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Dan Brierley

@drdanbrierley

Gut-Brain Neuroscientist (mostly focused on the brain end) | Wellcome Trust Sir Henry Dale Fellow | Group leader of UCL Gut-Brain Neurophysiology & Ingestive Behaviour lab | http://brierley-lab.org

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17.11.2023
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Latest posts by Dan Brierley @drdanbrierley

Come join us to build great open source tools for neuroscience!

Happy to answer any questions. If ephys and behaviour isn't your thing, we will have some imaging focussed RSE jobs soon!

05.03.2026 15:47 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Do you want to learn essential GIBA concepts and techniques?

We're hosting three mornings of expert-led sessions on gut, immune and brain research, from 23-26 March πŸ“’πŸŒŸ

πŸ†“ Open to all across the GIBA Network
πŸ“… Register by 13 March!

πŸ”— giba-uk.org/events/the-g...

04.03.2026 12:25 πŸ‘ 2 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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The molecular basis of force selectivity by PIEZO2 Nature - PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.

New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function.
www.nature.com/articles/s41...

04.03.2026 17:19 πŸ‘ 125 πŸ” 37 πŸ’¬ 2 πŸ“Œ 2
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Are you an undergrad student or know an undergrad who would thrive from a vacation lab project? πŸ”¬

Get up to Β£3000 financial support for a student undertaking a vacation laboratory project.

Deadline 27 February 2026

Apply: www.neuroendo.org.uk...

19.02.2026 17:31 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Assistant Professor within the Faculty of Medicine (20 Positions) at Imperial College London Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

20 posts available for non-clinical
Assistant Profs at Imperial
College London. Come work at @imppsych.bsky.social @imperialbrains.bsky.social. Collaborate in fields of eating & addictive behaviours, neuroimaging, gut-brain, emotional regulation etc. Deadline 11/3/2026
www.jobs.ac.uk/job/DQK133/a...

18.02.2026 21:05 πŸ‘ 5 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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GLP-1 (glucagon-like peptide 1) protects the mouse heart after ischaemia by activating ATP-sensitive K+ channels on pericytes that constrict coronary capillaries www.nature.com/articles/s41...

15.02.2026 12:40 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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'Hidden' group of gut bacteria may be essential to good health Scientists have pinpointed a group of bacteria that consistently appear in high numbers in healthy people, suggesting that these could one day be targeted through diet or probiotics

πŸ”¬ New insights from gut-immune-brain research 🌟

A study with our network's @alexmsalmeida.bsky.social uncovers a "hidden” gut bacterial group found in higher levels in healthy people.

Could this be key to microbiome health and future probiotic innovation? 🌍🦠
www.newscientist.com/article/2514...

12.02.2026 16:01 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Today, UCL turns 200. πŸŽ‰ For two centuries, our community has opened doors, challenged convention and pushed the boundaries of knowledge across every discipline. Thank you to everyone who’s been part of the UCL story, here’s to the next century. ✨

#UCL200 #LoveUCL

11.02.2026 08:04 πŸ‘ 139 πŸ” 80 πŸ’¬ 3 πŸ“Œ 26
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BBC Radio 4 - The Hunger Game A series exploring the weight loss drug revolution. Presented by Professor Giles Yeo.

Starting on 9 Feb - BBC Radio 4's The Hunger Game is a 5 part series presented by Prof @gilesyeo.bsky.social from the @ims-mrl.bsky.social, exploring the GLP-1 weight loss drug revolution - their development, the latest research and the marketing strategy behind them.
www.bbc.co.uk/programmes/m...

04.02.2026 11:50 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
Qualtrics Survey | Qualtrics Experience Management The most powerful, simple and trusted way to gather experience data. Start your journey to experience management and try a free account today.

We're still running this survey w/the Center for MINDS investigating factors that produce tangible creative insights from psychedelics. We unfortunately received >10k responses from bots, so we're no longer providing payment, but your responses will help science!
tiny.cc/Psychedelics...

29.01.2026 17:51 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Some additional clarity (not remotely reassuring) regarding the omnishambolic attempts at restructuring at UKRI...

06.02.2026 11:50 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The pause of response mode funding will have a huge impact on ECRs who are not yet fellowship ready.When researchers leave academia they rarely return. Clarity on when RM will reopen is urgently needed & transitions to the new model need to avoid investment gaps that disproportionally affect ECRs

01.02.2026 18:31 πŸ‘ 19 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0

We need to be shouting about the effects of this on junior researchers from the roofs, writing to our MPs. We are risking a "missing generation" of researchers.

01.02.2026 09:41 πŸ‘ 21 πŸ” 19 πŸ’¬ 1 πŸ“Œ 2
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Targeting the gut's immune system could tackle early stages of Parkinson's New research reveals how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice led by scientists at the UK D...

New research has revealed how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice co-led by Dr @soyonhonglab.bsky.social & Dr Tim Bartels @ukdri.ac.uk @uclqsion.bsky.social @uclbrainscience.bsky.social

29.01.2026 11:26 πŸ‘ 19 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0
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GRANT EXTENSION!

BSN's #ICN2026 travel grant deadline has been extended to 10 February 2026.

Attend the congress in Japan with our travel grant covering:

πŸ’· Registration fee
πŸ’· Abstract submission fee
πŸ’· Up to Β£1k for travel

Apply by 10 Feb: www.neuroendo.org.uk...

29.01.2026 18:33 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Dear peers:

PLEASE add housing conditions of your animals to the methods. It MATTERS if you house 2 or 5 mice in a cage, if they smell other mice (sex), if it is cold or warm in the room, if you house and breed your WT and KO models together etc.

Thank you for your attention in this matter.

24.01.2026 10:35 πŸ‘ 19 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0

Turns out that if you use a broom to scratch yourself everyone thinks you're a weirdo but if a cow does it they end up in the cover of Current Biology

22.01.2026 14:33 πŸ‘ 160 πŸ” 13 πŸ’¬ 7 πŸ“Œ 0
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Identification of Or5v1/Olfr110 as an oxylipin receptor and anti-obesity target Or5v1/Olfr110, a high-affinity odor receptor, detects an oxylipin signal to boost liver fat burning and glucose control, and a synthetic agonist can amplify this metabolic benefit.

Wow!
www.cell.com/cell/abstrac...

22.01.2026 16:54 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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UKRI pauses several funding calls amid priorities shake-up - Research Professional News β€œPeriod of transition” at funding agency sees some Medical Research Council funding opportunities on hiatus

Shift the govt wants at UKRI - and its new CEO wants - already in evidence as it pauses some funding calls.

UKRI says it is in a "period of transition" after spending review, as it aligns more funding to "national priorities" and economic growth.

www.researchprofessionalnews.com/rr-news-uk-r...

20.01.2026 10:55 πŸ‘ 2 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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Found an interesting conference abroad you’d love to attend but aren’t sure how to finance?

Get up to Β£1000 towards your travel costs with our International Conference Travel Grant.

Deadline 30.1.26

More info & how to apply: www.neuroendo.org.uk...

20.01.2026 13:58 πŸ‘ 1 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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UK supermarkets go all out for β€˜Jab-uary’ with food for those on weight-loss drugs M&S, Morrisons and Ocado among retailers bringing out ranges targeting shoppers taking Wegovy or similar

Shifting winds in the food sector in response to wide-spread use of weight-loss drugs #obesityisnotachoice www.theguardian.com/business/202...

17.01.2026 15:44 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
Lectureship in Psychology:Whiteknights Reading UK The closing date for applications is 23.59 on 27th February 2026

We are looking for an excellent #ECR to join our academic team as Lecturer / Assistant Prof.
Multimodal imaging, neurostimulation, and interests linking physiology and cognition are great fits, as are cognitive and affective neuroscience, including in development.
jobs.reading.ac.uk/Job/JobDetai...

16.01.2026 19:32 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Exciting times here at UCL!

14.01.2026 19:27 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

GLP-1 agonists (eg Ozempic) are showing promise to reduce alcohol drinking and perhaps opioid use. This is, of course, a potential therapeutic success which arises from the random walking of science, not an β€œefficient” directed research program.

13.01.2026 15:07 πŸ‘ 110 πŸ” 23 πŸ’¬ 4 πŸ“Œ 1

Beautiful paper! Somebody should do it in then viscerosensory brainstem.

08.01.2026 21:43 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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What can the Brain Knowledge Platform do for you? πŸ§ πŸ“ˆ

Join us on Jan. 14, 11am-12pm PT for a webinar on the new features and data in world's most comprehensive brain cell atlas.

πŸ”— https://alleninstitute-org.zoom.us/webinar/register/WN_Le5E4CXGSA2clMJ2VesyBw#/registration

05.01.2026 21:14 πŸ‘ 16 πŸ” 14 πŸ’¬ 1 πŸ“Œ 0

Happy New Year folks! πŸŽ‰

What are you looking forward to in your neuroendocrine research this year?

πŸ’¬ Let us know in the comments & we'll share how the BSN can support you in your work.

06.01.2026 12:20 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

We need to establish an acceptable proper timeline for the late 20th/early 21st C.

* 'Last year' = 2023-2025
* 'A couple of years ago' = after Lockdown
* 'A few years ago' = between 2004 and Lockdown
* 'About ten years ago' = 1994-2014

05.01.2026 14:11 πŸ‘ 146 πŸ” 31 πŸ’¬ 6 πŸ“Œ 4

2025 was the year we stopped debating whether paying peer reviewers might work and started showing that it does.

31.12.2025 22:13 πŸ‘ 20 πŸ” 9 πŸ’¬ 3 πŸ“Œ 0
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The expanding landscape of GLP-1 medicines - Nature Medicine This Review discusses the expansion of glucagon-like peptide-1 (GLP-1) medicines beyond type 2 diabetes and obesity, outlining opportunities for new indications, key questions around benefits and long...

2026 will bring waves of innovation to GLP-1 medicines from mechanisms to modalities to molecules delivery systems and new indications. #weightloss #obesity A glimpse of the.future here www.nature.com/articles/s41...

02.01.2026 10:12 πŸ‘ 12 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1