...

And here is a press release covering our work on host-microbiome-interactions in aging: www.precisionmedicine.de/de/das-mikro...

Neues Evolutionsforschungszentrum am Bremerskamp nimmt Gestalt an Im Center for Fundamental Research in Translational Evolutionary Biology (CeTEB) werden ab 2027 Forschungsprojekte zur Evolutionsforschung bearbeitet. Heute wurde gemeinsam mit den Handwerkern das Ric...

Another step closer to our new #research building on #translational #evolutionary #biology at @uni-kiel.de. Thanks to everyone involved in the realization of this fantastic new research environment
www.gmsh.de/pressemittei...

PhD Summer School on Host-Microbe Symbioses 2025 Symbnet PhD Summer School on Host-Microbe Symbioses Gulbenkian Institute for Molecular Medicine (GIMM) & Católica Biomedical Research Centre (CBR) July 06...

Registrations are open for the SymbNET PhD Summer School on Host-Microbe Symbioses 2025. 6-19 July 2025 in Oeiras, Portugal.

@gimmfoundation.bsky.social #CBR Católica Biomedical Research Centre @moorefound.bsky.social @crc1182.bsky.social #CIFAR

gimm.idloom.events/phd-summer-s...

Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice - Nature Microbiology A multi-omics approach reveals host–microbiome interactions in aging in mice.

1/12 Thrilled to share our latest paper on host-microbiome-interactions in aging out in Nature Microbiology @naturemicrobiol.bsky.social, great work led by Lena Best @sci-witch.bsky.social with the Frahm lab within the ITN SmartAge. @crc1182.bsky.social @uni-kiel.de
www.nature.com/articles/s41...