1/4 Thrilled to get this metagenomic diagnostic study over the line. We have an in house method that targets RNA viruses in respiratory samples, and evaluated this against 344 prospective samples tested by multiplex PCR.
www.medrxiv.org/content/10.6...
New preprint from us @modmedmicro.bsky.social where we validate the diagnostic accuracy of a metagenomic nanopore sequencing method for respiratory RNA viruses.
www.medrxiv.org/content/10.6...
Are you a post-doctoral microbiologist interested in characterising bacterial resistance evolution and want to apply your knowledge and expertise to developing new therapeutics for Klebsiella (and other Enterobacterales) infections? Then we need you! Apply now bit.ly/3MX39Ce close date March 13th 👀
Hoping to innovate community population-level AMR surveillance with the ALARUM team bmjopen.bmj.com/content/16/2.... Can we use metagenomics of pooled colonisation samples to predict clinical AMR burden & inform antimicrobial guidelines?
International Day of Women and Girls in Science 👩🔬
Proud to work alongside the scientists in our #microbiology lab whose work in antimicrobial resistance, public health and diagnostics has real-world impact!
#WomenInScience #AMR #PublicHealth @medsci.ox.ac.uk @ox.ac.uk @oxfordbrc.bsky.social
In this project, you’ll use lab experiments and a microplastics library to explore how bacteria grow and develop antimicrobial resistance in a hospital-like environment. Hands-on microbiology meets a real-world health challenge!
www.ox.ac.uk/admissions/g...
Life and medical sciences > CLINICAL 04
MMM has an exciting UNIQ+ project running this summer -apply now!
Bacteria, microplastics & resistance — what’s the connection?
#Microplastics are everywhere, even in hospitals. But what happens when bacteria stick to them? Come and find out!
@afswinkels.bsky.social @nstoesser.bsky.social
Happy our preprint is out🦠:
"Evaluation of an Oxford Nanopore sequencing workflow for mycobacteria from primary MGIT culture"
We developed and tested a workflow for long-read sequencing of #mycobacteria, including optimising DNA extraction and assessing how #ONT performs compared with #Illumina.
Our project "Sardinia’s Invisible Marine Microbiome" is one of six 2026 #PartArt4OW participatory art initiatives! Excited to do this with the brilliant @annadumitriu.bsky.social (image credit), Sardinian scientists, citizens of Alghero, and colleagues in @modmedmicro.bsky.social @bashthebug.net
Delighted to be involved in the Gram-Negative Antibiotic Discovery Innovator (Gr-ADI) consortium novonordiskfonden.dk/en/news/new-... as part of a project led by Annette von Delft gcgh.grandchallenges.org/grant/discov... @modmedmicro.bsky.social @samlipworth.bsky.social @philipwfowler.bsky.social
Univ of Oxford UNIQ+ scheme applications open: 7-week research internship this Summer www.ox.ac.uk/admissions/g.... Lots of projects - one in our lab on microplastics & AMR & hospital environments at @modmedmicro.bsky.social led by Aram Swinkels www.ox.ac.uk/admissions/g... (Clin Med 04). Join us!
🔬 New blog post!
Infections after joint replacement are serious, and identifying the bacteria quickly is crucial for patient care. We explain our research into metagenomic sequencing—reading all DNA in a sample to identify bacteria without needing lab growth.
👉 tinyurl.com/mrh8ukha
#AMR #Genomics
Our paper is out in Microbial Genomics! 🧬
We evaluate gnomonicus, an open-source AMR prediction tool, using 2,663 Mycobacterium tuberculosis genomes—showing how WGS can deliver faster, scalable TB resistance predictions.
Read the full paper here🔗 bit.ly/4iZepd1
#TB #AMR #Genomics
📢Job Alert! Translational Research Collaboration Manager in Infectious Disease and Antimicrobial resistance. 🦠💊 Know anyone who would be good? Pass it on! www.imperial.ac.uk/jobs/search-...
Our team wore blue for World Antimicrobial Awareness Week 2025💙
Research into how resistance emerges, spreads and can be prevented is vital. Our group works to understand these processes and develop better tools to detect, monitor and combat antimicrobial resistance.
#WAAW @oxfordbrc.bsky.social
This World Antimicrobial Resistance Awareness Week #WAAW, we’re championing our microbiology and infection researchers whose work is benefiting patients and informing health care policy. Read: oxfordbrc.nihr.ac.uk/research-the...
@ox.ac.uk @ouhospitals.bsky.social @modmedmicro.bsky.social
An infographic stating that between now and 2050, 39.1 million people globally will die from infections attributed to antimicrobial resistance. This number is equivalent to over half the current UK population.
An infographic stating that taking your full course of antibiotics can help reduce antimicrobial resistance and save lives.
Why is antimicrobial awareness important?
Antimicrobial resistant infections are rising. In the next 25 years an estimated 39.1 million people globally will die from infections with antimicrobial resistance.
So what can you do to help? Something as simple as finishing your course of antibiotics!
These subpopulations also reveal whether resistance arose before or after infection. Our findings show why even small resistant groups matter—and how choosing the wrong antibiotic can help them take over. 💥
#TB #AMR #WAAW #WAAW2025 #AntibioticResistance @oxfordbrc.bsky.social
In our study, we investigated how often such resistant minority populations occur in clinical TB samples, focusing on rifampicin (RIF). Including these minorities in resistance profiles significantly improved detection sensitivity. 🧪🔍
Resistance testing often yields a single profile per infection. If most bacteria appear susceptible, the antibiotic is used. But this approach fails when a minority, even as little as 5%, are resistant. Those few can survive treatment and take over the infection. ⚔️
For #WorldAntimicrobialAwarenessWeek, we introduce our recent paper on antibiotic-resistant subpopulations in TB.
TB may be one of humanity’s oldest diseases, yet it still kills over 1M people yearly. As resistance spreads, knowing each patient’s resistance profile before treatment is vital. 🧬💊
Antimicrobial resistance occurs when bacteria, viruses, fungi & parasites change over time - leading to medicines being less effective against them.
Here you see bacteria growing and antibiotics (the small discs) which kill the bacteria...unless they are resistant!
#WAAW #AMR @oxfordbrc.bsky.social
Are you interested in infections, the micro-organisms that cause them and antimicrobial resistance? So are @bashthebug.net and they're looking for new members to join their patient & public group. More info: bashthebug.net/lay-represen... Deadline 27 Nov @ouhospitals.bsky.social @medsci.ox.ac.uk
New paper by @vbrunner.bsky.social looking at detecting rifampicin resistant subpopulations in M. tuberculosis infections using genetics and putting a lower limit on the proportion that arose due to secondary infections.
bit.ly/47rwf42
@modmedmicro.bsky.social
@oxfordbrc.bsky.social
🔔🔔Post-doc in microbial genomics with @modmedmicro.bsky.social🧬 - deadline tomorrow! Big genomic and clinical datasets to play with, friendly and very multidisciplinary team!
my.corehr.com/pls/uoxrecru...
Our recent paper on rifampicin resistant subpopulations in M. tuberculosis (M. tb) has been published at JAC-antimicrobial resistance.
I am really happy to see this work published just hours before submitting my DPhil thesis! 🔗👇
doi.org/10.1093/jaca...
We have a fully funded PhD studentship available @modmedmicro.bsky.social in Oxford to work on a really cool project looking at population heterogeneity in bloodstream infections www.ndm.ox.ac.uk/study/dphil-... Please spread the word/get in touch if you'd like to chat.
