Melike Eren

I believe that, based on peace and a life worthy of human dignity, we can find common ground and be friends with all the working and loving peoples of the world.💜

Both countries are quite funny and friendly. Just now, someone offered us the letter 'ñ', and we offered them 'ğ' in return because in our culture, you never return a gift empty; if you give us a gift, you always give something back. It's a different atmosphere. We offered letters, lol.🫶🏻

On Twitter, efforts are being made to develop and advance Turkish-Spanish friendship. It all started with us stating that we don't want genocide and we don't want war in our region/world and that we don't want to support this violence.

graphical schematic of the meninges on top depicting the three layers [dura, arachnoid and pia] and other immune and vascular cell types. Inset shows Claudin-11 junction proteins connecting two sides of arachnoid barrier cells bottom schematic is the same but in inflammation with bacteria, junctions breakdown, depiction of cytokine release by vascular, meningeal and immune cells - at side of graphic is summary of defects we observe in infection: 'increased barrier permeability' 'mislocalization of Cldn11+ tight junction' 'BAM activation' and "increased inflammatory response'

🚨 New preprint from our lab led by Sophia Kim w/ @kellydoran.bsky.social group @cuanschutz.bsky.social -- using neonatal 🐭 model of bacterial meningitis ➡️ arachnoid barrier is leaky, Cldn11 junctions are disrupted & cytokines are part of the problem. Lots of 🤩🧠🦠🔬 & compelling data, check it out! 1/5

A genome-wide CRISPR screen reveals cancer-specific regul... Metastatic spread of cancer cells is driven by binding between...

"A genome-wide CRISPR screen reveals cancer-specific regulators of hyaluronan binding and cellular invasion"

www.researchhub.com/paper/110810...

@biorxivpreprint.bsky.social Macrophage-derived extracellular vesicles promote T cell-dependent inflammatory pain resolution
www.biorxiv.org/content/10.6...

Single-nucleus multiomic profiling of aging mouse substantia nigra reveals conserved gene alterations linked to #Parkinsons; Hsp90aa1 & Hsp90ab1⬆️in oligodendrocytes & microglia, Apoe⬆️in microglia, & protein folding genes⬆️in oligo.s at late aging stages
genome.cshlp.org/content/earl...

The TREM2 agonistic antibody AL002 in early Alzheimer’s disease: a phase 2 randomized trial - Nature Medicine In this phase 2, randomized trial in early Alzheimer’s disease, the TREM2 agonistic antibody AL002 showed target engagement but did not meet the primary endpoint of change from baseline in Clinical De...

Results from the #INVOKE2 phase 2 trial of the #TREM2 agonistic #antibody #AL002 in early #Alzheimers disease out now. Although #AL002 showed target engagement, no change in CDR-SB was seen. #microglia #dementia #AD
www.nature.com/articles/s41...

Two papers on important roles of the Arp2/3 complex in microglia in the CNS microenvironment by the labs of Jeremy Rotty and Tim Lämmermann @laemmermann-lab.bsky.social @mpi-ie.bsky.social and ZMBE @uni-muenster.de.

Read more:

link.springer.com/article/10.1...

link.springer.com/article/10.1...

Megan Doty et al discovered that myelin remains for weeks after cortical axons degenerate. We call the sheaths without an axon de-axoned myelin. During the slow, asynchronous, degeneration, microglia don't play a major role in clearing the axon or de-axoned myelin. www.science.org/doi/10.1126/...

New research maps how brain cells communicate across 13 neurodegenerative diseases AD, PD, ALS & more. Three key signaling axes between neurons, astrocytes & microglia explain why specific brain regions break down. A potential roadmap for precision therapies.
www.biorxiv.org/content/10.1...

Alzheimer’s may start with inflammation in the skin, lungs or gut The Alzheimer’s field is being turned on its head as mounting evidence points to the disease beginning outside the brain many years before symptoms start. This may mean we have to totally rethink how we approach preventing and treating the condition

The Alzheimer’s field is being turned on its head as mounting evidence points to the disease beginning outside the brain many years before symptoms start. This may mean we have to totally rethink how we approach preventing and treating the condition

someone needs to do something.Who are these "someones"? It is all of us. The responsibility for the children of this world regardless of their color, language, or religion the responsibility for the suffering of children in places whose existence you may not even be aware of, belongs to all of us.

are so intertwined, whether it's economic independence, occupation, or cultural occupation. I don't have children of my own, but every day I see child patients,I spend time with my niece&nephew who are very young, so much pain that can not fit into such tiny hands and hearts. Somewhere in the world

In Turkey, April 23rd is celebrated as National Sovereignty and Children's Day. In recent years, it deeply saddens me to see how connected these things are (the earthquakes in our country, the wars in our region, and globally, the criminal pedophilia networks)how protecting children and independence

The glycolytic metabolite phosphoenolpyruvate restricts cGAS-driven inflammation to promote healthy aging - Nature Aging The glycolytic metabolite phosphoenolpyruvate (PEP) is identified as a protective factor during aging. Acting as an endogenous inhibitor of cGAS−STING, PEP reduces inflammation and improves cognition ...

Phosphoenolpyruvate (PEP), a metabolite in glycolysis, directly inhibiting cyclic GMP–AMP synthase (cGAS). Biphasic fluctuation and eventual collapse of PEP levels during aging driving onset of inflammaging @nataging.nature.com
www.nature.com/articles/s43...
www.nature.com/articles/s43...

New review explores TREM2 in neurodegeneration; I think the #Parkinsons data is a little more mixed than indicated, but a useful overview nonetheless
www.nature.com/articles/s41...

very funny, she loves playing the violin, she gets mischievous and she loves tennis. fall off their bikes and get injured, even if they sprain their wrists or their hands bleed, my heart breaks. They are of similar ages in a neighboring country. Or they used to be.

I have a nephew around this age, his name is Timuçin, he wears glasses and uses a water bottle just like this one, he's only eight, he goes to primary school, he loves drawing picture, he plays basketball, and he has a sister named Umay. Umay is five years old, she goes to kindergarten very sweet,

A new film at the Venice Film Festival revisits the last moment of Hind Rajab

Hind Rajab was a five-year-old Palestinian girl in the Gaza Strip who was killed by the IDF

Her mom, Rana Faqih, talks about the incident, watch 👇

This replica of the car in which 6-year-old Palestinian child Hind Rajab was killed while fleeing Gaza City with her family last year was displayed in Bradford, UK, on what would have been her 7th birthday. The original vehicle was shot 335 times by Israeli forces.

Sanatçı milletvekili Yücel Arzen Hacıoğlulları:
Ses… Sadece Ses Kalıcıdır
Kurtulamıyorum bu seslerden
4 gündür uyuyamıyorum
Çaresini de bulamıyorum
O yüzden buraya getirdim
Gazi Meclis’te yankılansın istedim Başka nereye götürebilir ki?

#NeuroJobs

Women’s health Research into women’s health has suffered from historical neglect and lack of funding.

To mark International Women's Day on 8th March #IWD2026, the #NatureReviews Collection on women's health has been updated (go.nature.com/30kDWG3). The Collection covers various aspects of women's health and includes a new Primer on ovarian cancer from @natrevdiseaseprimers.nature.com

Physician Anna Broomall was born 179 years ago today. For three decades, she was a physician and professor in Philadelphia, working tirelessly to bring the antiseptic practices of Europe to the US to decrease the number of women dying from infections in childbirth.

#WomenInSTEM #MedSky #BookSky ⚕️

Egyptian nuclear physicist Sameera Moussa was born 109 years ago today. She was the first woman nuclear physicist in Egypt, and spent her career passionately pursuing the use of nuclear technology in medicine as a devoted member of the Atoms for Peace movement.

#WomenInSTEM #Physics #HistSci ⚛️🧪

The Strangers Within: Lynn Margulis and the Rebirth of Endosymbiosis In terms of cell count, ninety percent of you isn't you at all.  Bacteria, though by mass they only make up about two percent of a human being, account for nine out of every ten cells inside you.  Som...

Lynn Margulis would have been 88 years old today. Her 1966 paper "On the Origin of Mitoting Cells" was a powerful combination of older endosymbiotic theory with modern genetics that established the foundation for our modern understanding of eukaryotic cells.

tinyurl.com/2tj72jf8

#WomenInSTEM #WHM

OBS Immunology Seminar

Speakers:
🔹 Eva Conde García - @regeneron.com
🔹 Louise Webb - @babrahaminst.bsky.social - @linterman.bsky.social man.bsky.social

Moderator: @eugecc.bsky.social

📅 Thursday, March 12, 2026
⏰ 11am ET | 3pm GMT | 4pm CET
💻 us02web.zoom.us/meeting/regi...

Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection @natimmunol.nature.com @rockefeller.edu @biohub.org @danmucida.bsky.social @rohamparsa.bsky.social
www.nature.com/articles/s41...

Stand Up for Science plans second rally on March 7 Public health chaos and research funding cuts are inspiring nationwide pro-science protests against the Trump administration

Thank you @sciam.bsky.social and @meghanbartels.bsky.social for covering the @standupforscience.bsky.social National Day of Action on March 7th!

Save Science. Protect Health. Defend Democracy.

#standupforscience

www.scientificamerican.com/article/stan...