I am very excited to share this book! It has been so much to collaborate on the project. We hope you find it useful!
21.11.2025 22:11
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I am very excited to share this book! It has been so much to collaborate on the project. We hope you find it useful!
In an AJP editorial, @sophiedebs.bsky.social and @nataliematosin.bsky.social @sydney.edu.au discuss a study that unlocks the molecular secrets of the human habenula. bit.ly/3LyVicX
Fabulous job on this paper, check it out if you haven't yet.
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
New lab paper! @sophiedebs.bsky.social and @nataliematosin.bsky.social discuss a recent study from LIBD investigating the transcriptomic landscape of the human habenula in schizophrenia
🧠 Our editorial: psychiatryonline.org/doi/10.1176/...
📜 The original study: psychiatryonline.org/doi/10.1176/...
Thanks to BPA for receiving the work so well and all the positive feedback. The conference was a huge success, well done to Leigh and Alex and the LOC. Looking forward to the Australasian Neuroscience Alliance meeting in Sydney next year!
~dogfish
Home 💜
Well not most of the day, but try to get out of the house and down there daily!
I am very lucky to call this my backyard!
Our findings highlight astrocytes as crucial players in how exposure to severe adversity raises risk to psychopathology and position them as strategic pharmacological targets for future intervention strategies.
Read more here: www.biorxiv.org/content/10.1...
Human pluripotent stem cell-derived astrocytes from both two- and three-dimensional models confirmed that glutamate signalling is directly impacted by glucocorticoid activation.
Early-life adversity exposure produced more pronounced cellular changes than adversity experienced later in life, and female cases displayed stronger transcriptomic associations than males with adversity exposure.
In individuals with psychiatric disorders and high adversity exposure, we identified distinct alterations to glutamate-related synaptic functions, supported by histological quantification of >20,000 astrocytes.
We probed the diversity of ∼145,000 total human cortical astrocytes with single nucleus and spatial transcriptomics, and showed that human astrocytes comprise a molecularly and anatomically diverse cell population.
Latest lab preprint! Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear... so we dived in:
www.biorxiv.org/content/10.1...
Wonderful visits, highlighted the need for face-to-face interactions. Cant wait for all our upcoming collabs 🙌 thanks for carving time out to come see us @drcricru.bsky.social @nikosdaskalakis.bsky.social @rcbagot.bsky.social
The newspaper did say they reached out to you! I’m looking forward to reading your book, love your work 🩵
Microdosing delight to combat stress; interesting concept, backed by neuroscience. Was a pleasure to comment on the very excellent work of @drrachelbarr.bsky.social on how the experience of delight can tune down our stress response. @brainandmindcentre.bsky.social www.smh.com.au/lifestyle/he...
BIOLOGICAL STRESS
Figure 1. All-Cause Mortality Rates per 100 000 in the US vs OECD18 for <1-Year-Old Infants and 1- to 19-Year-Old Individuals, 2007-2022
US children's health has worsened from 2007 to 2023 across various indicators, including mortality, chronic conditions, and mental health.
ja.ma/4lZnRxG #MedSky #PedSky
This title!
“What happens to children’s mental health when we treat their parent’s depression? We have no idea. An empty systematic review.”
www.cambridge.org/core/journal...
Reminder that applications are due this week!
Note that we are only looking for candidates already in Australia for this position as we need to get started ASAP!
Looking for the next member of our team to support our ongoing projects. Check out the PD and if you think you're a fit, please apply!
This is important
A pleasure to spend the last week with @drcricru.bsky.social - to share her fascinating work on brain/placenta with my colleagues at @Sydney_Uni and introduce her to our beautiful city + home. So lucky to have had extended time to bounce ideas and ponder life with this brilliant mind✨
Check out our new paper led by the MINDS Lab original mass spec baddie @katrinazedmond.bsky.social 💃
Fabulous work led by our PhD student @katrinazedmond.bsky.social - and congrats on your first first-author paper, Katrina!