Yolanda Perez

🤯🤯🤯

I’m afraid to ask…

Será por eso Federica, será por eso 🥺

My husband and I went to Hawaii in 2008, and the flight from Barcelona cost around €1,000 per person. The different types of accommodation (a private bungalow, a hotel and a bed and breakfast) cost us between $100 and $140 per night. With current prices, we wouldn't even have considered going.

Applications and insights of NMR in enzyme engineering and biocatalysis In order to be used in biocatalysis, natural or de novo enzymes must be engineered to function under the desired reaction conditions. Rational enzyme design draws on experimental data such as struc...

New paper out❗️Our latest review article summarises the main current NMR approaches for studying enzymes and proposes new strategies to overcome existing limitations, thereby enabling a broader application of NMR in underutilized areas such as enzyme evolution and engineering.
#NMRchat #Biocatalysis

Not the kovsky.net Reference Resolver? 😄

A screenshot of the Bluesky app demonstrating how you can now tap the "Translate" button to translate a post without leaving the app.

v1.118 rolls out today!

New in this update: You can now translate posts without leaving the app.

Simply tap "translate" on mobile and your phone's built-in translation takes it from there.

Very happy to welcome the @sbesp.bsky.social Spanish Biophysical Society to Bluesky🥳, and very proud that the first post highlights our paper on the #ExHOS!

The registration for the next edition of the AMPERE NMR School is now officially open!

The next edition will take place June 14-20, 2026 in Zakopane, Poland

Check all the information at our website👇
School.web.amu.edu.pl

High-pH NMR to Identify Macromolecular Hydrogen-Bonds and Foldons https://www.biorxiv.org/content/10.64898/2026.02.28.708709v1

Lunes.

Magnetic resonance enthusiasts! 🧲
Save the date for the Global NMR Online Conference 🗓️ July 22-24, 2026! Fully online, 3 days of MR presentations & discussions (free & open to all! No travel, no fees, just science!)
Stay tuned for registration details! #GlobalNMROC2026 #NMR

To #NMR community. I have just learned of the death of Prof. (Emeritus) Jim Emsley of the Univ. of Southampton. This is very sad news.
He was among pionneers in anisotropic NMR (thermotropic LC).
Thanks to him, I learned a great deal during my postdoc studies (Oct 95-Oct 96).

No me canso de repetirlo 👇

"Los modelos de lenguaje no planifican; generan textos que parecen planes.

Los modelos de lenguaje no resuelven problemas; generan textos que parecen soluciones.

Los modelos de lenguaje no piensan; generan textos que parecen como si lo hicieran."

Andriy Burkov

Remembering Rob Schurko - MagLab MagLab’s NMR Director described as extraordinary leader, first-rate scholar, and remarkable person.

We are deeply saddened at the passing of Rob Schurko, director of the lab's NMR facility, FSU chemistry professor, brilliant scientist, colleague, mentor, and friend.
nationalmaglab.org/news-events/...

webinar poster

Monday, March 9, 11 am CET / 6 am EDT (note EDT time) AMPERE Off-Resonance Webinar @group-ampere.bsky.social Career Pathways in Magnetic Resonance, organized by the Young AMPERE Bureau www.linkedin.com/groups/13517... #NMRevents #NMRchat #NMR 🧲

This post is definitely a milestone for Merriam-Webster

My quote of the day

We all have our time machines. Some take us back, they're called memories. Some take us forward, they're called dreams.

Jeremy Irons

A detailed comparison of de novo designed proteins by NMR finally puts to rest the idea that structure prediction confidence metrics have any correlation with local flexibility

Dynamic signature of activity-stability tradeoff in lactamase evolution | Nature Communications Our ability to understand protein evolution hinges on understanding how evolutionary landscapes are shaped at the fundamental protein level. Using TEM-1 β-lactamase we show that molecular traits related to the statistical ensemble nature of protein structure contribute to broader substrate specificity, active site-scaffold communication, and the selection of stabilizing substitutions. During the evolution of cefotaxime resistance, the initial mutation reorganizes the active site, introducing a new function conformation. Secondary substitutions improve catalytic efficiency by redistributing the ensemble and restoring a significant population of the original conformation, rather than by stabilizing the new conformation. Stability defects associated with initial mutations are not evenly disseminated but are clustered at specific distal scaffold elements. The capacity of mutants to independently modulate the populations of individual active site walls and scaffold regions through narrow re

Explore how TEM-1 β-lactamase evolution reveals protein landscape intricacies! Initial mutations boost cefotaxime resistance by active site reorganization. PMID:41559101, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-68620-z #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

AlphaFold Database welcomes community datasets Latest AlphaFold Database update adds high-value datasets for microbial and viral proteins, generated by specialist communities

Delighted to see over 17 million new protein structure predictions from novel proteins in AllTheBacteria are now integrated into the AlphaFold Database at @ebi.embl.org !
Huge work from @gbouras13.bsky.social @oschwengers.bsky.social and friends to generate these.

www.ebi.ac.uk/about/news/u...

Large-scale exploration of protein space by automated NMR https://www.biorxiv.org/content/10.64898/2026.02.16.706194v1

The same thing has happened to me recently. I requested a major revision (in the analysis of the NMR data certain things were taken for granted that were not experimentally supported), and when I received the revised draft and didn’t reply inmediately, I was told that my review was no longer needed.

Automated Chemical Profiling of Wine by Solution NMR Spectroscopy: A Demonstration for Outreach and Education Profiling complex chemical mixtures provides a unique opportunity for outreach and education. Here, we develop a teaching module using one-dimensional 1H nuclear magnetic resonance (NMR) spectroscopy ...

ACS Journal of Chemical Education (open) Automated Chemical Profiling of Wine by Solution NMR: A Demonstration for Outreach and Education, Lily Capeci, Ruoqing Jia, Mary E. Peek, Miriam K. Simma, Elizabeth A. Corbin, F.N.U. Vidya, Hongwei Wu*, Johannes E. Leisen*, Andrew C. McShan* #NMRchat 🧲

Pleased to share the final version of this behemoth of a paper, now finally published. I guess I can retire now?
www.nature.com/articles/s41...

More functional data, many thousands of words removed, and a few other updates from last year's preprint.

Two puppeteers. One is shocked and looks distraught. The other one is smiling happily. It has been reshaped into a heart and is saying “happy valentine’s day baby”. There is a blue flames Bunsen burner in the background

Happy Valentines Day

#chemsky #chemchat

You can't... repeal... a scientific finding. At that point it's just called lying about it.

Point of no return: a hellish ‘hothouse Earth’ getting closer, scientists say Continued global heating could set irreversible course by triggering climate tipping points, but most people unaware

The only biosphere in the known universe capable of supporting human life is being turned into a hell planet because most of Earth's governments refuse to stop trying to satisfy the insatiable greed of a plutocracy composed of people who already have more money than they could spend in 20 lifetimes.

Vista de Erlenmeyer y su matraz | Anales de Química de la RSEQ

📙Imágenes de la Química | Erlenmeyer y su matraz #Analesdequímica
✍️Santiago Álvarez
➡️

Today I learned that E. coli are pressurized. The cells are roughly pressurized to the same level as a car tire.

I really love working with my microbio colleagues. These little bugs are so neat.