Jenny Sachweh

Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...

Beautiful work, congratulations!

Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.

We extend our deepest condolences to his family, friends, and colleagues.

www.embl.org/news/people-...

Deep Learning for Microscopy Image Analysis Topics The following will be covered extensively during lectures, exercises, and project work: Image denoising and restoration (fully supervised and self-supervised) Image translation (e.g.,

🚨 Alarm!!! 🚨
AI/ML course for microscopy image analysis!!! 🧐
In 2026 at Janelia (@hhmijanelia.bsky.social), no tuition, housing and meals provided! Isn’t that borderline unbelievable?!?

20 students, ~14 TAs and lecturers
🗓️ June 4-18 2026

✍️ Jan 15 2026 ✍️

🔁 pls!!

www.janelia.org/you-janelia/...

Highly recommend this (literally life-changing) course at the MBL to anyone who wants to do the most amazing projects as part of an incredible group of scientists from diverse backgrounds, joined by their shared passion for moving cell biology forward! Check it out at the virtual open house!

Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

Congratulations, Julia Mahamid!

Julia Mahamid receives the @dfg.de Leibniz Prize for her work on structural cell biology!

#LeibnizPreis

CryoET of symbiotic cell-cell interfaces 🦑🦠
🔗 www.biorxiv.org/content/10.1...

Anthony A. Hyman will become EMBL’s next Director General.

He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999.

www.embl.org/news/people-...

Happy to see that our paper on NPC (a)symmetry inspired a newspaper article!

Special thanks to my examiners @becklab.bsky.social, @mixmue.bsky.social, @heilemannlab.bsky.social and Volker Dötsch for a fun discussion round that concluded it, and to the Beck lab for a great PhD hat!

Yesterday I finally defended my PhD thesis - time to say thank you to all those who were part of this journey as mentors, collaborators, colleagues and friends!

Great work of @deglushk.bsky.social from my PhD lab @mpibp.bsky.social on how to get more information out of all the membranes you see in cryoET data!

We are looking for motivated #postdocs to join the lab! Biochemistry/microbiology/cryo-EM experience? Excited by #cryo-EM/ET, #chromatin? ❄️🧬🧫
Interdisciplinary projects, top EMBL facilities!
Email CV + short cover letter → svetlana.dodonova@embl.de
Info about the group: www.embl.org/groups/dodon...

Congrats David!

Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...

Course Offerings | Marine Biological Laboratory

🔬 Applications are now open!

Join MBL’s world-renowned Advanced Research Training Courses, where scientists from around the globe come together to explore new ideas, master cutting-edge techniques, and become part of a dynamic network.

➡️Apply today: go.mbl.edu/courses

Figure 1 from the preprint

Check out our preprint! With new molecular mechanisms, 140 subtomogram averages, and ~600 annotated cells under different conditions, we @embl.org were able to describe bacterial populations with in-cell #cryoET. And there’s a surprise at the end 🕵️

www.biorxiv.org/content/10.1...
#teamtomo

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...

What could be more exciting than watching Euplotes scurry around under the microscope? How about adding some raptorial predation by supergiant cannibal cells?

www.biorxiv.org/content/10.1...

Video by Vittorio Boscaro.

1/n

If you are thinking about the future of structural biology, we are too! Our two cents (Jürgen Plitzko and I) just got published online here: authors.elsevier.com/sd/article/S...

Thanks :)

How many photons are in a GFP? — more than last year, and more than you thought. Here's a simple, cheap, and practical method to break a fundamental limit in fluorescence microscopy. But it only works in light sheet!

Thanks Carolin!!

Thanks Iskander!

Thanks Tamas! Hope you’re doing well!

Special thanks from my side also to @sonjawelsch.bsky.social who keeps the electron microscopy facility @mpibp.bsky.social running!

Thanks to everyone involved: Mandy Börmel, Sven Klumpe (@svenklumpe.bsky.social), Anja Becker, Reiya Taniguchi, Marta Kubańska, Verena Pintschovius, Eva Kaindl, Jürgen Plitzko, Florian Wilfling (@wilflinglab.bsky.social),
Martin Beck (@becklab.bsky.social) and Bernhard Hampölz!

The small GTPase Ran defines nuclear pore complex asymmetry Nuclear pore complexes (NPCs) bridge across the nuclear envelope and mediate nucleocytoplasmic exchange. They consist of hundreds of nucleoporin build…

My PhD paper is in press @cellpress.bsky.social and now online: www.sciencedirect.com/science/arti...!

Contents: weird #NPCs in yeast and flies, #CLEM, in situ #cryoET and more!

Made possible by the amazing @becklab.bsky.social team at @mpibp.bsky.social and collaborators! #TeamTomo