Heuer-Jungemann lab

Effects of DNA Origami‐Based Nanoagent Design on Apoptosis Induction in a Large 3D Cancer Spheroid Model The ability of DNA origami to penetrate through spheroid tissue and to induce cell death via the extrinsic apoptosis pathway is examined. Both structure of the DNA origami and the attachment of the a...

⚠️ New Paper Alert ⚠️
We showed that penetration of DNA origami structures 🧬 into cancer spheroids depends mostly on size, BUT, their ability to fully eradicate ALL viable cells in the tumoroid, depends on the way ligands are attached 😱 Wanna know more? --> onlinelibrary.wiley.com/doi/10.1002/...

Fully addressable designer superstructures assembled from one single modular DNA origami - Nature Communications Methods for creating large DNA assemblies with low cost and enhanced structural control are of interest. Here, the authors report moDON (modular DNA origami nanostructure) that combines two approaches...

📣NEW PAPER ALERT ⚠️

Finally out in Nature Communications, after unfortunately spending almost 1 year under review at Nature Materials 🤐
But very very pround of this work that was spearheaded by extremely talented PhD student Moritz Weck:
www.nature.com/articles/s41...

Most definitely 😁

Yesterday the very first PhD student from my group successfully defended her thesis 🤩
Congratulations Dr. Wassermann - I'm proud of you!
#proudPI

So helpful, thanks Elisa! Please add me to the list :)