Not AI, or maybe it is β¦ - at minimum a new way to explore symptoms π
Not AI, or maybe it is β¦ - at minimum a new way to explore symptoms π
βPlasma measures of p-tau217 can accurately identify individuals in the preclinical stage of Alzheimer disease where interventions are likely to have the most benefit in delaying or stopping disease progression.β
An implant that cures blindness, fantastic news for AMD patients! This could bring bionic sight within reach.
'The Pitt' Has Inspired More Organ Donation and End-of-Life Planning | Michael Schneider for Variety (@Variety)
https://variety.com/2025/tv/news/the-pitt-organ-donation-end-of-life-planning-study-1236562186/
A landmark moment for palliative care research! Discover the long journey that led to this breakthrough and why it matters for patients and clinicians. Read the full blog here: https://ow.ly/k31F50XkpUv
Selection bias could be the cause. But artificial sweeteners trigger insulin: A) Short term they move sugar into non-brain cells, causing relative brain hypoglycemia. B) Long term they drive insulin resistance, with or without meeting diabetes criteria, but cognitive decline expected.
Like much of human nature, itβs a question of trust - just like when elevators first switched from human operators to automation. People were skeptical, even afraid. Now, no one asks for a lift operator.
Robotic surgery outperforms laparoscopic in rectal cancer. Next step: train robots using AI like that in self-driving cars and humanoids. How long before an AI-driven robot beats the surgeon-controlled one?
Excess death in US compared to other high-income countries. This trend can probably only be broken by the Ozempic-pandemicπ€ and maybe some sensible healthcare reformsπ‘.
Superhuman performance of a large language model on the reasoning tasks of a physician.
arxiv.org/abs/2412.10849
Hospitalized patients with dementia are infrequently present in GOC conversations and less likely to have their values and preferences for medical care documented within a GOC note. #geriatrics #palliativecare agsjournals.onlinelibrary.wiley.com/doi/10.1111/...
Human(?) development is about to jump to hyperspace. With small tweaks, this could be applied to everything from scientific research to factory floors and logistics.
A graph showing the adjusted population-attributable fraction of obesity classes for prevalent health conditions
βOur study demonstrated associations between obesity, particularly severe obesity, and the incidence of 16 common health outcomes.β π Read the full study results by Z. Yao et al. in NEJM Evidence: eviden.cc/4iIRjGg
#MedSky #EndoSky
KDIGO heat map for CKD classification.
Heart and Kidney disease are related. Many patients have both, leading to CKM syndrome. http://spr.ly/6048uP0fo
As many as 9 in 10 adults with CKD don't know they have it. Kidney disease usually has 0 symptoms, & many people donβt know they have it until itβs very advanced.
Symptom support, unbiased and pure. Taking on the toughest cases: elderly patients. Get diagnoses and suggested investigations. Powered by our own AI (not Big Tech), but we use LLM as a sidekick. Easy, no login, free to use: Oired.com
The New England Journal of Medicine Extended Reduced-Dose Apixaban for Cancer-Associated VTE A Research Summary based on MahΓ© I et al. | 10.1056/NEJMoa2416112 | Published on March 29, 2025 Visual representations of the patients in the trial and the treatments they were assigned. Read the full Research Summary at NEJM.org.
In the API-CAT trial involving patients with active cancer and venous thromboembolism, extended anticoagulation with reduced-dose apixaban was noninferior to full-dose apixaban for preventing recurrent thromboembolic events. Full trial results and Research Summary: nej.md/41YkRZK
#MedSky
In Type 2 Diabetes SLGT2 decreased risk of Alzheimer with 43% and GLP-1 with 33% compared with other DM2 medications. No significant difference between SLGT2 and GLP-1.
jamanetwork.com/journals/jam...
Read, learn, think and challenge yourself should be added throughout life.
Zoster vaccine reduced the probability of a new dementia diagnosis by approximately 20% over a seven-year follow-up period.
βOn average, each dollar spent on vaccination yields a hefty $54 in returns.β - That is a good investment!
NEJM: Global Effect of Cardiovascular Risk Factors on Lifetime Estimates. With all 5 risk factors (high blood pressure, high cholesterol, diabetes, smoking, and unhealthy body weight) at age 50 lifetime cardiovascular disease risk was 38% in men and 24% in women.
www.nejm.org/doi/full/10....
Treating coronary artery disease risk factors early could make it a rare disease. But are we ready to take pills to prevent a disease that might occur 40 years later? Of course, a middle way already exists in clinical practice. However, this Lancet Commission rightly highlights prevention.
About to retire, prepare yourself or risk cognitive decline.
The number of geriatricians is shrinking, just 7,400 in 2022, down from 10,000 in 2000, while the aging population keeps growing. The American Geriatrics Society says weβll need 30,000 by 2030. The math isnβt adding up!
graph of NIH basisfor new drugs
A pie graph worth keeping in mind as the NIH budget plummets jamanetwork.com/journals/jam... for 356 new FDA drugs approved
"Kindness is like snowβit beautifies everything it covers." ~ Khalil Gibran
#Kindness cannot prevent, slow or cure #Alzheimers. But the presence or absence of kindness fundamentally changes quality of life for people experiencing #dementia and those who are #caregiving.
#quote
Or could the relative decline in dementia be partly due to the increasing use of smartphones among older people? A constant flow of information and interactions, which stimulate thought and keep the brain active, proven by how hard it is to get someoneβs attention when theyβre on their phone.
Gene repair inside the human body is now a reality.