Leslie Day, PhD's Avatar

Leslie Day, PhD

@lesliedaymicro

Anaerobic Microbiologist Damon Runyon Fellow Postdoc @ O’Toole Lab, Dartmouth

56
Followers
69
Following
23
Posts
13.06.2025
Joined
Posts Following

Latest posts by Leslie Day, PhD @lesliedaymicro

Post image

Our newest paper by Sarvesh Surve, a PhD student in the lab, explores the culturome of the regions of the gut for persons with CF. We see clear differences from healthy controls, esp. in the mucosal samples.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

02.03.2026 22:22 👍 9 🔁 3 💬 0 📌 1
Post image

Excited about a recent paper from Bassam el Hafi, a recently graduated PhD student, & Fabrice Jean Pierre leveraging 4,200 respiratory microbiomes from CF (pre- and post-ETI), and testing one of the hypotheses that arose from this analysis.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

27.02.2026 20:19 👍 8 🔁 4 💬 1 📌 2
Preview
What does that have to do with cancer? Current and former Damon Runyon scientists explain why breakthroughs can come from unusual places, and why Damon Runyon's funding strategy is so important.…

Major breakthroughs in cancer research can come from the most unexpected sources. This World Cancer Day, we celebrate the curiosity that drives our scientists to look for answers in unusual places.

04.02.2026 22:09 👍 1 🔁 1 💬 0 📌 0
Preview
The disputed identity of Pseudomonas putida KT2440: when taxonomists rename your favorite microbe | mBio Names matter; they are not mere labels. They operate as anchors of memory, social coordinates, and references of collective identity. When a name becomes established through long-term use and broad ad...

A must read! The constant and often irrational renaming of microbes is out of control, and bad for microbiology and microbiologists.
journals.asm.org/doi/10.1128/...

28.01.2026 19:02 👍 13 🔁 5 💬 0 📌 1

The Microbial Diversity courseis top-notch! Hoping to see you there! www.mbl.edu/education/ad...

14.01.2026 18:44 👍 2 🔁 3 💬 0 📌 0

Good luck!

08.01.2026 21:45 👍 1 🔁 0 💬 0 📌 0

What temp do you grow them up from the colony?? I’ve found this happens less if I grow at a lower temp 30 v 37

08.01.2026 21:00 👍 1 🔁 0 💬 1 📌 0

@smartalyk.bsky.social

04.01.2026 12:50 👍 1 🔁 0 💬 1 📌 0
Preview
Damon Runyon scientists on the impact of slashing research funding Damon Runyon scientists explain how drastic cuts in federal research funding threaten progress in cancer research, and how Damon Runyon can help protect the breakthroughs…

No one organization can fill the gaps created by federal funding cuts to research. But as an independent funder, Damon Runyon is committed to ensuring that our scientists can continue their lifesaving work in 2026 and beyond. Until midnight, all gifts will be fully matched: damonrunyon.org/donate

31.12.2025 18:07 👍 3 🔁 2 💬 0 📌 0
Post image

New from AFI researchers Jennifer Gundrum and Drs. Tabita Ramirez-Puebla, Jessica L. Mark Welch, and Gary G. Borisy:

Novel FISH method overcomes cell wall barriers, enabling clearer insight into complex microbial communities.

Learn more: journals.asm.org/doi/10.1128/...

23.12.2025 14:50 👍 4 🔁 4 💬 1 📌 0
"The Hidden Power of Microorganisms: No microbes, no life…”

"The Hidden Power of Microorganisms: No microbes, no life…”

“Self-portrait of Saccharomyces Cerevisiae.”

“Self-portrait of Saccharomyces Cerevisiae.”

“Circles of Life: Microbes in Motion.”

“Circles of Life: Microbes in Motion.”

The 2025 Agar Art Contest winners have been selected! This year’s theme, “Microbes Make the World Go Round,” inspired 557 global entries—from food fermentation to antibiotic production. See the masterpieces and finalists! asm.org/press-releas... #agarart

15.12.2025 16:59 👍 82 🔁 37 💬 3 📌 5

@smartalyk.bsky.social

14.12.2025 13:36 👍 0 🔁 0 💬 0 📌 0

I’ll text you!

10.12.2025 01:22 👍 1 🔁 0 💬 0 📌 0

@acharlesorszag.bsky.social
@archaeon-alex.bsky.social
@anaerobicemily.bsky.social
@geosantiagom.bsky.social

To call out a few archaea enthusiasts :)

This seems like a cool archaea science communication/art moment we could help contribute to!

09.12.2025 21:51 👍 4 🔁 1 💬 2 📌 0

@archaeabio.bsky.social can maybe help here?

09.12.2025 13:48 👍 2 🔁 0 💬 1 📌 0
Post image Post image

The latest and most detailed review on a fundamental biochemical pathway: #glycolysis
#microbiology #biochemistry
onlinelibrary.wiley.com/doi/full/10....

07.12.2025 11:00 👍 9 🔁 4 💬 1 📌 0
Post image

In a manuscript on BioRxiv, we describe experiments exploring the culturome of the gut of adults with CF and in health, revealing an interesting redistribution of the microbes in the lumen vs. mucosa. The study is led by Sarvesh Surve a PhD student in my lab.
www.biorxiv.org/content/10.1...

03.12.2025 17:21 👍 10 🔁 4 💬 1 📌 0

Serendipity!

04.12.2025 02:02 👍 1 🔁 0 💬 0 📌 0

Love it! Also fun that you chose blue. They produce a coenzyme that makes them blue under UV!

03.12.2025 12:18 👍 2 🔁 0 💬 1 📌 0
Preview
Rare Phyla, Such as CPR and DPANN, Shape Ecosystem-Level Microbial Community Structure Dissimilarities - Microbial Ecology Rare microbial lineages, such as members of the candidate phyla radiation (CPR) bacteria and Diapherotrites, Parvarchaeota, Aenigmarchaeota, Nanoarchaeota, and Nanohaloarchaeota (DPANN) archaea, are i...

Rare Phyla, Such as CPR and DPANN, Shape Ecosystem-Level Microbial Community Structure Dissimilarities link.springer.com/article/10.1... #jcampubs

01.12.2025 14:34 👍 7 🔁 2 💬 0 📌 1

Guess you gotta come up for a visit!!!

26.11.2025 12:54 👍 1 🔁 0 💬 0 📌 0
Post image

When life gives you lab electrical shutdowns for maintenance … you make the most of the first bits of east coast snow!

26.11.2025 01:44 👍 3 🔁 0 💬 1 📌 0
Preview
BarTn7: Optimizing Bacterial Lineage Tracking at Sub-Species Resolution for Population Dynamics in Ecological and Evolutionary Studies Communities of bacteria undergo population bottlenecks which are crucial to their population, ecological, and evolutionary dynamics. However, conventional amplicon sequencing cannot distinguish such d...

Very excited to share a big part of my dissertation work with the Deutschbauer lab at LBNL and @ucberkeleyofficial.bsky.social! BarTn7: A method for bacterial lineage tracking at sub-species resolution in population, ecological, and evolutionary experiments.
www.biorxiv.org/content/10.1...

25.11.2025 22:38 👍 18 🔁 12 💬 2 📌 1
Post image

Excited to share new work from Sarvesh Surve examining the gut microbiota of adults with CF using colonoscopy samples and a culturomics approach. We note continued depletion of Bacteroidota (which we noted in kids) & enrichment of aerobes in the mucosa of pwCF.
pubmed.ncbi.nlm.nih.gov/41256617/

21.11.2025 15:09 👍 14 🔁 7 💬 1 📌 0

You know I love me some sulfidic air

25.11.2025 00:22 👍 0 🔁 0 💬 0 📌 0

It… set off the CO detector on my fire alarm 😂😂😂

25.11.2025 00:20 👍 0 🔁 0 💬 2 📌 0

I had to restart mine. Woods Hole mud was too sulfidic to keep in my apartment 😂

24.11.2025 23:38 👍 0 🔁 0 💬 1 📌 0
Post image Post image Post image Post image

DAY 168
SPECIES 168 - Prevotella intermedia
STAGE: Bacteria
MEDIUM: Arches Paper. Chromatek & HWC Watercolor. Sakura pen

Thanks to @lesliedaymicro.bsky.social for suggesting it!

#sciart #watercolor #bacteria #painting #art #paint

20.11.2025 07:34 👍 32 🔁 3 💬 1 📌 0
List of available cultures

List of available cultures

Ecoli cells (Dapi, on left) expressing bacterial (center) and archaeal 16S rRNA.

Ecoli cells (Dapi, on left) expressing bacterial (center) and archaeal 16S rRNA.

Clone-FISH paper out: Manuscript/resource alert #microsky 🦠 We present a collection of 30 E. coli (CloneFISH) cultures, each carrying a plasmid for the heterologous expression of a (near) full-length 16S rRNA gene from one of 30 lineages of archaea, including 17 yet uncultured ones.

17.11.2025 14:36 👍 45 🔁 18 💬 5 📌 3
Preview
One-pot production of colored bacterial cellulose Zhou et al. report the one-pot production of colored bacterial cellulose (BC) as a sustainable alternative to petroleum-based fabrics. Metabolic engineering enhanced colorant yields, while co-culture ...

Science is awesome ... www.cell.com/trends/biote... #violacein #pigments

16.11.2025 05:04 👍 53 🔁 14 💬 1 📌 3