a temporary addition to the campus architecture..
05.03.2026 23:05
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a temporary addition to the campus architecture..
What music should we play to our cells? This was the start of an amazing journey from @ivaskalab.bsky.social at @turkubioscience.bsky.social with Jasmin Kaivola and collaborators @sarawickstrom.bsky.social and others to explore larynx cancer mechanosensitivity!
www.nature.com/articles/s41...
Snowy night @brownengineering.bsky.social
Today at Cell: A new #HallmarksofCancer review by Doug Hanahan: www.cell.com/cell/fulltex...
This review marks 25 years since the original seminal Cell review by Hanahan & Robert Weinberg and its impactful follow up in 2011.
@cp-cell.bsky.social @cellpress.bsky.social
not quite the correct geometry, but puppy collective migration seems to have analogies with epithelial spheroids ;)
www.youtube.com/watch?v=Zzg-...
and the Brown news release on our Nature Physics paper:
www.brown.edu/news/2026-01...
Published online today in Nature Physics - we show how multicellular spheroids round up and orbit, driving a deterministic transition to 3D matrix invasion at predictable locations.
Amazing work from @jiwon-kim.bsky.social, @htjeong.bsky.social and collaborators
www.nature.com/articles/s41...
Cell viscosity influences haematogenous dissemination and metastatic extravasation of tumour cells
go.nature.com/4jZ8OUu
In @jcb.org, Diaz & @mayorlab.bsky.social show that epithelial & mesenchymal cells navigate chemical cues via fundamentally different force-generating mechanisms, offering new insight into how diverse cell types achieve collective movement during development and disease. rupress.org/jcb/article/...
This octopus-camouflage inspired polymer can change colour and texture
Our paper describing the development of ShapeSpaceExplorer is now out: journals.plos.org/ploscompbiol... The software and documentation is available here: github.com/cmcb-warwick... Explainer thread below.
I'm very happy to share my first article as a corresponding author published in @natmethods.nature.com !! 😍
Some groups (like us) have developed complex 3DTFM methods in the last 15 years.
BUT its usage in studies that help better understand disease or development has been almost non-existent.
Belated post on lab alum Susan Leggett Ph.D. '18, featured by Matter as an emerging investigator in materials under 35. @brownengineering.bsky.social
www.cell.com/matter/fullt...
I like this movie, but a friend of mine likes to complain about the obvious stitching artifacts. I'll try harder next time, Michael. Vimentin (orange) and ER (blue) in an overnight acquisition.
New paper alert! We report that #zebrafish endodermal cells use contact inhibition of locomotion as a dispersal and spacing mechanism. It’s a neat example of large-scale patterns emerging from local interactions using a simple set of rules. Summary in the thread below 1/9
doi.org/10.1016/j.is...
Beautiful visualization of cancer cell metastatic colonization depicted by Brown's undergrad-led SciToons program @weldeiry.bsky.social #LegorretaCancerCenter
www.youtube.com/watch?v=W8P-...
Figure showing the interactive segmentation refinement in Toggle-Untoggle – de-selection, merging and manual annotation.
In their Tools and Resources article, Nina Grishchenko, Michael Olson and colleagues present Toogle-Untoogle, a cell segmentation tool with an interactive user verification interface.
journals.biologists.com/jcs/article/...
A shorthair domestic cat gazes upward.
The domestic cat may be a far more recent arrival to Europe than previously thought, a new Science study. finds. The results offer new insight into one of humanity’s most enigmatic animal companions and identify North Africa as the cradle of the modern housecat.
Learn more: https://scim.ag/44kov1S
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
I guess it never gets old...bc we love #CellMigration
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
Flashback #FluorescenceFriday to some of the first light-sheet imaging we were doing. Video shows the collecting duct system of the developing kidney labeled with a pan-cytokeratin antibody. Courtesy of former talented technician Deanna Hardesty.
What a crazy cool paper! First author @pierreucla.bsky.social with a large crew knocked it out of the park. (GIF below from @the.3i.social LLS) Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays www.pnas.org/doi/10.1073/...
Comment by Prof @icouzin.bsky.social that explores how collective intelligence emerges from local interactions in animal groups, and how these principles inform the design of swarm robotic systems. @natureportfolio.nature.com
@natcomms.nature.com #robotics
www.nature.com/articles/s41...
Honored to present last week at the Korea-US Collaborative Research Fund Investigator Meeting (kufhls.org)
Delighted to share our consortium's vision for bioengineering tumor models, alongside many stimulating talks by Korean and U.S. researchers on biotechnology
Postdoc Jiwon Kim from the @ianywonglab.bsky.social was named one of 30 female Rising Stars in MechE, and invited to a workshop to develop career skills, connect with a cohort of peers, and engage with mentors in anticipation of future careers in academia. engineering.brown.edu/news/2025-10...
deriving stuff on the blackboard does also helps with timing so that students can adsorb what's happening
Wong lab members are off to the Biomedical Engineering Society (BMES) 2025 Meeting in San Diego! Looking forward to presenting our latest work #BMES2025, @brownengineering.bsky.social @jiwon-kim.bsky.social @htjeong.bsky.social
