Mariano Alvarez

Years ago I remember reading a review paper that compared Breeder's Equation forecasts of evolutionary change, against observed changes, to evaluate accuracy of quantitative genetic predictions of selection response. I can't find it now... anyone know of a good comparison along these lines?

Improving the cotton simulation model, GOSSYM, for soil, photosynthesis, and transpiration processes GOSSYM, a mechanistic, process-level cotton crop simulation model, has a two-dimensional (2D) gridded soil model called Rhizos that simulates the below-ground processes daily. Water movement is based...

Improving the cotton simulation model, GOSSYM, for soil, photosynthesis, and transpiration processes - Scientific Reports

A scalable method for modulating plant gene expression using a multispecies genomic model and protoplast-based massively parallel reporter assay Precision breeding tools such as CRISPR-Cas genome editing can speed up innovation in plant biotechnology and boost crop yields. The challenge remains to efficiently apply precision breeding methods to...

A scalable method for modulating plant gene expression using a multispecies genomic model and protoplast-based massively parallel reporter assay | bioRxiv

Model-X knockoffs reveal data-dependent limits on regulatory network identification

The near-complete genome assembly of hexaploid wild oat reveals its genome evolution and divergence with cultivated oats The near-complete genome of hexaploid wild oat, along with 117 global wild and cultivated accessions, reveals genome divergence between wild and cultivated oats and a large fragment duplication event...

The near-complete genome assembly of hexaploid wild oat reveals its genome evolution and divergence with cultivated oats

A meiotic driver hijacks an epigenetic reader to disrupt mitosis in noncarrier offspring

Developmental Plasticity-Inspired Adaptive Pruning for Deep Spiking and Artificial Neural Networks Developmental plasticity plays a prominent role in shaping the brain’s structure during ongoing learning in response to dynamically changing environments. However, the existing network compression methods...

Developmental Plasticity-Inspired Adaptive Pruning for Deep Spiking and Artificial Neural Networks

This startup is using AI to ‘supercharge’ crop breeding. It could help protect farmers from the climate crisis | CNN Avalo, a crop development company based in North Carolina, is using machine learning models to accelerate the creation of new and resilient crop varieties.

Hey we’re in the news! www.cnn.com/climate/ai-c...

Genetic Discrimination Is Coming for Us All Insurers are refusing to cover Americans whose DNA reveals health risks. It’s perfectly legal.

Not everyone has a genetic disease but everyone has a polygenic risk score www.theatlantic.com/health/archi...

We're hiring a breeding specialist at Avalo! We're looking for someone who is comfortable leading a team, passionate about the future of crop breeding, and thinks creatively about the use of technology in the crop development process. t.co/iEQIpTzNGP

Happy to see this out! @brandonlind.bsky.social tested genomic maladaptation (offset) estimates with common garden data for 2 conifers. Climate adaptation candidate loci were no better than random loci. Populations included in model building matter. onlinelibrary.wiley.com/doi/10.1111/...

About 50% of the improved yield from crops has come from genetics and half from agronomy in the last 75 years. This nice paper from X/@fred_stoddard , Kifle Belachew et al. discusses improved management of the legume Vicia faba crop to let it reach its potential pure.sruc.ac.uk/en/publicati...

Causal interpretations of family GWAS in the presence of heterogeneous effects bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Family-based GWAS have become the gold standard for assessing causal genetic effects. They’re often said to offer an unbiased estimate of the average causal effect (ATE) of an allele or PGS. Here, we (Carl Veller & @mollyprz.bsky.social ) evaluate such statements.
www.biorxiv.org/content/10.1... 1/n

So excited to announce our search for an Assistant Professor focused on understanding plant response to climate change! Come join us at UC Riverside aprecruit.ucr.edu/JPF01827