Hannes Mutschler

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#OriginOfLife #Conference #Science

Membraneless protocell confined by a heat flow - Nature Physics In living cells, a complex mixture of biomolecules is assembled within and across membranes. This non-equilibrium state is maintained by sophisticated protein machinery, which imports food molecules, ...

PURE meets heat flows and likes what it finds!
Fantastic work by Alex & Noel from the Braun lab! Glad to have been part of it. @lmumuenchen.bsky.social
link.springer.com/article/10.1...
@crc392molevo.bsky.social
@tu-dortmund.bsky.social

Computational De Novo Design of Group II Introns Yields Highly Active Ribozymes Group II introns (G2Is) are large self-splicing ribozymes with emerging potential in biotechnological applications. Despite growing interest, their complexity has so far precluded efforts to design t...

Great work by @szokoli.bsky.social, who used RNA inverse folding to design functional Group II introns. One variant, Arq.I2, performs on par with natural ribozymes.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

From RNA-peptide coevolution to cellular life at heated air bubbles | BubbleLife | Projekt | Fact Sheet | HORIZON | CORDIS | European Commission "The origin of life on Earth is one of humanity's profound mysteries that lacks scientific answers. We aim to answer this fundamental question by performing pioneering experiments starting from the Da...

Interested in a #postdoc in #originsoflife research? Are you a geek who loves #RNA, #RNAseq and tinkering, with a background in #biochemistry, #chemistry or #biophysics? Join #bubblelife! Apply now by email (CV + a short motivation letter)!
cordis.europa.eu/project/id/1...