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Vitor Lopes dos Santos

@vitorlds

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30.10.2023
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Latest posts by Vitor Lopes dos Santos @vitorlds

I’m building a foundational reading list for our lab (systems & circuit neuroscience, compneuro, modeling, neuromodulators, population coding etc.).

I’d like to crowdsource recommendations.

Which review(s) would you consider mandatory reading for the next generation of researchers?

01.03.2026 14:03 👍 67 🔁 23 💬 7 📌 2

A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe https://www.biorxiv.org/content/10.64898/2026.02.12.705512v1

14.02.2026 11:15 👍 3 🔁 2 💬 0 📌 1
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Adaptive communication between cell assemblies and “reader” neurons shapes flexible brain dynamics Cell assemblies have been proposed as key units of brain activity, underlying diverse functions, but their basic features are not well understood. This study shows that interactions between cell assem...

Cell assemblies are drawing increasing attention in neuroscience, but one could argue that they are just an epiphenomenon. Is the activity of cell assemblies relevant for the brain?
The short answer is yes. The long answer is in our paper, now online at PLOS Biology. 🧵👇 1/10
doi.org/10.1371/jour...

06.12.2025 21:26 👍 19 🔁 6 💬 2 📌 1
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Happy to announce the 2nd Hippocampus Green Meeting
📍 Barcelona, Spain
🗓️ May 11–12, 2026
Organized together with Manu Valero, Lisa Roux and Dan Bendor
🎤 Keynotes: Nachum Ulanovsky & György Buzsáki
‼️ Call for abstracts now open
🔗 hippocampusgreen.net/wp/
#HippocampusGreen

07.12.2025 11:51 👍 29 🔁 14 💬 0 📌 1
What Billionaire Tech CEOs Get Wrong About The Future, with Adam Becker
What Billionaire Tech CEOs Get Wrong About The Future, with Adam Becker YouTube video by StarTalk

youtu.be/o6UdRXloqGc?...

06.12.2025 18:05 👍 1 🔁 0 💬 0 📌 0

1) This is a great idea.

2) I would be happy to mentor a project like this. If you want to do a project eg at the intersection of Philosophy of Science and NeuroAI, please feel free to reach out to discuss, or just put my name as a suggested mentor!

23.11.2025 19:12 👍 20 🔁 2 💬 1 📌 0

Interested in doing a PhD on how #psychedelics (or other psychoactive substances) impact psychological or social processes @durhampsych.bsky.social ?

Have a look at the NINE DTP scheme, now open. DM me if interested.

19.11.2025 21:37 👍 6 🔁 10 💬 1 📌 0
Title page of our paper

Title page of our paper

***Publication alert***

"Pathological tau alters head direction signaling and induces spatial orientation"

www.cell.com/cell-reports...

21.11.2025 23:59 👍 16 🔁 4 💬 1 📌 0
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Thrilled to announce I'll be joining the Division of Neuroscience at @manchester.ac.uk as a Lecturer in Feb '26!

The DuLab will explore how the brain integrates sensory streams into internal maps 🌐 using the rodent head-direction circuit, the 'neural compass', as a starting point for the journey 🧭

20.10.2025 20:20 👍 65 🔁 4 💬 11 📌 3
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Spread the word! 🗣️🎙️
Together with @azulsilva.bsky.social and Bluesky-less Magdalena Miranda, supported by @elife.bsky.social, we’re organizing a webinar bringing together people working in science communication and outreach.

Please, feel free to share the flyer with anyone who might be interested!

15.10.2025 13:38 👍 8 🔁 8 💬 0 📌 0

This is beautiful work and quite the discovery. This also plays nicely with the idea that superficial place cells are rigid and deep are flexible. Seems to suggest that the flexibility is more about past rep's integrating with newer rep's, than the opposite.

02.10.2025 17:52 👍 5 🔁 1 💬 1 📌 0
An image of Jane Goodall and a chimpanzee, from 1965. Photo courtesy CBS Photo Archive / Getty.

An image of Jane Goodall and a chimpanzee, from 1965. Photo courtesy CBS Photo Archive / Getty.

The naturalist Jane Goodall died today at 91. Hope, she argued, is not merely “passive wishful thinking” but a “crucial survival trait.” Revisit a conversation with Goodall, from 2021: nyer.cm/F55JtsS

01.10.2025 22:05 👍 2530 🔁 639 💬 43 📌 47
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I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !

With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics

02.10.2025 15:46 👍 71 🔁 28 💬 4 📌 1
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Sosa Lab

The Sosa Lab website is now live!
www.sosaneurolab.com

We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.

22.09.2025 21:22 👍 92 🔁 37 💬 0 📌 0
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🚨 New preprint! 🚨

Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇

📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩

#neuroskyence

17.09.2025 19:32 👍 132 🔁 56 💬 10 📌 6

Proud to take on this challenge: building the new Centro de Neurociencias Cajal @institutocajal.bsky.social into a space where neuroscience crosses boundaries and transforms how we understand the 🧠!!

04.09.2025 16:39 👍 48 🔁 8 💬 11 📌 1

Going to open an escape room where hippocampus researchers have to solve riddles without using space as an explanation for everything

13.07.2025 18:44 👍 34 🔁 3 💬 4 📌 1
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Direct entorhinal control of CA1 temporal coding Nature Communications - Temporal coding in the hippocampus is thought to be key for memory and predictions. Here, the authors show that blocking one entorhinal input affects two aspects of...

Our collaboration - from PhD work - examining input-specific (EC L3) contributions to rate and temporal coding in CA1 place cells is now out in @natcomms.nature.com 🔬🧠

rdcu.be/evWtz

12.07.2025 17:09 👍 37 🔁 9 💬 7 📌 0

I know it’s popular to think of citations as attribution of credit, but a part of me also likes to think of them as a trail of fun breadcrumbs for someone 20 years in the future.

02.07.2025 20:36 👍 26 🔁 1 💬 0 📌 1
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Study visually captures hard truth: Walking home at night is not the same for women An eye-catching new BYU study shows just how different the experience of walking home at night is for women versus men.

this heat map study of gender differences of walking through urban environments at night is not surprising, but still sort of incredible to see

news.byu.edu/intellect/st...

23.06.2025 18:16 👍 182 🔁 53 💬 3 📌 12
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It's so heartbreaking to see one of the 'three angry old men'* flirting w the idea of bombing a country so nonchalantly.

Like 90million ppl are at the mercy of the 'noise' in his drift diffusion process--is it accumulating to this bound or that bound😞

*see this: www.theguardian.com/commentisfre...

18.06.2025 17:21 👍 4 🔁 1 💬 0 📌 0
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A flexible hippocampal population code for experience relative to reward - Nature Neuroscience Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵

www.nature.com/articles/s41...

12.06.2025 17:24 👍 128 🔁 40 💬 9 📌 0
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My latest Aronov lab paper is now published @Nature!

When a chickadee looks at a distant location, the same place cells activate as if it were actually there 👁️

The hippocampus encodes where the bird is looking, AND what it expects to see next -- enabling spatial reasoning from afar

bit.ly/3HvWSum

11.06.2025 22:24 👍 272 🔁 86 💬 10 📌 5

Thank you Sanja!

07.06.2025 19:20 👍 0 🔁 0 💬 0 📌 0
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The embedding enables a cool experiment: start with a tetrode in CA1 pyr, lower it gradually, and project the signal at each step.
The tetrode follows the predicted path, and the gamma profiles match the silicon probe data beautifully at each step.
See one going from CA1 pyr to DG midmol below!

06.06.2025 11:37 👍 1 🔁 0 💬 0 📌 0
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GitHub - vitorlds/Hipp-LFP-embedding: Code for Lopes-dos-Santos et al. (2025) Cell Reports Code for Lopes-dos-Santos et al. (2025) Cell Reports - vitorlds/Hipp-LFP-embedding

If you're interested in the code, see: github.com/vitorlds/Hip...
I’ll be updating it soon with a newer Python version and more data!

(13/13)

05.06.2025 17:08 👍 3 🔁 1 💬 0 📌 1

Overall, I had a lot of fun preparing this manuscript.
It started as a side project to support various experiments in the lab, but it grew into its own thing.
Huge thanks to Demi and David for working with me on this at @mrcbndu.ox.ac.uk, and to our reviewers for helping improve the paper.
(12/13)

05.06.2025 17:08 👍 3 🔁 1 💬 1 📌 0
Redirecting

In short: LFPs carry rich circuit information.
We mapped oscillations and neuronal firing across CA1–DG layers.
This opens new doors for identifying oscillations, circuit motifs, and homogenize layer identification across datasets.
Check out the paper: doi.org/10.1016/j.ce...

(11/13)

05.06.2025 17:08 👍 4 🔁 0 💬 1 📌 1
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Using optogenetics, we tested how CA1 interneurons across layers respond to upstream input.
CA3 terminal stimulation strongly activated pyramidale (PyrInt) and radiatum (rad) interneurons, while EC terminal stimulation strongly drove LM interneurons.

(10/13)

05.06.2025 17:08 👍 2 🔁 0 💬 1 📌 0