Leanne Iannucci

So excited and grateful to have been named a 2025 Leading Edge Fellow and for the opportunity to be a part of this amazing community!

UDS members enjoying the 14th International BMP conference in Philly 😁

Early epigenetic priming of regeneration studied with a novel transgenic epigenetic reporter Tissue regeneration requires previously differentiated cells to regain developmental plasticity. However, the upstream mechanisms initiating this process remain poorly understood. Here, we leverage a ...

@jimmykjm.bsky.social and @isabellaclsci.bsky.social et al. focus on epigenetic changes during fin regeneration in this preprint:

www.biorxiv.org/content/10.1...

congrats Miranda!!

So excited to share the first preprint of my postdoc work with @katwrog.bsky.social! 💡🐟

🐟💕😊

“Together, our results establish this optogenetic toolkit as a potent experimental platform to rapidly, directly, and adjustably activate FGF, BMP, and Nodal signaling in zebrafish embryos.”

New work from @leanneiannucci.bsky.social & @katwrog.bsky.social 🔥

Thanks for checking it out!!😊

Overexpression of enhanced yellow fluorescent protein fused with Channelrhodopsin‐2 causes contractile dysfunction in skeletal muscle Optogenetic tools like Channelrhodpsin-2 (ChR2) are useful for inducing skeletal muscle contraction using blue light. However, the prevalence of fluorescent proteins like EYFP may cause functional is...

I am thrilled to share our recent publication, led by recent PhD graduate Dr. Syeda Lamia + collab with @brianglancylab.bsky.social, on how overexpression of EYFP using optogenetic mouse strains leads to skeletal muscle contractile dysfunction. 🧵
faseb.onlinelibrary.wiley.com/doi/full/10....