The Le Group

Presenting PhD #1 from the Le Group: Dr. Dusty Cadwallader! (@dustyc94.bsky.social)

Many congratulations on a successful defense 🎉

Wishing you all the best as you begin your NSERC Postdoctoral Fellowship @chem.ubc.ca with Zac Hudson!

Once a semester our undergrads present a named reaction at group meeting to improve their skills in literature searching/comprehension.

Today, Emily was ambitious and gave us a stellar overview of the Catellani reaction! Got a review of the mechanism and some cool emerging applications 😎

Thanks for the inspiration (and the Fantastic talk! F-antastic! Get it?! #mechanismmonday #chemsky @christinemle.bsky.social

And yes, that is a full scale Dance Dance Revolution machine in my home.

Yesterday, @christinemle.bsky.social gathered current and former group members at her home to celebrate her recent tenure and promotion to associate professor! We were so busy having fun with Lola, the baby, DDR and all the familiar faces that we forgot to take a group photo 😅

Congrats Christine!!!

York University: NMR Specialist https://chempostingscanada.blogspot.com/2025/06/york-university-nmr-specialist.html

Final group talk today from Ali! #CSC2025 in Ottawa has been a blast and we’re all taking in the final poster night and preparing for the final day tomorrow. Till next year 🫡

Two more talks down from @maryamjabbarpoor.bsky.social and @dustyc94.bsky.social this morning in Ottawa!

Last talk from our group is tomorrow at 4 from Ali!

1 #CSC2025 talk down by @jesseleblanc.bsky.social who absolutely killed it (and had a line up of questioners after his section 👀)

Be sure to check out @maryamjabbarpoor.bsky.social and @dustyc94.bsky.social who are giving talks at 8 and 9am tomorrow morning!!!

Classic pre-CSC group photo (featuring new undergraduate volunteer Emily!!)

Carbamoyl #fluorides: an emerging frontier in organofluorine chemistry! Learn about their unique reactivity and potential in various fields.✨ Latest short review by Maryam Jabbarpoor and Christine Le
#fluorination

👉 buff.ly/lEEZIgF

Just under 1 week until #CSC2025 kicks off in Ottawa! Very excited to connect with the Canadian chemistry community. Be sure to come find our eager graduate students who will all be giving talks on their research!

It’s a live, laugh, love/hate relationship 😬

Also worth sharing that Sam started her pre-program summer research @uoft.bsky.social this week as she was accepted to their graduate program in chemistry! We’re very excited to see what she gets up to!!!

@leresearchgroup We are a research group in the Department of Chemistry at York University specializing in reaction and catalyst development for the synthesis of biologically relevant small molecules.

Keep up with group news on our website: www.leresearchgroup.com

- @dustyc94.bsky.social wins the NSERC PDF!!
- Sam wins the CSC silver medal for top chemistry GPA at York (3rd year in a row one of our undergrads has won this award 😎)
- @christinemle.bsky.social gave an invited talk at Spring ACS

An exciting week as our undergrads defended their CHEM4000 theses! Congrats Sam and Sepi!

Congrats to our rockstar undergrad Sam for winning best organic chemistry talk this weekend at #SOUSCC53!!!

Time is slowed by their eternal gaze

My (person of mystery) phone tells me that it’s been 2 years to the day since @jesseleblanc.bsky.social googley-eyesed our lab 👀😳

Hello, San Diego! I’ll be presenting at #ACSSpring2025 on Tuesday at 4:25 pm in the “Chemistry Across the Border 🇨🇦/🇺🇸” symposium. Please come by and say hi 👋

🚨Paper alert!🚨 Our review on the synthesis of carbamoyl fluorides and their use in fluoride-enabled reactions was just published in @synthesis1969.bsky.social! An excellent summary of an emerging field by @maryamjabbarpoor.bsky.social www.thieme-connect.com/products/ejo...

Carbofluorination of π‐Bonds and Related Reactions Involving Tandem C−C/C−F Bond Formation A review on the carbofluorination of π-bonds and related transformations involving tandem C−C/C−F bond forming reactions is presented. The application of electrophilic fluorine and nucleophilic fluor...

Some of our work features the carbofluorination of pi bonds, a strategy for rapidly increasing molecular complexity via fluorine incorporation. Ali and @dustyc94.bsky.social recently published a review on this topic. Check it out here #ICYMI! chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

Some cool work from our neighbours in the Baumgartner lab featuring some involved crystallography from our grad student @jesseleblanc.bsky.social ✨

Want to get to know us better? All of our talented graduate students will be attending #CSC2025!! Submit your abstract before tomorrow and come meet us and a ton of other amazing Canadian chemists!

BF3-Catalyzed Intramolecular Fluorocarbamoylation of Alkynes via Halide Recycling A BF3-catalyzed atom-economical fluorocarbamoylation reaction of alkyne-tethered carbamoyl fluorides is reported. The catalyst acts as both a fluoride source and Lewis acid activator, thereby enabling...

Here is some of our previous work on Lewis acid (pubs.acs.org/doi/10.1021/...), Lewis base (pubs.acs.org/doi/10.1021/...) and transition metal (pubs.rsc.org/en/content/a...) catalyzed reactions! (2/2)

BF3-Catalyzed Intramolecular Fluorocarbamoylation of Alkynes via Halide Recycling A BF3-catalyzed atom-economical fluorocarbamoylation reaction of alkyne-tethered carbamoyl fluorides is reported. The catalyst acts as both a fluoride source and Lewis acid activator, thereby enabling...

If you haven’t heard of us, we are a Canadian research group who work with fluorinated molecules 🤓 We love catalysis, and we don’t discriminate! (1/2)

Hello #chemsky!! We’re so happy to have successfully migrated! You may know us as the carbamoyl fluoride people, but we opened the new year with a report on acyl fluorides. Check it out an follow us for Le Lab updates 😎⚗️

@leresearchgroup.bsky.social there we are 😍
we're finally on Bluesky 🦋