Congratulations Joanne!
Congratulations Joanne!
It is. I saw the pizza you posted earlier this week and immediately ordered a large pizza that I have been rationing all week. Last piece will be eaten today ๐
Second session at #CFM_MetCanc on the relationship between exercise, nutritional signals and cancer prevention.
Speakers:ย
Mark Febbraio,ย @monashuniversity.bsky.socialย
Gina DeNicola @ginadenicola.bsky.social,ย Moffit Cancer Center
โ๏ธ bit.ly/45jaORuย
Sponsored by @caixaresearch.bsky.social
Very helpful methods and protocol! www.sciexplor.com/articles/fos...
Great work @ginadenicola.bsky.social and team!
Excited to announce that registration is officially open for #METPHYS2026!
All meeting details can be found here:
www.sablesys.com/metphys-the-...
A practical, anesthesia-free platform for in vivo metabolic tracing! Preprint: doi.org/10.64898/202.... Questions? Reach outโhappy to share protocols!
Key advantages: โ Minimal anesthesia โ Physiological metabolite pools โ Mice move freely โ No surgical expertise needed โ Steady-state labeling comparable to jugular infusion.
Using UยนยณCโ-cystine infusion, we show tail vein achieves robust steady-state labeling of cystine and downstream metabolites (glutathione, taurine pathways) without the supraphysiologic tracer accumulation seen with jugular infusion.
A schematic depicting the tail vein catheter procedure.
Our solution is a tail vein catheter that can be implanted in just 5-10 min under brief anesthesia (vs 30-40 min jugular surgery). We secure the catheter and thread the tubing subcutaneously into a harness system. Mice can be infused awake. No surgery, no recovery, no analgesics needed!
A volcano plot showing metabolic changes in serum of mice exposed to isofluorane anesthesia compared to control conditions.
YES! Just 2 hours of isoflurane profoundly altered metabolism. Glycolysis/TCA โ, sulfur amino acids โ, acylcarnitines โ, while BCAAs โ, ketones โ, fatty acids โโsuggesting complex metabolic deregulation. These pool size changes compromise flux interpretation.
This project started when our jugular surgeon left research. After initial panic, we wondered โcan we use the tail vein?โ But we would need anesthesia, is it really that bad for metabolism?
Interested in stable isotope infusions but daunted by jugular catheter surgery? New from postdoc @kimyumi0201.bsky.social: our simple tail vein catheter method enables anesthesia-free infusions in awake, freely moving mice. ๐งต
Got up at 5AM today to do the Miles for Moffitt 10K with Basma from my lab. Success!
Exciting!
The best compliment ๐
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social
Job alert ๐ฃ Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in ๐ฑ and other organisms! DM me if you need more details!
jobs.ruhr-uni-bochum.de/jobposting/f...
My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social
A wonderful new opportunity - for both Rising Stars and established Research Leaders - to open a research lab in Ireland ๐ฎ๐ช๐งช
Up to 3.25 million euro in support ๐คฉ
#GlobalTalentIreland #Research #Ireland
Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/...
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social
Join us in at Moffitt! The Metabolism Program is recruiting at the Assistant Member (Assistant Professor) level. Review of applications starts September 1st. Please share! Details here: moffitt-cancer-center-careers.hctsportals.com/jobs/1883440...
Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Canโt wait for the next one! @olzmannlab.bsky.social
Hot science and hot temperatures at the FASEB Ferroptosis conference start tonight. Seriously the highs are 110F here ๐ฅต but it's beautiful!
To distract from your own stress responses (!!!), check out this awesome new study from the Commisso lab linking metabolic stress to regulation of the pancreatic tumor microenvironment! โจ
It's my first #newPI roll call on BlueSky! Calling all new #cancer PIs who just started or who are about to start their labs! Please say hi and what you work on so I can follow you if I don't already! ๐
IMPORTANT IMPORTANT IMPORTANT IMPORTANT
Please watch the workshop video and COMMENT by 5:00 Monday 7/14
This is the source of the "no more model organism only grants in NIH-funded research" decree.
New work from @karrethlab.bsky.social!
FRA1 drives melanoma metastasis through an actionable transcriptional network https://www.biorxiv.org/content/10.1101/2025.06.07.658418v1
Unravelling cysteine-deficiency-associated rapid weight loss
www.nature.com/articles/s41...